- Microfluidic and Capillary Electrophoresis Applications
- Social Sciences and Governance
- Healthcare Systems and Practices
- Analytical Chemistry and Chromatography
- Maternal and Perinatal Health Interventions
- Maternal and fetal healthcare
- Innovative Microfluidic and Catalytic Techniques Innovation
- Business Strategy and Innovation
- Mass Spectrometry Techniques and Applications
- French Urban and Social Studies
- COVID-19 Impact on Reproduction
- Management and Organizational Studies
- Emergency and Acute Care Studies
- Maternal Mental Health During Pregnancy and Postpartum
- Assisted Reproductive Technology and Twin Pregnancy
- Vaccine Coverage and Hesitancy
- Innovation and Knowledge Management
- Accounting and Organizational Management
- Nitric Oxide and Endothelin Effects
- Heart Rate Variability and Autonomic Control
- Patient Satisfaction in Healthcare
- COVID-19 and healthcare impacts
- Preterm Birth and Chorioamnionitis
- Health, Medicine and Society
- Education, sociology, and vocational training
Centre Hospitalier Intercommunal de Poissy
2015-2025
Université Paris-Saclay
2019-2025
Centre de recherche en Epidémiologie et Santé des Populations
2021-2025
Université de Versailles Saint-Quentin-en-Yvelines
2017-2025
Inserm
2015-2025
Centre de Recherche Épidémiologie et Statistique
2024
Hôtel-Dieu de Paris
2024
Université Paris Sciences et Lettres
2024
Centre National de la Recherche Scientifique
1995-2024
Risques cliniques et sécurité en santé des femmes et en santé périnatale
2017-2024
Angiotensin I-converting enzyme (ACE) is a zinc-dipeptidyl carboxypeptidase, which contains two similar domains, each possessing functional active site. Respective involvement of site in the degradation circulating peptide N-acetyl-seryl-aspartyl-lysyl-proline (AcSDKP), negative regulator hematopoietic stem cell proliferation, was studied by using wild-type recombinant ACE and full-length mutants containing single Both N- C-active sites exhibit dipeptidyl activity toward AcSDKP, with Km...
To ensure the success of COVID-19 vaccination, public authorities need to have support entire population and build vaccine confidence. Identifying understanding determinants acceptance is essential for conducting strategy. The aim was estimate hesitancy among healthcare students in France investigate associated factors.A web-based cross-sectional study conducted a large French University greater Paris area, 4927 from different training courses such as medicine studies, midwifery...
The objectives of the present experiments were to assess effects endothelin‐1 on macrovascular permeability in selected vascular beds, study involvement platelet‐activating factor (PAF) responses and examine combined administration PAF conscious rats. Intravenous bolus injection (0.1–2 nmol kg −1 ) resulted a dose‐dependent biphasic change mean arterial blood pressure (MABP) with initial transient hypotension followed by prolonged pressor action. These changes accompanied increase...
Postpartum hemorrhage (PPH) remains a leading cause of maternal morbidity and mortality worldwide. It is therefore important to improve our understanding the risk factors for PPH according parity, in particular, those linked modifiable obstetric practices. The aim this study was assess by duration second third stages labor, stratified parity. This based on secondary analysis data from participants randomized controlled trial. A sample women three university hospitals France aged at least 18...
Separations using CE employing non-aqueous BGE are already as well established separations in aqueous buffers. The separation mechanisms achiral with BGEs most likely similar to those However, for the of enantiomers involving their interaction chiral buffer additives, might be very different and BGEs. While hypothesis regarding distinct enantiomer has been mentioned several papers, no direct proof this reported date. In present study, propranolol were resolved methanolic two single isomer...
In the present study migration order of propranolol enantiomers with various native CDs and neutral charged CD derivatives was examined in capillary electrophoresis (CE). The reversal enantiomer observed due to sulfation beta-CD on its primary hydroxy groups. structures intermolecular selector-select temporary diastereomeric associates solution were elucidated based 1D rotating frame nuclear Overhauser effect spectroscopy (1D ROESY) experiments. Major structural differences between complexes...
Objectives Our primary and secondary objectives were to measure understand the determinants of independent midwives' implementation teleconsultations their intention continue these in future. Design A two-phase mixed-methods approach: (1) quantitative data factors determining initiation continuation teleconsultation, collected by an online survey from 29 April 15 May 2020, at end first COVID-19 lockdown, followed (2) qualitative determinants, interviewing some participants May–July 2020...
The objective of the present experiments was to assess involvement endothelin‐A (ET A ) receptors in mediating effects endothelin‐1 on microvascular permeability conscious rats. Bolus injection (0.1 and 1 nmol kg −1 , i.v.) resulted a dose‐dependent prolonged pressor effect preceded by transient depressor response. These changes were accompanied loss plasma volume. Endothelin‐1 (1 enhanced vascular upper lower bronchi, kidney, stomach, duodenum spleen (up 270%) as measured extravasation...
1 The objectives of the present experiments were to assess role endogenous nitric oxide (NO) in mediating and/or modulating effects endothelin-1 (ET-1) on blood pressure and microvascular permeability conscious rats. 2 Intravenous administration NO synthesis inhibitors, NG-monomethyl-l-arginine (l-NMMA) or NG-nitro-l-arginine methyl ester (l-NAME) at a dose (25 mg kg−1 kg−1, respectively) which evoked maximum increase mean arterial (MABP) significantly attenuated (by about 40%) vasodepressor...
The influence of the BGE composition, including addition a single-isomer sulfated beta-CD derivative, on ionization performance model compound carvedilol in NACE-ESI-MS was studied using an alternative infusion method. This approach employs voltage-induced containing analyte, and takes into account effects variations EOF effective analyte mobility ESI-MS intensity. First, optimal composition sheath liquid for CE-MS terms signal abundance stability determined. ammonium formate, acetate,...
As a field of knowledge, strategy has been taught and practised for over half century. However, there is still distinct lack consensus surrounding the effectiveness in public administrations. This thematic issue International Review Administrative Sciences devoted to advanced research which claims that age results-based management, leaders must opt process-based approach strategy. In doing so, emphasis put on complexity strategic processes make it possible support maintain institutions serve...
Objective To evaluate whether responses to dynamic case-vignettes accurately reflect actual practices in complex emergency situations. We hypothesized that when obstetricians were faced with vignette of situation identical one they previously managed, would report the management strategy actually used. On other hand, there is no reason suppose their response a based on source case managed by another obstetrician be same as management. Methods A multicenter vignette-based study was used 7...