A5055306895- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Cardiac Valve Diseases and Treatments
- Cardiovascular and exercise physiology
- Neonatal Respiratory Health Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- RNA modifications and cancer
- Infrared Thermography in Medicine
- MicroRNA in disease regulation
- Connective tissue disorders research
- Dysphagia Assessment and Management
- Obstructive Sleep Apnea Research
- Coronary Interventions and Diagnostics
- Tribology and Lubrication Engineering
- Calpain Protease Function and Regulation
- Pulmonary Hypertension Research and Treatments
- Congenital Diaphragmatic Hernia Studies
- Aortic Disease and Treatment Approaches
- Heart Rate Variability and Autonomic Control
- Healthcare and Environmental Waste Management
- Sarcoidosis and Beryllium Toxicity Research
- Cardiac Fibrosis and Remodeling
- Cardiac Arrhythmias and Treatments
- Long-Term Effects of COVID-19
- Medical Coding and Health Information
AVEO Oncology (United States)
2024
Sanofi (United States)
2024
Gulu Hospital
2024
Temple University
2021-2024
Midas Multispeciality Hospital
2013-2022
Jamia Millia Islamia
2020
Texas Tech University
2017-2019
Mobility Outreach International
2018
Southend University Hospital NHS Foundation Trust
2011-2012
Papworth Hospital NHS Foundation Trust
2009
Since most of the body's extracellular matrix (ECM) is composed collagen and elastin, we believe choice these materials key for future promise tissue engineering. Once it known how elastin content ECM guides cellular behavior (in 2D or 3D), one will be able to harness power collagen-elastin microenvironments design engineer stimuli-responsive tissues. Moreover, implementation such matrices promote endothelial-mesenchymal transition primary endothelial cells constitutes a powerful tool 3D...
Background.Recent research shows that pulmonary rehabilitation (PR) programmes in patients with acute exacerbation of chronic obstructive disease (AECOPD), reduced dyspnoea, improved exercise capacity, and prevented occurrence further exacerbations.Objective.To evaluate the utility a 3-week PR programme AECOPD.Methods.Patients admitted AECOPD, following clinical stabilisation respiratroy intensive care unit (RICU), were alternately assigned to intervention (n=15); control groups (n=15),...
Lung alveolar type 2 (AT2) cells are progenitors for 1 (AT1) cells. Although many factors regulate AT2 cell plasticity, the role of mitochondrial calcium (mCa2+) uptake in controlling remains unclear. We previously identified that miR-302 family supports lung epithelial progenitor proliferation and less differentiated phenotypes during development. Here, we report a sustained elevation adult decreases AT2-to-AT1 differentiation Streptococcus pneumoniae–induced injury repair. targets...
Background Interstitial lung disease (ILD) encompasses a diverse group of chronic conditions which is often characterized by inspiratory muscle weakness (IMW). Despite the potential importance dysfunction in ILD, effect training (IMT) added to pulmonary rehabilitation (PR) ILD largely remains unknown.Objective The primary objective present study was evaluate benefits IMT PR on strength and secondary objectives were assess its effects functional capacity, health-related quality life (HRQoL),...
To determine the reliability, validity, and responsiveness of incremental shuttle walk test (ISWT) in patients with interstitial lung disease (ILD).This was a cross-sectional longitudinal study. Patients (n = 27, 10 males; mean age ± SD, 61 9.8 y) ILD any etiology, who participated an outpatient pulmonary rehabilitation (PR) program, were recruited. Reliability determined by comparing distance covered meters between ISWT-1 ISWT-2. Validity assessed correlating ISWT-1, maximum oxygen...
We sought to evaluate the effectiveness of six weeks pulmonary rehabilitation (PR) in patients with asthma-chronic obstructive disease (COPD) overlap syndrome (ACOS).We enrolled 28 ACOS. Fourteen were randomly allocated PR group, which comprised supervised endurance training, resistance breathing exercises, self management, and education. The other 14 control who asked continue their usual routine strategies for weeks. All assessed at baseline after using minute walk test (6MWT), St George...
Valvular endothelial cells line the outer layer of heart valves and can withstand shear forces caused by blood flow. In contrast to vascular cells, there is limited amount research over valvular cells. For this reason, exact physiologic behavior unclear. Prior studies have concluded that align perpendicularly direction flow, while parallel Other suggested different ranges stress uniquely impact The goal study was characterize response cell under types, magnitudes, durations stress. work,...
Background: Pulmonary embolism (PE) presents great acute danger and its chronic effects on cardiovascular organization is an important, however investigated aspect. People who survive PE subjected to higher vulnerability develop long-term diseases including heart failure as well pulmonary hypertension also exhibit hospital admission rates. It therefore important grasp these risks in effort get the best out of treatment patients. Objectives: The current meta-analysis has been designed look at...
In patients presenting with post-malarial anemia following intravenous artesunate treatment, post-artesunate delayed hemolysis should be considered in the differential diagnosis, even endemic settings. Close monitoring for signs of previously treated severe malaria, regardless their malaria exposure history or geographic location is crucial.
The significance of alveolar epithelial type 2 (AT2) cell proliferation for lung homeostasis and regeneration after injury has been widely accepted. However, the heterogeneity AT2 population capacity remains disputed. By single-cell RNA sequencing genetic lineage labeling using Ki67 knock-in mouse model, we map all proliferative cells in homeostatic regenerating murine lungs induced by Streptococcus pneumoniae infection. displays a unique transcriptional program, which is regulated...
Alveolar epithelial regeneration depends on the activity of resident quiescent progenitor cells. type II (AT2) cells are known as alveolar They exit state, proliferate rapidly in response to injury and differentiate into I (AT1) regenerate damaged epithelium. Although AT2 cell plasticity has been a very intense field research, role CD8 T their released cytokine IFN-γ, regulating repair after remains largely unknown.
Background: Eccentric exercise may be considered as an attractive alternative to conventional in pulmonary rehabilitation (PR) for patients with chronic obstructive disease (COPD). However, due muscle damage associated eccentric exercise, there has been reluctance using this form PR.Objective: The aim of the present study was investigate effect on markers COPD.Methods: We analyzed 14 moderate-severe COPD and age-matched healthy controls. Both groups performed submaximal elbow flexors. Muscle...
To determine diagnostic validity of cardiopulmonary exercise testing (CPX) parameters for detecting pulmonary hypertension (PH) in patients with chronic obstructive disease (COPD) and to investigate association between CPX indices PH.This cross-sectional study enrolled 48 moderate very severe COPD whom PH was confirmed by echocardiography. Symptom-limited performed using an incremental protocol. Relevant were derived tested their ability diagnosing PH. Logistic regression applied examine the...
Abstract Background Cardiomyocytes proliferate rapidly during fetal life but lose their ability of proliferation soon after birth. However, before terminal withdrawal from the cell cycle, cardiomyocytes undergo another round cycle early postnatal in mice. While a transient wave increased DNA synthesis cardiomyocyte has been observed mouse hearts, molecular mechanisms describing re-entry remain poorly understood. Atrial and B-type natriuretic peptides (ANP BNP) are abundantly expressed...
Objective: The purpose of the study was to identify clinical differences in patients with acute urticaria and/or angioedema receiving various treatment regimes emergency department Lady Reading Hospital, Peshawar. Particularly, it compared modern antihistamine therapy corticosteroids as an analogue routine antihistamines regard rate symptom improvement, relapse, and hospitalisation. Methods: This a cross-sectional descriptive involving 542 angioedema. Patients were categorised into two...