Linxiang Zhang

ORCID: 0000-0002-2645-9472
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Research Areas
  • Marine and coastal ecosystems
  • Bone Tissue Engineering Materials
  • Quantum Dots Synthesis And Properties
  • Cancer Immunotherapy and Biomarkers
  • Photoacoustic and Ultrasonic Imaging
  • Electrospun Nanofibers in Biomedical Applications
  • Ferroptosis and cancer prognosis
  • Traffic Prediction and Management Techniques
  • RNA modifications and cancer
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Atmospheric and Environmental Gas Dynamics
  • Cancer-related molecular mechanisms research
  • Liver Disease Diagnosis and Treatment
  • Sentiment Analysis and Opinion Mining
  • Microstructure and mechanical properties
  • Microstructure and Mechanical Properties of Steels
  • Coronary Interventions and Diagnostics
  • Biomarkers in Disease Mechanisms
  • Medicinal Plants and Bioactive Compounds
  • Research in Cotton Cultivation
  • Machine Learning and ELM
  • Plant Water Relations and Carbon Dynamics
  • Congenital Ear and Nasal Anomalies
  • Facial Rejuvenation and Surgery Techniques
  • Ear and Head Tumors

Lanzhou University
2025

Gansu Provincial Hospital
2025

The Affiliated Yongchuan Hospital of Chongqing Medical University
2025

Chongqing Medical University
2025

Changzhou No.2 People's Hospital
2023-2024

Nanjing Medical University
2023-2024

First Affiliated Hospital of Bengbu Medical College
2023-2024

Bengbu Medical College
2023-2024

Jiangsu Yonggang Group (China)
2024

Gansu Provincial Maternal and Child Health Hospital
2024

Combining information from multispectral images into a fused image is informative and beneficial for human or machine perception. Currently, multiple photodetectors with different response bands are used, which require complicated algorithms systems to solve the pixel position mismatch problem. An ideal solution would be pixel-level fusion, involves using same photodetector circumventing Here we presented potential of fusion utilizing colloidal quantum dots photodiode array, broadband range...

10.1038/s41467-023-40620-3 article EN cc-by Nature Communications 2023-09-02

Solution-processed colloidal quantum dot (CQD) photodiodes are compatible for monolithic integration with silicon-based readout circuitry, enabling ultrahigh resolution and ultralow cost infrared imagers. However, top-illuminated CQD longer imaging suffer from mismatched energy band alignment between narrow-bandgap CQDs the electron transport layer. In this work, we designed a new structure by replacing sputtered ZnO layer SnO2 atomic deposition. Benefiting matched improved heterogeneous...

10.1021/acs.nanolett.3c01391 article EN Nano Letters 2023-07-11

Lung cancer, ranking second globally in both incidence and high mortality among common malignant tumors, presents a significant challenge with frequent occurrences of drug resistance despite the continuous emergence novel therapeutic agents. This exacerbates disease progression, tumor recurrence, ultimately leads to poor prognosis. Beyond acquired due genetic mutations, mounting evidence suggests critical role epigenetic mechanisms this process. Numerous studies have indicated abnormal...

10.3389/fonc.2024.1376916 article EN cc-by Frontiers in Oncology 2024-03-08

Plankton is an important component of a healthy shallow lake aquatic system, and the diversity stability its community structure are impacted by numerous environmental factors. However, knowledge about relative importance these factors limited. This study presents case conducted in semi-arid, eutrophic lakes China to evaluate physical, chemical, nutritional characteristics water quality light effects on spatiotemporal distributions plankton communities. The findings showed that was least...

10.1016/j.ecolind.2022.109560 article EN cc-by-nc-nd Ecological Indicators 2022-10-10

Abstract Conventional electrospinning produces nanofibers with smooth surfaces that limit biomineralization ability. To overcome this disadvantage, we fabricated a tetramethylpyrazine (TMP)-loaded matrix-mimicking in PCL/Gelatin composite electrospun membranes bubble-shaped nanofibrous structures. (PG), containing biomineralized hydroxyapatite (HA) (PGH), and HA loaded TMP (PGHT) were tested. In vitro results indicated the surface increased roughness of promoted mineralization. Furthermore,...

10.1186/s12951-023-02155-z article EN cc-by Journal of Nanobiotechnology 2023-11-14

Lung cancer still ranks first in the mortality rate of cancer. Uric acid is a product purine metabolism humans. Its presence serum controversial; some say that its high levels have protective effect against tumors, others opposite, is, increase risk Therefore, aim this study was to investigate potential causal association between uric and lung

10.1186/s12885-024-12576-0 article EN cc-by BMC Cancer 2024-07-05

Adipose tissue is endocrine organ that responds by secreting numerous hormones regulate metabolism in skeletal muscle and the liver. The aim of this study was to compare levels spexin adiponectin patients with non-alcoholic fatty liver evaluate relationship between circulating adipocytokines insulin resistance. Two groups subjects were evaluated: 41 (age 35.17 ​± ​12.29 year, BMI 30.97 ​2.75 ​kg/m2) 38 normal controls 38.47 ​11.63 22.83 ​3.00 ​kg/m2). Plasma concentrations determined using...

10.1016/j.plabm.2021.e00207 article EN cc-by-nc-nd Practical Laboratory Medicine 2021-02-07

Background: Lung adenocarcinoma ranks as the second most widespread form of cancer globally, accompanied by a significant mortality rate.Several studies have shown that T cell exhaustion is associated with immunotherapy tumours.Consequently, it essential to comprehend possible impact on tumor microenvironment.The purpose this research was create TEX-based model would use single-cell RNA-seq (scRNA-seq) and bulk-RNA sequencing explore new possibilities for assessing prognosis...

10.7150/jca.92839 article EN cc-by-nc Journal of Cancer 2024-01-01

Background: Salidroside (SAL) is the most effective component of Rhodiola rosea , a traditional Chinese medicine. Cryptotanshinone (CT) main fat-soluble extract Salvia miltiorrhiza exhibiting considerable potential for application in osteogenesis. Herein, polycaprolactone/gelatin nanofiber membrane loaded with CT and SAL (PSGC membrane) was successfully fabricated via coaxial electrospinning characterized. Methods Results: This capable sustained controlled drug release employed this study....

10.2147/ijn.s461141 article EN cc-by-nc International Journal of Nanomedicine 2024-06-01

tsRNAs are novel small non-coding RNAs that play important regulatory roles in gene expression, translation, transcription, and epigenetic modification through proteins or mRNAs may be therapeutic targets for certain diseases. The etiology of non-syndromic cleft palate-only is complex the pathogenesis poorly understood, its development. patients with simple palate were compared healthy individuals using RNA microarray, bioinformatic analysis, quantitative real-time transcription polymerase...

10.1186/s12903-025-05661-8 article EN cc-by-nc-nd BMC Oral Health 2025-02-26

Abstract Objective The aim of this paper is to investigate the effect long noncoding RNA (lncRNA) MIR100HG on proliferation and metastasis lung cancer cells by mediating microRNA (miR)−5590‐3p/DCBLD2 axis. Methods levels MIR100HG, miR‐5590‐3p, DCBLD2 in tissues were detected quantitative reverse‐transcription polymerase chain reaction, protein level was assessed Western blot. Effects or miR‐5590‐3p proliferation, migration, invasion Cell Counting Kit‐8, colony formation, Transwell assays....

10.1002/iid3.1223 article EN cc-by Immunity Inflammation and Disease 2024-04-01

Abstract Background PD-L1 overexpression is commonly observed in various malignancies and strongly correlated with poor prognoses for cancer patients. Moreover, has been shown to play a significant role promoting angiogenesis epithelial-mesenchymal transition (EMT) processes across different types. Methods The relationship between vasculogenic mimicry as well was explored by bioinformatics approach immunohistochemistry. functions of regulating the expression ZEB1 EMT process were assessed...

10.1186/s12885-024-12390-8 article EN cc-by BMC Cancer 2024-05-23

The systemic inflammatory response may influence the occurrence of postoperative complications. This study aimed to evaluate predictive potential combining platelet count and neutrophil-to-lymphocyte ratio (COP-NLR) for esophagogastric anastomotic leak (AL) following esophageal cancer surgery. We enrolled patients who developed AL after radical surgery those did not develop at First Affiliated Hospital Chongqing Medical University, China, from June 2019 February 2022. analyzed correlation...

10.7759/cureus.81589 article EN Cureus 2025-04-01

(1) Background: Primary intraspinal tumors account for 2–15% of all central nervous system (CNS) tumors. Most are benign, and about 40% them occur intradurally, which early surgery is the preferred treatment. Laminectomy with pedicle screw fixation conventional surgical However, laminectomy likely to reduce spinal range motion (ROM), many other complications, although it can maintain stability spine. The aim this study determine whether laminoplasty as a new approach thoracic lumbar...

10.3390/jcm12010355 article EN Journal of Clinical Medicine 2023-01-02

Solution-processed colloidal quantum dots (CQDs) photodiodes are compatible for monolithic integration with silicon-based readout circuit, enabling high-performance and low-cost infrared imaging. However, operation stability of CQDs has rarely been explored, which is one the main obstacles imaging commercialization. Here, we reveal that performance deterioration under strong electric field at high temperature mainly attributed to ion migration in film, clearly clarified by aging...

10.1021/acsphotonics.2c01634 article EN ACS Photonics 2022-12-29

Background: Lung adenocarcinoma (LUAD) is one of the leading causes cancer-related mortality. Lysophosphatidylglycerol acyltransferase (LPGAT1) regulates biosynthesis triacylglycerol, which essential for maintaining phospholipid homeostasis and modulating structural integrity mitochondrial membranes. LPGAT1 has been demonstrated to be differentially expressed in normal lung tissue LUAD tissues, can serve as a metabolically relevant gene with potential prognostic value. However, role still...

10.31083/j.fbl2805089 article EN cc-by Frontiers in Bioscience-Landmark 2023-05-11
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