Xiao‐Dong Yin

ORCID: 0000-0002-2657-2379
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About
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Research Areas
  • Medical Imaging and Analysis
  • Estrogen and related hormone effects
  • Natural product bioactivities and synthesis
  • Circular RNAs in diseases
  • Endometriosis Research and Treatment
  • Cancer-related molecular mechanisms research
  • Systemic Sclerosis and Related Diseases
  • Bone fractures and treatments
  • Plant-derived Lignans Synthesis and Bioactivity
  • Mycobacterium research and diagnosis
  • Flavonoids in Medical Research
  • Retinoids in leukemia and cellular processes
  • Phytoestrogen effects and research
  • Cancer-related gene regulation
  • Zoonotic diseases and public health
  • Synthesis and biological activity
  • Simulation-Based Education in Healthcare
  • Nanoparticle-Based Drug Delivery
  • HER2/EGFR in Cancer Research
  • Trauma Management and Diagnosis
  • Vitamin D Research Studies
  • Sphingolipid Metabolism and Signaling
  • Animal Disease Management and Epidemiology
  • Autophagy in Disease and Therapy
  • Bioactive natural compounds

Wangjing Hospital of China Academy of Chinese Medical Sciences
2024-2025

Chinese Academy of Medical Sciences & Peking Union Medical College
2024-2025

Nanjing Medical University
2019-2022

Suzhou Municipal Hospital
2019-2022

Anhui Medical University
2019-2021

Changhai Hospital
2021

Second Military Medical University
2021

Binzhou People's Hospital
2016

Chengdu Fifth People's Hospital
2014

Union Hospital
2012

One of the main problems in B cell lymphoma treatment is severe adverse effects and low therapeutic efficacy resulting from systemic chemotherapy. A pH-sensitive controlled drug release system based on mesoporous silica nanoparticles was constructed for targeted delivery to tumor cells reduce toxicity improve efficacy. In this study, doxorubicin (DOX) filled into mesopores functional MSNs (DMSNs). Furthermore, rituximab introduced as motif DMSNs using an avidin-biotin bridging method...

10.1186/s13046-017-0492-6 article EN cc-by Journal of Experimental & Clinical Cancer Research 2017-02-06

To explore the accuracy of human-computer interaction software in identifying and locating type C1 distal radius fractures. Based on relevant inclusion exclusion criteria, 14 cases fractures between September 2023 March 2024 were retrospectively analyzed, comprising 3 males 11 females(aged from 27 to 82 years). The data assigned randomized identifiers. A senior orthopedic physician reviewed films measured ulnar deviation angle, radial height, palmar inclination intra-articular step, gap for...

10.12200/j.issn.1003-0034.20240601 article EN PubMed 2025-01-25

Pancreatic cancer is one of the most lethal malignancies all types due to lack early symptoms and its resistance conventional therapy. In our previous study, we have shown that v‑ets erythroblastosis virus E26 oncogene homolog‑1 (ETS‑1) promote cell migration invasion in pancreatic cells. However, function ETS‑1 regulation glycolysis autophagy during progression has not been defined yet. this sought identify potential role for silencing reducing expression glucose transporter‑1 (GLUT‑1)...

10.3892/ijo.2016.3770 article EN International Journal of Oncology 2016-11-16

The role of Helicobacter pylori status and serum zinc value in gastric disease patients healthy controls were investigated. Cases used this work 45 cancer patients, 44 with peptic ulcers, 52 suffering gastritis 64 controls, all diagnosed histologically the undergoing medical checkups. levels Zn determined by 13C-urea breath test flame atomic absorption spectrophotometer, respectively. Our study showed that infection has no change gastritis, ulcer group, on contrast, significantly reduced...

10.7314/apjcp.2012.13.10.5043 article EN cc-by Asian Pacific Journal of Cancer Prevention 2012-10-31

Background and objectives: Vitexin is a natural flavonoid glycoside mainly extracted from the leaves of vitex, which has variety physiological activities. For example, vitexin antitumor anti-inflammation activities, it can also promote blood circulation in body. However, function mechanism nasopharyngeal carcinoma (NPC) are still unclear. Materials methods: Cell Counting Kit-8 assay cell cycle analysis were performed to examine survival response vitexin. Immunoblotting was used analyze...

10.2147/ott.s210077 article EN OncoTargets and Therapy 2019-06-01

Background: The most recent international guidelines recommended support training of chest compression (CC) using feedback devices. This study aimed to compare the efficacy a simplified trainer with traditional cardiopulmonary resuscitation (CPR) simulator in CPR training. Methods: A total 60 soldiers were randomly allocated into three groups equally, trained external cardiac massage (ECM) named Soul Sheath TM (SS) (SS group), Resusci Anne manikin (RA or simulation instructor feedback,...

10.3389/fpubh.2021.675487 article EN cc-by Frontiers in Public Health 2021-10-14

2-Amino-2-[2-(4-octylphenyl)ethyl] propane-1,3-diol hydrochloride (FTY720) is a novel agent with protective effect on several markers of liver injury. It chemical substance derived by modifying myriocin from the ascomycete Isaria sinclairii. has been reported that FTY720 able to treat autoimmune encephalomyelitis, renal cancer, asthma, and multiple sclerosis. More potent clinical applications need be investigated.The aim this study was evaluate experimental injury investigate possible...

10.1016/j.curtheres.2012.07.001 article EN publisher-specific-oa Current Therapeutic Research 2012-08-27

To explore weight-bearing stability of Pilon fracture fixed by external fixator. Six ankle bone models (right side) and 4 pairs (8 cadaver specimens) were selected. model was prepared using the preset osteotomy line based on Ruedi Allgower type. built a minimally invasive osteotomy. After specimen with fixator, axial load carried out mechanical loading machine. Axial loads 150, 300 450 N applied to model, displacements fibula blocks, lateral tibia blocks medial in three-dimensional space (X,...

10.12200/j.issn.1003-0034.20230702 article EN PubMed 2024-12-25

NIP patients (n = 106) admitted between January 2020 and March 2021 were selected grouped as follows according to the random number table method: a dissection group treated with dynamical-system surgery under nasal endoscope an ablation LTPRA. The clinical curative effects of two procedures compared, related indexes (operation time (OT), intraoperative blood loss (IBL), length stay (LOS)) postoperative adverse reactions (ARs) counted. In addition, fasting venous samples collected before...

10.1155/2022/9618193 article EN Computational and Mathematical Methods in Medicine 2022-10-09

Objectives To explore the significance of relative level eIF4E in monitoring therapeutic effect acute myeloid leukemia (AML), by comparing AML patients who received initial treatment, complete remission (CR), non-remission and relapse. Methods From August 2012 to May 2014, a total 152 treatment Department Hematology Sichuan Provincial People's Hospital were enrolled this study, as study group. According France-America-Britain (FAB) assistance typing method, these included 18 cases M1...

10.3760/cma.j.issn.1673-419x.2015.01.002 article EN Guoji shuxue ji xueyexue zazhi 2015-01-20

Objective s To analysis the expression difference of eIF4E in bone marrow between acute myeloid leukemia(AML)and non-tumor patient, before and after induction therapy, different subtypes AML, to explore relation other molecular biology abnormalities AML. Methods The specimens newly diagnosed AML control patients were collected. The level was detected by RT-PCR. Results The positive rate 65.2 %(101/155)in AML. turned negative 12 patients(17.6 %)who got complete remission therapy....

10.3760/cma.j.issn.1009-9921.2015.03.011 article EN Baixuebing linbaliu 2015-03-25
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