Background. Genetic polymorphisms of angiotensin-converting enzyme (ACE) and apolipoprotein E (APOE) have been reported to be associated with human longevity dementia in the elderly. However, whether such putative genes exert same effects on different ethnic groups living environments is not well known.

To evaluate the effect of nitroglycerin on diagnostic accuracy electrocardiogram-gated coronary computed tomography (CT) angiography in patients with suspected artery disease.Computed was performed 76 using a 16-slice CT scanner. Forty-six received sublingual 1 minute before scanning (the NTG group), but other 30 did not non-NTG group). No statistically significant differences were evident between these 2 groups terms clinical and demographic characteristics. Significant stenosis (> or =50%...

711 Background: In metastatic pancreatic cancer (MPC), hepatic metastasis is uniformly counted as just ‘one organ metastasis’ regardless of its tumor burden. This study aims to develop a novel stratification system for liver based on burden, and evaluate prognostic significance in MPC patients. Methods: Patients with treated at Seoul National University Bundang Hospital from 2011 2021 were included the training cohort. liver-only selected analysis. Liver burden was categorized by number...

5-Aryl-2,2-dialkyl-4-phenyl-3(2H)furanone derivatives were studied as a novel class of selective cyclooxygenase-2 inhibitors with regard to synthesis, in vitro SAR, antiinflammatory activities, pharmacokinetic considerations, and gastric safety. 1f, representative compound for methyl sulfone derivatives, showed COX-2 IC50 comparable that rofecoxib. In case 20b, sulfonamide potent ED50 0.1 mg kg-1 day-1 was observed against adjuvant-induced arthritis by preventive model, positioning 20b one...

MR imaging of Ebstein's anomaly the tricuspid valve.Y H Choi, J Park, Y Choe and S YooAudio Available | Share

Background Two types of self-expandable metal stents (SEMS) are available for malignant distal biliary obstruction: fully covered SEMS (FCSEMS) and uncovered SEMS. FCSEMS can prevent stent ingrowth, but a major concern is spontaneous migration. This study aimed to determine whether the additional insertion double-pigtail plastic anchor Methods 68 patients with unresectable, malignant, distal, obstruction were included in this multicenter, randomized, superiority trial. The randomly assigned...

Treatment of residual intraductal lesions after endoscopic papillectomy for ampullary adenomas is relatively difficult. Few studies have been conducted using radiofrequency ablation (RFA) in the treatment such lesions, and no study has aimed to reduce side effects excessive heat caused by RFA. Recently, a temperature-controlled RFA probe was developed avoid heat. This investigate safety this new adenoma.Patients who received between November 2017 June 2019 were retrospectively reviewed. A...

Differential diagnosis of true gallbladder polyps remains a challenging task. This study aimed to differentiate in ultrasound images using deep learning, especially less than 20 mm size, where clinical distinction is necessary. A total 501 patients with polyp pathology confirmed through cholecystectomy were enrolled from two tertiary hospitals. Abdominal these analyzed an ensemble model combining three convolutional neural network (CNN) models and 5-fold cross-validation. True the that...

Although diabetes is reportedly associated with the occurrence of acute pancreatitis (AP), risk AP according to duration and severity not yet clear. We aimed investigate based on glycemic status presence comorbidities using a nationwide population-based study.We enrolled 3,912,496 adults who underwent health examinations under National Health Insurance Service in 2009. All participants were categorized by as normoglycemic, impaired fasting glucose (IFG), or diabetes. Baseline characteristics...

Purpose: Laparoscopic choledochal cyst excision with Roux-en-Y hepati cojejunostomy (LCE) in children is being attempted more frequently around the world, and although it has been performed Korea, no publication published on it.However, cholangitis and/or pancreatitis are limitations that make open conversion likely.The aims of this study, through a retrospective clinical analysis, were to prove efficacy LCE validate preoperative management expands its indications. Methods:From May 2011...

Right lobe (RL) living donor liver transplantation (LDLT) usually includes 2 bile duct anastomosis sites, namely, the right anterior and posterior segmental ducts. This study aimed to evaluate optimal treatment for biliary strictures following RL LDLT with respect unilateral or bilateral drainage techniques. From January 2005 December 2017, 883 patients at Seoul National University Hospital underwent LDLT. Of these, 110 were enrolled who had duct‐to‐duct sites considered risk of developing...

Background The impact of obesity on survival is known to vary in different cancers. Advanced biliary tract cancer was rarely analyzed about the relationship between and prognosis. We performed this study evaluate BMI body weight change as prognostic factors for advanced patients with palliative chemotherapy. Methods Between January 2005 December 2016, two hundred seventy-six who underwent chemotherapy were retrospectively analyzed. (kg/m2) clinical outcomes including overall progression-free...

Circulating tumor cells (CTCs) are a promising prognostic biomarker for cancers. However, the paucity of CTCs in peripheral blood early-stage cancer is major challenge. Our study aimed to investigate whether portal venous can be early recurrence and poor prognosis pancreatic cancer. Patients who underwent upfront curative surgery resectable were consecutively enrolled this prospective study. Intraoperatively, 7.5 mL was collected, CTC detection identification performed using...

Abstract Background The size of gallbladder (GB) polyps is a representative risk factor for neoplastic polyps. However, whether growth rate during follow‐up associated with remains unclear. Methods From 2009 to 2019, cohort patients GB who underwent cholecystectomy was enrolled. We included only at least two abdominal ultrasonography procedures 6 months apart prior cholecystectomy. Performance and optimal cutoff value polyp predicting were estimated using receiver operating characteristic...

The hypertriglyceridaemic waist (HTGW) phenotype, an indicator to assess metabolic syndrome, could be a useful predictive marker for the risk of acute pancreatitis. This study aimed evaluate association between HTGW phenotype and pancreatitis with nationwide population-based cohort.A retrospective, cohort study.Registry health check-up result from Korean National Health Insurance Service.A total 3 912 551 adults who underwent checkups under Service in 2009 were enrolled this study.Subjects...

Eui Joo Kim, Sang Hyub Lee, Min Kyu Jung, Dong Kee Jang, Jung Hyun Jo, Jae Wan Choe, Sung Yong Han, Young Hoon Choi, Seong-Hun Jin Myung Park, Kyu-Hyun Paik. Gut and Liver -0001;0:. https://doi.org/10.5009/gnl230350

In this paper, we propose novel location based service (LBS) technique using visible light communications (VLC) for indoor service. As an LBS technique, the VLC is employed due to its many advantages awareness and performance presented through simulations. The of evaluated in terms bit error rate error. results paper can be applicable with high accuracy.

We report a case of primary penile undifferentiated sarcoma. A 16-year-old adolescent man visited Pusan National University Hospital complaining painless mass on his penis that was increasing in size. Magnetic resonance images revealed 5×5-cm and pathological examinations small round cell sarcomas with neuroendocrine differentiation. The tumor, which had metastatic pulmonary nodules, treated by tumorectomy systemic chemotherapy. Thirty-four months after the initial diagnosis, patient still...

Amorphous CoSiB/Pt multilayer is a perpendicular magnetic anisotropy material to achieve high squareness, low coercivity, strong anisotropy, and smooth domain wall (DW) motion, because of the smoother interface compared with crystalline multilayers. For [CoSiB(6 Å)/Pt (14 Å)]N multilayers N = 3, 6, 9, we studied field-induced DW dynamics. The effective constant K1eff 1.5 × 106 erg/cm3 for all values, linear increment coercive field Hc gives exchange coupling J. By analyzing dependence images...