A5011569065- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Mechanical Circulatory Support Devices
- Lung Cancer Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Congenital Heart Disease Studies
- Infectious Aortic and Vascular Conditions
- Inflammatory Biomarkers in Disease Prognosis
- Cancer, Lipids, and Metabolism
- Myasthenia Gravis and Thymoma
- Trauma Management and Diagnosis
- Venous Thromboembolism Diagnosis and Management
- Medical Imaging and Pathology Studies
- Cardiac and Coronary Surgery Techniques
- Infective Endocarditis Diagnosis and Management
- Esophageal and GI Pathology
- Abdominal vascular conditions and treatments
- Cardiac Arrhythmias and Treatments
- Cardiovascular Function and Risk Factors
- Pleural and Pulmonary Diseases
- Cardiac tumors and thrombi
Miyazaki Prefectural Hospital
2010-2022
University of Miyazaki
2013-2022
University of Miyazaki Hospital
2015-2020
University of Alabama
2014
Saitama Cancer Center
2008
Miyazaki Welfare Medical College
1988-2004
Cleveland Clinic
2004
Kyoto Prefectural University of Medicine
1988-2003
Foundation for Ichthyosis and Related Skin Types
2003
Second Hospital of Nanchang
2001
Abdominal aortic aneurysm (AAA) is histologically characterized by medial degeneration and various degrees of chronic adventitial inflammation, although the mechanisms for progression are poorly understood. In present study, we carried out histological study AAA tissues patients, interventional animal cell culture experiments to investigate a role mast cells in pathogenesis AAA. The number was found increase outer media or adventitia human AAA, showing positive correlation between diameter....
The systemic immune-inflammation index (SII) is reported to be associated with clinical outcomes and has been proven a promising prognostic indicator in several solid tumor types. To the best of our knowledge, however, no studies regarding SII patients resectable non-small cell lung cancer (NSCLC) are available.Three hundred forty-one NSCLC who underwent surgery at Institution between 2008 2012 were included. was calculated using formula: platelet count × neutrophil/lymphocyte count. optimal...
The usefulness of a recently developed advanced lung cancer inflammation index (ALI) has been reported in non-small-cell (NSCLC) and small-cell cancer. However, no previous studies have examined the prognostic significance ALI patients with operable NSCLC. Therefore, aim this study was to explore relationship between prognosis resected NSCLC.Three hundred forty-three NSCLC who underwent surgery at our institution 2008 2012 were included. score calculated as body mass × serum...
Inflammation-based prognostic scores, including Glasgow score (GPS), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), nutritional index (PNI), systemic immune-inflammation (SII) and advance lung cancer inflammation (ALI) are reported to be associated with survival in patients non-small cell (NSCLC). However, at present, there no studies that compared these scoring systems for resectable NSCLC.Three hundred forty-one NSCLC who underwent surgery our institution were...
PROBLEM: Changes in the frequency of dendritic cell (DC) subsets peripheral blood were analyzed as pregnancy progressed, and effects human chorionic gonadotropin (hCG) on myeloid lymphoid DC phenotypically functionally examined. METHOD OF STUDY: Two major DCs prepared from by flowcytometry. Major histocompatibility complex class II molecules adhesion/costimulatory examined before after culture with hCG. hCG receptors both reverse transcriptase‐polymerase chain reaction (RT‐PCR). RESULTS: The...
Venous tumor thrombus of thyroid cancer that extend to the great vein is rare, and management criteria for venous have not been established yet. We report a surgical case carcinoma with extensive in superior vena cava (SVC) consider appropriate treatment strategy thrombus.A 75-year-old woman consulted our hospital because an thrombus. Computed tomography (CT) revealed solitary mass continuous left internal jugular vein, innominate SVC. planned complete resection. During operation, SVC...
Background: We retrospectively analysed the prognostic significance of a tumor marker index (TMI) based on preoperative serum carcinoembryonic antigen (CEA) and Krebs von den Lungen-6 (KL-6) levels in nonsmall cell lung cancer (NSCLC) patients. Materials Methods: enrolled 176 NSCLC patients who had CEA KL-6 level measurements undergone curative surgery between 2009 2011. Results: The 5-year disease-specific survival with high was significantly poorer compared that normal levels. value for...
Renal metastasis from non-small-cell lung cancer is rather uncommon; isolated especially rare. Herein we report 2 cases who developed a solitary renal after undergoing curative resection for cancer. They received nephrectomy.
In non-small cell lung cancer (NSCLC) patients with preoperative high serum carcinoembryonic antigen (CEA) level, a persistently CEA level after surgery have been reported to poor prognosis. addition, in other cancers, the post/preoperative ratio has as useful parameter.We enrolled 123 NSCLC levels (≥ 5 ng/mL) who underwent curative between 2004 and 2011. Prognostic significance of postoperative was examined.The 5-year survival poor. On hand, normal had significant favorable The ratio>1...
Objective—The purpose of the present study was to evaluate effects pulsatile cardiopulmonary bypass (CPB) on sheep regional renal blood flow by comparing and non‐pulsatile perfusion at two different rates. Design—Seven female Suffolk were used animals perfused with CPB rates 60 100 ml/min/kg. Regional measured colored microsphere method. General linear model ANOVA performed analyze data. Results—Regional significantly higher in both outer middle cortices compared (outer cortex: CPB, 381 ±...
Previous study of ours showed that advanced lung cancer inflammation index (ALI) and C-reactive protein (CRP) are independent significant prognostic factors in operable non-small cell (NSCLC) patients. Since both ALI CRP markers inflammation, the aim this was to examine whether combination is a indicator resected NSCLC or not.Three hundred forty-one patients who underwent surgery at our institution between 2008 2012 were included. score calculated as BMI × ALB/NLR with indicating body mass...
Inflammation and hypertension contribute to the progression of atherosclerotic aneurysm in aorta. Vascular cell metabolism is regarded modulate atherogenesis, but metabolic alterations that occur remain unknown. The present study aimed identify pathways metabolites aneurysmal walls examine their roles atherogenesis.Gene expression using microarray metabolite levels early lesions obtained from 42 patients undergoing aortic surgery were investigated (early lesion n=11, n=35) capillary...
The index of motor current amplitude (ICA) has feasibility in continuous-flow ventricular assist device control. It can demonstrate the safe range pump speed, which exists between starting point total assistance (t-point) and sucking (s-point). objective this study was to investigate how ICA characteristic curve changes with each condition contractility, preload, afterload changes. We changed afterload, contractility closed-mock circulation plotted change value against speed. Then shift...
An enzyme linked immunosorbent assay (ELISA) was used to estimate the production of intracellular and extracellular interleukin-1 (IL-1) alpha beta by peripheral blood monocytes from 26 patients with various connective tissue diseases (CTD), including 19 systemic lupus erythematosus, four progressive sclerosis, two mixed disease, one Sjögren9s syndrome. Monocytes obtained CTD serum antibodies nuclear ribonucleoprotein (nRNP) released significantly higher concentrations IL-1 beta, whereas...
A left ventricular assist device (LVAD) is an effective method to rescue severe heart failure. Although some require a biventricular assist, the control for (BVAD) with rotary pump rarely shown. The objective of this study was investigate strategy controlling BVAD pumps by in vivo studies. Using 5 piglets, we set through thoracotomy and made global ischemia 30 min clamping base ascending aorta. After unclamping, analysis pumping performance acted 6 h reperfusion. We target flow LVAD right...