A5088673756- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- MRI in cancer diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Urologic and reproductive health conditions
- Advanced MRI Techniques and Applications
- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Cardiac Imaging and Diagnostics
- Molecular Biology Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- Radiation Dose and Imaging
- Urological Disorders and Treatments
- Bladder and Urothelial Cancer Treatments
- Urinary Bladder and Prostate Research
- Blood Pressure and Hypertension Studies
- Hormonal Regulation and Hypertension
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Heart Rate Variability and Autonomic Control
- Testicular diseases and treatments
- Colorectal Cancer Screening and Detection
- Pediatric Hepatobiliary Diseases and Treatments
- Adrenal and Paraganglionic Tumors
- Hepatocellular Carcinoma Treatment and Prognosis
Düsseldorf University Hospital
2013-2025
Heinrich Heine University Düsseldorf
2016-2025
Ruhr University Bochum
2023-2025
Universitätsklinik Marien Hospital Herne
2023-2025
Radiance Technologies (United States)
2022-2023
University College London
2023
Whipps Cross University Hospital
2023
Barts Health NHS Trust
2023
Royal Free London NHS Foundation Trust
2023
Royal London Hospital
2023
The Prostate Cancer Radiological Estimation of Change in Sequential Evaluation (PRECISE) recommendations standardise the reporting prostate magnetic resonance imaging (MRI) patients on active surveillance (AS) for cancer. An international consensus group recently updated these and identified areas uncertainty.
Magnetic resonance imaging guided biopsy is increasingly performed to diagnose prostate cancer. However, there a lack of well controlled, prospective trials support this treatment method. We prospectively compared magnetic in-bore with standard systematic transrectal ultrasound in naïve men increased specific antigen.We study 132 antigen (greater than 4 ng/ml). After 3 Tesla functional multiparametric patients were referred for lesions (maximum 3) followed by (12 cores). analyzed the...
Abstract This case of secondary sclerosing cholangitis (SSC‐CIP) emphasizes the need to provide follow‐up care for patients that have recovered from COVID‐19 in order understand complexity SARS‐CoV‐2 associated sequela.
There is no generally accepted screening strategy for prostate cancer (PCa). From February 2014 to December 2019 a randomized trial (PROBASE) recruited 46 642 men at age 45 determine the efficacy of risk-adapted prostate-specific antigen-based (PSA) screening, starting either or 50 years. PSA tests are used classify participants into low (<1.5 ng/mL), intermediate (1.5-2.99 ng/mL) high (≥3 risk group. In cases confirmed values ≥3 ng/mL recommended biopsy with multiparametric magnetic...
Background High variability in prostate MRI quality might reduce accuracy cancer detection. Purpose To prospectively evaluate the of scanners taking part control phase global PRIME (Prostate Imaging Using ± Contrast Enhancement) trial using Prostate Quality (PI-QUAL) standardized scoring system, give recommendations on how to improve protocols, and establish whether could be improved by these recommendations. Materials Methods In prospective clinical (PRIME), for each scanner, centers...
PURPOSE Image analysis is one of the most promising applications artificial intelligence (AI) in health care, potentially improving prediction, diagnosis, and treatment diseases. Although scientific advances this area critically depend on accessibility large-volume high-quality data, sharing data between institutions faces various ethical legal constraints as well organizational technical obstacles. METHODS The Joint Imaging Platform (JIP) German Cancer Consortium (DKTK) addresses these...
To compare the diagnostic performance of [18F]FDG PET/MRI, MRI, CT, and bone scintigraphy for detection metastases in initial staging primary breast cancer patients.A cohort 154 therapy-naive patients with newly diagnosed, histopathologically proven was enrolled this study prospectively. All underwent a whole-body computed tomography (CT) scan, prior to therapy. datasets were evaluated regarding presence metastases. McNemar χ2 test performed sensitivity specificity between...
Risk-adjusted screening for prostate cancer (PCa) aims to reduce harms by less frequent retesting, especially in men at a low risk of PCa. Definitions are based mainly on studies starting age 55-60 yr.
The objective of our study was to evaluate transrectal MRI-guided in-bore biopsy in patients who either were biopsy-naive (primary biopsy) or had undergone at least one previous negative ultrasound-guided (secondary with regard cancer detection rate, tumor localization, and lesion size.In total, 1602 cores from 297 consecutive (mean ± SD, 66.1 7.8 years; median prostate-specific antigen value, 8.2 ng/mL) primary (n = 160) secondary 137) prostate settings evaluated this retrospective study....
Abstract Evaluation of the current status, significance and availability multiparametric prostate MRI MRI-guided biopsy in Germany. A voluntary web-based questionnaire with 26 distinct items was emailed to members German Radiological Society (DRG) Professional Association Radiologists (BDR). The questions referred personal qualification, acquisition, quality, management MRI, assessment importance method. In total 182 questionnaires were captured from all 10 german postal regions (over 60%...
Abstract Aim of this study was to proof the concept optimizing contrast between prostate cancer (PC) and healthy tissue by DWI post-processing using a quadrature method. performed on 30 patients (median age 67 years, specific antigen 8.0 ng/ml) with PC clear MRI findings (PI-RADS 4 5). Multiparametric at 3 Tesla. A multi-shot readout segmentation (rs-EPI) plus zoomed single-shot imaging (z-EPI) sequence used in 15 (group 1) echo-planar (ss-EPI) rs-EPI 2). B-value images (b1000 b1800/2000)...
Cancer worry and risk perception are relevant psychological factors that influence preventive health behaviors. Therefore, a thorough understanding of the impact their occurrence manifestation is critical. The objective this study was to assess prevalence associated with about prostate cancer (PCa) absolute/comparative in community-based sample 45-year-old men. Data were collected within German PCa screening trial PROBASE. Variables assessed by self-report questionnaires clinical interview....
Die aktive Überwachung ("active surveillance", AS) verfolgt das Ziel, eine Übertherapie klinisch nicht signifikanter Prostatakarzinome (PCa) zu vermeiden. Sie wird für Patienten mit einem lokal begrenzten Niedrigrisiko-PCa stark empfohlen. Außerdem kann sie bei ausgewählten PCa der ISUP(International Society of Urological Pathology)-Gruppe 2 durchgeführt werden, sofern ein günstiges Risikoprofil vorliegt. Dieses ist histopathologisch durch einen geringen Anteil des Gleason-Musters 4 und...