A5113628621- Genetic Associations and Epidemiology
- Renal Transplantation Outcomes and Treatments
- Nuclear Receptors and Signaling
- Genetics and Neurodevelopmental Disorders
- Peptidase Inhibition and Analysis
- Pharmacogenetics and Drug Metabolism
- Signaling Pathways in Disease
- Cancer Mechanisms and Therapy
- Retinal Diseases and Treatments
- Glutathione Transferases and Polymorphisms
- Antibiotics Pharmacokinetics and Efficacy
- Retinal Imaging and Analysis
- Drug Transport and Resistance Mechanisms
- Antioxidant Activity and Oxidative Stress
- Carcinogens and Genotoxicity Assessment
Sichuan University
2025
West China Hospital of Sichuan University
2025
Huashan Hospital
2020
Fudan University
2020
Xi'an Honghui Hospital
2016
Shenzhen University
2014
XinHua Hospital
2013
Objective To compare different doses and dosing regimens of RC28-E, a novel bispecific antibody that simultaneously binds vascular endothelial growth factor-A (VEGF-A) fibroblast factor-2 (FGF-2), with conbercept in patients diabetic macular edema (DME). Design Prospective, randomised, active comparator-controlled, open-label, multicentre, phase 2 clinical trial.cente Participants The trial enrolled aged 18 years or older centre-involving DME, best-corrected visual acuity (BCVA) 73 to 24...
To clarify the association of rs11196218 polymorphism in transcription factor 7-like 2 (TCF7L2) and type diabetes mellitus (T2DM) Asian population by a case–control study meta-analysis. In study, 1842 patients with T2DM 7777 normal glucose-tolerant controls Henan province China were genotyped for TCF7L2 PCR–ligase detection reaction. We used allele, co-dominant, dominant recessive models to evaluate risk performed meta-analysis results different genetic previous studies current study. The AG...
Abstract Aim Ciclosporin (CsA) has been shown to follow nonlinear pharmacokinetics in renal transplant recipients who received Neoral-based triple immunosuppressive therapy. Some of these properties have not fully considered population pharmacokinetic (popPK) analysis. Therefore, the aim this study was determine potential influence nonlinearity and functional forms covariates on model predictability. Methods A total 2969 CsA whole-blood measurements, including 1328 pre-dose 1641 2-h...