A5083953327- Dementia and Cognitive Impairment Research
- Heart Failure Treatment and Management
- Blood Pressure and Hypertension Studies
- Frailty in Older Adults
- Parkinson's Disease Mechanisms and Treatments
- Nutrition and Health in Aging
- Health Systems, Economic Evaluations, Quality of Life
- Geriatric Care and Nursing Homes
- Pharmaceutical Practices and Patient Outcomes
- Chronic Disease Management Strategies
- Intensive Care Unit Cognitive Disorders
- Diet and metabolism studies
- Cardiovascular Function and Risk Factors
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal disorders and treatments
- Hip and Femur Fractures
- Dialysis and Renal Disease Management
- Phenothiazines and Benzothiazines Synthesis and Activities
- Pharmacovigilance and Adverse Drug Reactions
- Cardiac, Anesthesia and Surgical Outcomes
- Nutritional Studies and Diet
- Diabetes Treatment and Management
- Dysphagia Assessment and Management
- COVID-19 Clinical Research Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
Università Cattolica del Sacro Cuore
2015-2024
Agostino Gemelli University Polyclinic
2017-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2024
ORCID
2024
Azienda di Rilievo Nazionale ed Alta Specializzazione
2020
Catholic University of America
2000-2014
Ospedale San Carlo
2013
University of the Sacred Heart
2001-2013
Sapienza University of Rome
2000-2013
University of Messina
2003-2006
<h3>Abstract</h3> <b>Objective:</b> To evaluate the impact of a programme integrated social and medical care among frail elderly people living in community. <b>Design:</b> Randomised study with 1 year follow up. <b>Setting:</b> Town northern Italy (Rovereto). <b>Subjects:</b> 200 older already receiving conventional community services. <b>Intervention:</b> Random allocation to an intervention group case management or control care. <b>Main outcome measures:</b> Admission institution, use...
Cognitive impairment has been reported in middle aged patients with end stage heart failure. This cross sectional study assessed the prevalence and determinants of cognitive dysfunction older mild to moderate failure.57 consecutive (mean age 76.7 years) chronic failure underwent physical examination, blood chemistry, urinalysis, chest radiography ECG, Doppler echocardiography, mini mental state examination (MMSE), deterioration battery, depression scale Center for Epidemiological Studies...
Arterial hypotension has been associated with increased risk of dementia in some large prospective studies; and cognitive impairment is common among elderly left ventricular function. The authors assessed whether arterial might be older subjects heart failure.This study involved all 13,635 patients (of whom 1,583 had failure) without cerebrovascular disease or AD, admitted to 81 Italian academic hospitals 1995 1997. association between blood pressure (as indicated by a Hodkinson Mental Test...
OBJECTIVES: To determine if body mass index (BMI = weight/height2), predictive of mortality in seriously ill hospitalized and institutionalized patients, is also a longitudinal epidemiologic study. DESIGN: A prospective cohort SETTING: Rovereto, town northern Italy. PARTICIPANTS: consecutive sample 214 patients aged 81.2 ± 7.3 years receiving community care services. MAIN OUTCOME MEASURES: Malnutrition mortality. RESULTS: According to logistic regression analysis, malnutrition status,...
A fall is an event where a person unintentionally and traumatically finds themselves on the floor or lower level. Falls are very common, especially in older adult population. One four people falls at least once year after age 65. Because of falls, there can be injuries, whereby impairment health status. Fractures, reduced mobility, disability, need for institutionalization potential consequences falls. In patients, frail ones, these types complications more common. There several risk factors...
Background and Study Aims: There have been growing concerns about the long-term sequelae of endoscopic sphincterotomy (ES). The aims study were to evaluate clinical outcome ES for choledocholithiasis identify predictors recurrence. Patients Methods: A total 529 patients (233 men, 296 women; mean age 63, range 9 - 88) who underwent successful evaluated. Follow-up data obtained retrospectively. Statistical analyses carried out 334 had a follow-up at least 5 years or Results: Immediate...
Aims Cognitive dysfunction is a prevalent condition among patients with heart failure, and independently associated disability mortality. Angiotensin-converting enzyme (ACE)-inhibitors might increase cerebral blood flow in subjects failure. Our aim was to assess whether starting treatment ACE-inhibitors improve cognition
It has been well assessed that women have widely under-represented in cardiovascular clinical trials. Moreover, a significant discrepancy pharmacological and interventional strategies reported. Therefore, poor outcomes more mortality shown many diseases. Pharmacokinetic pharmacodynamic differences drug metabolism also described so effectiveness could be different according to sex. However, awareness about the gender gap remains too scarce. Consequently, gender-specific guidelines are...
To evaluate the effect of medical indicators health status on functional gain during rehabilitation frail older patients.Observational study.A hospital geriatric department (Catholic University Rome).Two hundred forty-four patients admitted consecutively for after acute illnesses between March 1999 and June 2000.Patients were evaluated with Minimum Data Set Post-Acute Care (MDS-PAC) assessment form soon admission every 2 weeks thereafter. Two summary scales based MDS-PAC items are designed...
Background: Moderate alcohol consumption has been associated in several studies with decreased risk of cardiovascular and cerebrovascular events; however, available data on the effects intake cognitive functioning are conflicting. We assessed association between impairment a series older subjects enrolled multicenter pharmacoepidemiology survey. Methods: The average alcoholic performance was 15,807 patients admitted to participating centers during survey periods. Demographic variables,...
This exploratory, randomised, double-blind, double-dummy, multicentre, cross-over study explored the effect of 6 weeks treatment with tiotropium/olodaterol (T/O) versus fluticasone propionate/salmeterol (F/S) on left ventricular filling in patients chronic obstructive pulmonary disease functional residual capacity (FRC) >120% predicted and postbronchodilator improvement FRC ≥7.5%. Overall, 76 were randomised across nine sites. Treatment T/O or F/S increased end-diastolic volume index from...
Abstract Background Population‐based surveys on the quality of life people with Down syndrome (DS) are difficult to perform because ethical and legal policies regarding privacy confidential information, but they essential for service planning. Little is known about sample size variability DS living in city Rome, which has a population 2.7 million inhabitants. The aim present study explore needs challenges health, social integration daily life, Rome. Methodology A cross‐sectional,...
ABSTRACT Treatment with proton-pump inhibitors (PPIs) might be associated neuropsychological side effects. We examined the association between use of PPIs and depressive symptoms in an elderly population. Mood was assessed by 30-item Geriatric Depression Scale (GDS) all 344 inhabitants Tuscania (Italy) aged 75 years over, without exclusion criteria; depression defined a GDS score ≥11. Use higher linear regression analysis (B = 2.43; 95% CI 0.49–4.38; p 0.014) after adjusting; also, increased...
Objectives The cutoff scores for the Geriatric Depression Scale (GDS) commonly adopted in clinical and research settings are based upon other neuropsychological tests. However, any intervention depression should aim at improving subjective quality of life (QoL). We searched a GDS level that might identify decrease perceived QoL using scale also allows formal cost‐effectiveness calculations. Methods Quality was assessed by Health Utilities Index, Mark 3 all 344 residents Tuscania (Italy) aged...
It is well established that gender strongly influences cardiovascular risk factors, playing a crucial role in prevention, clinical pathways, diagnostic approach and treatment. Beyond the sex, which biological factor, entails socio-cultural condition impacts access quality of care due to structural institutional barriers. However, despite its great importance, this issue has not been adequately covered. Indeed sex differences scarcely impact approach, creating lot disparities outcomes...
OBJECTIVES: To evaluate the impact of a new assessment system, Minimum Data Set for Home Care (MDS‐HC), on functional status and hospitalization rates frail, community‐dwelling older people. DESIGN: Single‐blind randomized trial with 1‐year follow‐up. SETTING: Bergamo, Italy. PARTICIPANTS: All 187 subjects who were eligible home care services delivered by two Health Districts between September 1998 April 1999. INTERVENTION: Random allocation to an intervention group undergoing MDS‐HC or...