A5046931565- Advanced MRI Techniques and Applications
- Prostate Cancer Diagnosis and Treatment
- MRI in cancer diagnosis
- Advanced Neuroimaging Techniques and Applications
- Prostate Cancer Treatment and Research
- Radiomics and Machine Learning in Medical Imaging
- Acute Ischemic Stroke Management
- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- EEG and Brain-Computer Interfaces
- Cerebrovascular and Carotid Artery Diseases
- Urologic and reproductive health conditions
- Transcranial Magnetic Stimulation Studies
- Medical Imaging Techniques and Applications
- Visual perception and processing mechanisms
- Glioma Diagnosis and Treatment
- Lanthanide and Transition Metal Complexes
- Sports injuries and prevention
- Memory and Neural Mechanisms
- Dementia and Cognitive Impairment Research
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Advanced NMR Techniques and Applications
- Neural and Behavioral Psychology Studies
- Neuroscience and Music Perception
- Vestibular and auditory disorders
Turku University Hospital
2014-2024
University of Turku
2014-2024
IRCCS Ospedale San Raffaele
2021
Newcastle University
2010
Helsinki University Hospital
1997-2008
University of Helsinki
1991-2008
Finnish Defence Forces
2006-2008
Kuopio University Hospital
1999-2006
Massachusetts General Hospital
1991-2006
Massachusetts Institute of Technology
2006
PURPOSE: To assess the utility of magnetic resonance (MR) cerebral blood volume (CBV) maps in evaluation gliomas. MATERIALS AND METHODS: CBV from 19 patients with histologically proved gliomas were calculated dynamic MR image sets acquired echo-planar spin-echo imaging after intravenous injection gadolinium-based contrast material. RESULTS: The maximum varied 0.82 to 5.40 high-grade group (n = 13) and 1.01 1.21 low-grade 6). difference was statistically significant. Maximum associated...
MOTOR and visual cortices of normal volunteers were activated by transcranial magnetic stimulation. The electrical brain activity resulting from the brief electromagnetic pulse was recorded with high-resolution electroencephalography (HR-EEG) located using inversion algorithms. stimulation left sensorimotor hand area elicited an immediate response at stimulated site. activation had spread to adjacent ipsilateral motor areas within 5–10 ms homologous regions in opposite hemisphere 20 ms....
Purpose. Detection of bone metastases in breast and prostate cancer patients remains a major clinical challenge. The aim the current trial was to compare diagnostic accuracy 99mTc-hydroxymethane diphosphonate (99mTc-HDP) planar scintigraphy (BS), 99mTc-HDP SPECT, SPECT/CT, 18F-NaF PET/CT whole body 1.5 Tesla magnetic resonance imaging (MRI), including diffusion weighted imaging, (wbMRI+DWI) for detection high risk patients.Material methods. Twenty-six 27 at underwent BS, wbMRI+DWI. Five...
Abstract Magnetic resonance (MR) can offer a unique window on the structure/function relationships in brain, by utilizing established link between tissue function, metabolism, and hemodynamics. This report focuses recent applications of MR‐based crebral blood volume (CBV) imaging humans. Our methodology uses high‐speed “single‐shot” or echo planar techniques, which provide necessary temporal resolution for maping rapid cerebral transit contrast agents. These MR CBV mapping techniques have...
A sudden change in the direction of motion is a particularly salient and relevant feature visual information. Extensive research has identified cortical areas responsive to characterized their sensitivity different features motion, such as directional specificity. However, relatively little known about responses changes direction. Electrophysiological data from animals functional imaging humans suggest number brain presumably working network. Temporal patterns activity allow same network...
PURPOSE: To assess the value of magnetic resonance (MR) imaging in diagnosis pelvic inflammatory disease (PID) and to compare MR with transvaginal ultrasonography (US) laparoscopy. MATERIALS AND METHODS: Thirty consecutive patients hospitalized because they were clinically suspected having PID underwent US T1-weighted spin-echo, T2-weighted turbo inversion-recovery at 1.5 T. All laparoscopy after imaging. RESULTS: was laparoscopically proved 21 (70%) patients. The agreed that obtained 20...
Verbal fluency tests (VFTs) are suggested to assess frontal lobe function. This view is supported by functional imaging studies that report left activation during VFTs. VFTs require retrieval of semantically associated words from long-term memory storage. The neural networks participate in this process, however, largely unknown. These interest, given patients with early Alzheimer's disease, typically without pathology, often impaired In the present study, magnetic resonance was performed...
Depression affects up to 40% of patients with ischemic stroke. The relationship between site and size brain infarcts poststroke depression is still not well characterized. Further possible contribution interaction white matter lesions atrophy has been studied previously. We conducted a magnetic resonance image-based study the radiologic correlates in large, well-defined series stroke.Modified DSM-III-R DSM-IV criteria were used diagnose depressive disorders during comprehensive psychiatric...
Medial temporal lobe atrophy (MTA) is a sensitive radiologic marker for Alzheimer disease (AD) and associated with cognitive impairment. The value of MTA in the oldest old (>85 years old) largely unknown.A total 132 formalin-fixed brains from Vantaa 85+ community-based study were subjected to postmortem MRI. Visual ratings determined blinded fashion compared neuropathologic findings clinical assessment (dementia according Diagnostic Statistical Manual Mental Disorders-III-R).A strong...
To evaluate in a multi-institutional study whether radiomic features useful for prostate cancer (PCa) detection from 3 Tesla (T) multi-parametric MRI (mpMRI) the transition zone (TZ) differ those peripheral (PZ).3T mpMRI, including T2-weighted (T2w), apparent diffusion coefficient (ADC) maps, and dynamic contrast-enhanced (DCE-MRI), were retrospectively obtained 80 patients at three institutions. This was approved by institutional review board of each participating institution. First-order...
Purpose To develop and validate a classifier system for prediction of prostate cancer (PCa) Gleason score (GS) using radiomics texture features T2-weighted imaging (T2w), diffusion weighted (DWI) acquired high b values, T2-mapping (T2). Methods T2w, DWI (12 0–2000 s/mm2), T2 data sets 62 patients with histologically confirmed PCa were at 3T surface array coils. The post-processed monoexponential kurtosis models, while T2w was standardized to common scale. Local statistics 8 different...
Computed tomography (CT) and bone scintigraphy (BS) are the imaging modalities currently used for distant metastasis staging of prostate cancer (PCa).To compare standard with newer potentially more accurate modalities.This prospective, single-centre trial (NCT03537391) enrolled 80 patients newly diagnosed high-risk PCa (International Society Urological Pathology grade group ≥3 and/or prostate-specific antigen [PSA] ≥20 cT ≥ T3; March 2018-June 2019) to undergo primary two three advanced...
Background and Purpose —More effective imaging methods are needed to overcome the limitations of CT in investigation treatments for acute ischemic stroke. Diffusion-weighted MRI (DWI) is sensitive detecting infarcted brain tissue, whereas perfusion-weighted (PWI) can detect perfusion same session. Combining these may help identifying penumbra, which an important concept hemodynamics The purpose this study was determine whether combined DWI PWI (<24 hours) stroke predict infarct growth...