A5070573478- Nerve injury and regeneration
- Neurogenesis and neuroplasticity mechanisms
- Neuropeptides and Animal Physiology
- Regulation of Appetite and Obesity
- Nitric Oxide and Endothelin Effects
- Meat and Animal Product Quality
- Sperm and Testicular Function
- Axon Guidance and Neuronal Signaling
- Animal Nutrition and Physiology
- MicroRNA in disease regulation
- Biochemical Analysis and Sensing Techniques
- Reproductive Physiology in Livestock
- Fatty Acid Research and Health
- Barrier Structure and Function Studies
- Biochemical effects in animals
- Aquaculture Nutrition and Growth
- Rabbits: Nutrition, Reproduction, Health
- Adipose Tissue and Metabolism
- Sleep and Wakefulness Research
- Silk-based biomaterials and applications
- Aquaculture disease management and microbiota
- Congenital gastrointestinal and neural anomalies
- Protein Hydrolysis and Bioactive Peptides
- Nuts composition and effects
- Cancer, Lipids, and Metabolism
University of Naples Federico II
2012-2023
Federico II University Hospital
2013-2023
Ceinge Biotecnologie Avanzate (Italy)
2005
Astragalus membranaceus (Fisch.) Bunge root is used as herbal medicine for its immunomodulating activities in Chinese medicine. Recently, beneficial properties of A. on allergic diseases have been proposed. Here we investigated the role a commercial extract membranaceus, standardized to 16% polysaccharides, regulating immune-inflammatory response vitro and vivo therapeutic application asthma. inhibited prostaglandin E2 leukotriene C4 production stimulated J774 peritoneal macrophages,...
This study aimed to examine the impact of different surface properties poly(lactic-co-glycolic) acid (PLGA) nanoparticles (P NPs) and PLGA-Poloxamer (PP on their in vivo biodistribution. For this purpose, NPs were formulated via nanoprecipitation loaded with diphenylhexatriene (DPH), a fluorescent dye. The obtained underwent comprehensive characterization, encompassing morphology, technological attributes, DPH release rate, thermodynamic properties. produced then administered wild-type mice...
This study evaluated the effects of supplementing with natural functional feed on plasma fatty acid profile lactating Italian Holstein-Friesian dairy cows. Thirty cows in mid-lactation received olive extract PHENOFEED DRY (500 mg/cow/day) which mainly comprises hydroxytyrosol, tyrosol and verbascoside. The total content polyphenols antioxidant power standard feed, enriched pure was respectively by Folin-Ciocalteu DPPH assay, a characterization HPLC-UV (High-Performance Liquid...
Among the most-used fish species in aquaculture is Nile tilapia, due to its rapid growth rate and adaptation a wide range of farming conditions. A careful description morphology digestive tract, particularly esophagus stomach, allows better understanding relationship between structure function. Combining scanning light microscopy we highlighted presence five different zones stomach (1: esophagus-gastric lumen passage; 2: descending glandular portion; 3: fundic 4: ascending 5: gastric-pyloric...
This study provides a general approach to the presence and possible role of orexins their receptors in gut (three gastric chambers intestine) confined environment bottlenose dolphin. The expression prepro-orexin, orexin A B 1 2 were investigated by single immunostaining western blot analysis. co-localization vasoactive intestinal peptide receptor enteric nervous system was examined double immunostaining. Also, concentration measured plasma samples assess diurnal variation level this species....
The forestomach plays an important role in the digestion physiology of ruminants. aim this study is to clarify morpho-functional mucosa each three compartments domestic ruminants species, viz cattle, buffalo and sheep, by means structural, histochemical immunocytochemical methods, including transmission electron microscopy, light microscopy scanning microscopy. These methods were chosen demonstrate indirect evidence for presence nitric oxide (NO) employing NADPHd synthase I (NOS I). various...
Nerve growth factor (NGF), brain derived neurotrophic (BDNF) and neurotrophin-3 (NT-3) are members of the neurotrophin family, which is involved in differentiation, growth, repair, plasticity maintenance many neuronal populations. They act through three tyrosin-kinase (Trk) specific receptors: NGF bind to TrkA, BDNF TrkB NT3 TrkC. Despite increasing evidence regarding presence their receptors vertebrate species, amphibians there very few data concerning them. Thus, aim this study was extend...
Chronic myeloid leukemia (CML) is a myeloproliferative disease that activates multiple signaling pathways, causing cells to produce higher levels of reactive oxygen species (ROS). Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOXs) are major generator ROS in leukemia, and marine natural products have shown promising activities for the treatment hematopoietic malignancies. In present study, we investigated effect microalga Skeletonema marinoi (S.M.), ubiquitous diatom forms...
Glial cell line-derived neurotrophic factor (GDNF) is a potent trophic for several types of neurons in the central and peripheral nervous systems. The biological activity GDNF mediated by multicomponent receptor complex that includes common transmembrane signaling component (the rearranged during transfection (RET) proto-oncogene product, tyrosine kinase receptor) as well family alpha (GFRalpha) subunit, high-affinity glycosyl phosphatidylinositol (GPI)-linked binding element. Among four...
Nesfatin-1(Nesf-1) is an anorexigenic peptide involved in the regulation of homeostatic feeding. Nesf-1 expressed central nervous system and other organs, including pancreas, where it promotes release insulin from β-cells. This raises possibility that Nesf-1dysfunction could be metabolic disorders, particularly type 2 diabetes mellitus (T2D). Recently, has been discovered dolphins can a natural animal model fully replicates human T2D, due to its prolonged glucose tolerance curve maintanaince...