A5041731471- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Urologic and reproductive health conditions
- Urinary Bladder and Prostate Research
- Urological Disorders and Treatments
- Bladder and Urothelial Cancer Treatments
- Pelvic floor disorders treatments
- Pediatric Urology and Nephrology Studies
- Kidney Stones and Urolithiasis Treatments
- Renal cell carcinoma treatment
- Anesthesia and Pain Management
- Urinary and Genital Oncology Studies
- Radiomics and Machine Learning in Medical Imaging
- Renal and related cancers
- Sexual function and dysfunction studies
- Ureteral procedures and complications
- Infectious Disease Case Reports and Treatments
- Muscle and Compartmental Disorders
- Advanced Radiotherapy Techniques
- Spine and Intervertebral Disc Pathology
- Abdominal Trauma and Injuries
- MRI in cancer diagnosis
- Nausea and vomiting management
- Diverticular Disease and Complications
- Autopsy Techniques and Outcomes
Mount Sinai Hospital
2025
Icahn School of Medicine at Mount Sinai
2018-2024
Mount Sinai Hospital
2019-2024
New York Proton Center
2019
King Edward Memorial Hospital and Seth G.S. Medical College
2015-2018
Kokilaben Dhirubhai Ambani Hospital
2018
King Edward Memorial Hospital Research Centre
2016
College of Medicine & JNM Hospital
2015
Background High variability in prostate MRI quality might reduce accuracy cancer detection. Purpose To prospectively evaluate the of scanners taking part control phase global PRIME (Prostate Imaging Using ± Contrast Enhancement) trial using Prostate Quality (PI-QUAL) standardized scoring system, give recommendations on how to improve protocols, and establish whether could be improved by these recommendations. Materials Methods In prospective clinical (PRIME), for each scanner, centers...
The hood technique is a modification of the robotic-assisted radical prostatectomy used for treatment prostate cancer. was developed in 2018 with goal preserving structures anterior to urethra during apical dissection facilitate early postoperative recovery urinary continence. Similar techniques have been published past, reporting excellent continence rates, including PERUSIA extraperitoneal and retrograde release neurovascular bundle. Additionally, puboprostatic ligament sparing shown...
The European Association of Urology guidelines recommend the use imaging, biomarkers, and risk calculators in men at prostate cancer. Risk predictive that combine multiparametric magnetic resonance imaging with prebiopsy variables aid as an individualized decision-making tool for patients cancer, advanced neural networking increases reliability these tools.
We compared the performance of multiparametric magnetic resonance imaging for prediction extraprostatic extension in African American and Caucasian men evaluated racial disparities pathological outcomes after radical prostatectomy.We identified 975 patients who underwent prostatectomy with preoperative between January 2013 April 2019 at our institution. Multivariable logistic regression analysis was performed predicting extension, high grade prostate cancer (final pathology GGG [Gleason...
Abstract Background The detection of prostate cancer requires histological confirmation in biopsy core. Currently, number unnecessary biopsies are being performed the United States. This is due to absence appropriate decision‐making protocol. Aim To develop and validate a 4K score/multiparametric magnetic resonance imaging (mpMRI)‐based nomogram predict (PCa), clinically significant (csPCa), unfavorable (uPCa). Methods Results Retrospective, single‐center study evaluating cohort 574 men with...
Multiparametric magnetic resonance imaging (MRI) is increasingly used to diagnose prostate cancer (PCa). It not yet established whether all men with negative MRI (Prostate Imaging-Reporting and Data System version 2 score <3) should undergo biopsy or not.To develop validate a prediction model that uses clinical parameters reduce unnecessary biopsies by predicting PCa clinically significant (csPCa) for findings who are at risk of harboring PCa.This was retrospective analysis 200 underwent...
Abstract PURPOSE To test the safety of sequential intratumoral plus systemic intramuscular injection poly-ICLC, and its efficacy in priming antitumor immune responses patients with prostate cancer (PCa). EXPERIMENTAL PROCEDURES This is an open-label dose-escalating phase 1 neoadjuvant clinical trial poly-ICLC (NCT03262103) 12 diagnosed clinically localized PCa plans to undergo radical prostatectomy (RP). Poly-ICLC was administered intratumorally (Artemis MRI-TRUS-guided) intramuscularly...
Background. Xanthogranulomatous inflammation is an uncommon affection of the female genital tract. The youngest case reported xanthogranulomatous salpingooophoritis in literature was by Shilpa et al. 2013 eighteen-year-old female. Case Report. We report a 2-year-old child with right-sided presented as mass abdomen. This documented literature. As per abdominal examination, there generalized distention abdomen and palpable which arising out pelvis more on right side. ultrasonography (USG)...
Prediction of extracapsular extension (ECE) is essential to achieve a balance between oncologic resection and neural tissue preservation. Microultrasound (MUS) an attractive alternative multiparametric magnetic resonance imaging (mpMRI) in the staging scenario.To create side-specific nomogram integrating clinicopathologic parameters MUS findings predict ipsilateral ECE guide nerve sparing.Prospective data were collected from consecutive patients who underwent robotic-assisted radical...
The study aims to identify the optimal 4Kscore thresholds determine need for a prostate biopsy when multiparametric magnetic resonance imaging (MRI) (mpMRI) is negative or indeterminate.
The natural progression of prostate cancer is primarily driven by an index lesion (IL). Studies have shown that different metastases within the same patient arise from a single precursor cell. Therefore, our aim to assess effectiveness transrectal microultrasound (MUS) in comparison multiparametric magnetic resonance imaging (mpMRI) for detecting IL cancer. We used quarter-mount pathological results as reference standard this evaluation.Three hundred and sixty-three patients who underwent...
Urolithiasis is less common in children than adults [1].The incidence generally about 2-3% [2].However its incidence, composition, location and clinical characteristics vary greatly from one country to another [3].This wide geographic variation related climatic, dietary socioeconomic factors.Genetic inheritance, nutrition, metabolic abnormalities, environmental factors, anatomical characteristics, calculusinducing medication are the factors predisposing for urolithiasis evaluation helps us...
The impact of pelvic inflammation on prostate cancer (PCa) biology and aggressive phenotype has never been studied. Our study objective was to evaluate the role PCa aggressiveness its association with clinical outcomes in patients following radical prostatectomy (RP). This conducted a retrospective single-institutional consecutive cohort 2278 who underwent robot-assisted laparoscopic (RALP) between 01/2013 10/2019. Data from 2085 were analyzed adverse pathology (AP), defined as Gleason Grade...
Background: Multiphoton microscopy (MPM) is a nonlinear optical imaging technology, allowing process-free of fresh tissue up to depth 0.5 mm, with combined signal autofluorescence and second harmonic generation. The absence bladder muscle in transurethral resection tumor (TURBT) increases risk residual disease, recurrence, understaging, an intraoperative assessment margins may avoid unnecessary TURBTs. Objective: objective this study was test the feasibility MPM real-time detection cold cup...
Bladder rupture following caesarian section is well documented complications. Intraperitoneal bladder normal vaginal delivery very rare. Hereby, we present a case report of intraperitoneal presented late delivery. We spontaneous urinary uneventful outlet forceps in 22-year-old primi gravid woman with gestational diabetes mellitus and fetal macrosomia who large ascites, anuria renal failure. Emergent exploratory laparotomy repair the helped to prevent its potential Postpartum patients undergo...
Objectives To evaluate if the blood biomarker, 4Kscore, in addition to multiparametric magnetic resonance imaging information could identify patients who would benefit from undergoing only a targeted biopsy. Methods We retrospectively analyzed population of 256 men with positive underwent standard + biopsy at Mount Sinai Hospital, New York, NY, USA. 4Kscore (OPKO Health, Miami, FL, USA) was sampled all before Uni‐ and multivariable binary logistic regression analyses were carried out predict...
<b>Introduction:</b> Holmium laser enucleation of the prostate (HoLEP) is a recognized option for surgical management benign prostatic hyperplasia. While parameters and techniques have been widely studied, morcellation still remain under-evaluated. The current study evaluates two commonly used devices their <i>in vivo</i> efficiency patient safety.<br><b>Materials Methods:</b> A total 222 patients who underwent HoLEP at medical centres between January 2011 to December 2013 by single surgeon...
Percutaneous nephrolithotomy (PCNL) is done under general anaesthesia in most of the centres. Associated complications and cost are higher for than regional anaesthesia. Present study designed to compare efficacy epidural block versus spinal with regards intraoperative mean arterial pressure, heart rate, postoperative pain intensity, analgesic requirement, Postoperative patient satisfaction patients undergoing PCNL.After taking Ethical Committee clearance, were randomly allocated into 2...
70%-80% of prostate cancer (PCa) biopsies performed in the US annually may be unnecessary. Specific antigen testing (PSA) and tans rectal ultrasound (TRUS) are imprecise predictive methods for risk PCa. Novel strategies critical to guide biopsy decision-making.We assessed utility accuracy combining Select MDx multiparametric magnetic resonance imaging (mpMRI) scores predicting PCa.Our study was conducted at Mount Sinai hospital Urology department New York City from January 2020 April 2021....