A5005166456- Breastfeeding Practices and Influences
- Child and Adolescent Health
- Celiac Disease Research and Management
- Food Security and Health in Diverse Populations
- Natural Language Processing Techniques
- Child Nutrition and Feeding Issues
- Migration, Health and Trauma
- Infant Development and Preterm Care
- Microscopic Colitis
- Gastrointestinal disorders and treatments
- Endometriosis Research and Treatment
- Helicobacter pylori-related gastroenterology studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cancer-related molecular mechanisms research
- Child Nutrition and Water Access
- Obesity, Physical Activity, Diet
- Gynecological conditions and treatments
- Angiogenesis and VEGF in Cancer
- Mobile Health and mHealth Applications
- Uterine Myomas and Treatments
- Advanced Breast Cancer Therapies
- Medication Adherence and Compliance
- Bone and Dental Protein Studies
- SARS-CoV-2 and COVID-19 Research
- Gastrointestinal Bleeding Diagnosis and Treatment
Boston Children's Hospital
2021-2024
Apple (United States)
2024
Harvard University
2010-2023
Huazhong University of Science and Technology
2021-2022
Union Hospital
2022
Second Hospital of Hebei Medical University
2019-2021
Sun Yat-sen University
2021
Sun Yat-sen University Cancer Center
2021
Hebei Medical University
2019-2021
Boston Children's Museum
2021
In this work, we discuss building performant Multimodal Large Language Models (MLLMs). particular, study the importance of various architecture components and data choices. Through careful comprehensive ablations image encoder, vision language connector, pre-training choices, identified several crucial design lessons. For example, demonstrate that for large-scale multimodal using a mix image-caption, interleaved image-text, text-only is achieving state-of-the-art (SOTA) few-shot results...
While MLLMs perform well on perceptual tasks, they lack precise multimodal alignment, limiting performance. To address this challenge, we propose Vision Dynamic Embedding-Guided Pretraining (VDEP), a hybrid autoregressive training paradigm for MLLMs. Utilizing dynamic embeddings from the MLP following visual encoder, approach supervises image hidden states and integrates tokens into training. Existing primarily focused recovering information textual inputs, often neglecting effective...
Nature frequently utilizes opposing factors to create a stable activator gradient robustly control pattern formation. This study employs biomimicry approach, by delivery of both angiogenic and antiangiogenic from spatially restricted zones synthetic polymer achieve temporally in vivo. The simultaneous release the two separated agents leads sharp region that is sustained over 3 wk. Further, contradictory action level proangiogenic stimulation this region, spite significant variations...
BACKGROUND:Dental pulp cells (DPCs) play vital roles in the recovery of dental tissue. Concentrated growth factor (CGF) can promote proliferation and mineralization various cells. However, functions CGF on DPCs tissue are unclear. The object our study was to identify vitro assess effects direct capping vivo. MATERIAL AND METHODS:We performed CCK-8 Transwell assay detect migration activity DPCs. Alizarin Red staining examine mineralized nodules. Alkaline phosphatase test used measure capacity...
The limb-bud and heart (LBH) gene was reported to suppress nasopharyngeal carcinoma (NPC) progression in our previous study. Distant metastasis predominantly accounts for the unsatisfactory prognosis of NPC treatment, which epithelial-mesenchymal transition (EMT) tumor angiogenesis are great significance. roles exosomes mediating have been highlighted recent researches, attempts made explore clinical application exosomes. Here we investigated function LBH exosomes, its potential mechanism....
Gluten-free (GF) foods are generally costlier than their gluten-containing counterparts. We conducted an anonymous electronic survey to assess food insecurity in households with a child on prescribed GF diet and how this relates adherence during the COVID-19 pandemic. The proportion of who screened positive using Hunger Vital Sign was similar national rates (19%-24%). Approximately 5% families secure reported insecurity. Parent-reported intentional gluten consumption due limited availability...
The American Academy of Pediatrics (AAP) and North Society for Pediatric Gastroenterology, Hepatology Nutrition recommend either exclusively breastfeeding at least 6 months or an u.S. Food Drug Administration-reviewed infant formula donor breast milk from established bank as alternatives. purpose this study was to establish the prevalence contemporary feeding practices such informal human sharing, imported European formula, toddler homemade gain insight into parental reasoning their...
Ganoderma lucidum polysaccharide (GLP) is a well‑known traditional Chinese medicine, known for its anti‑cancer and immunomodulatory properties. The present study aims to investigate whether GLP has therapeutic effect on hepatocellular carcinoma (HCC) cells exposed radiation. Immunofluorescence was used detect the nuclei, protein expression measured by western blot analysis flow cytometry rate of cell apoptosis. treatment demonstrated enhance radiation‑induced growth inhibition apoptotic...
Microalbuminuria was much more common among obese individuals indicating a probable association with obesity. However, of microalbuminuria interaction between obesity and central has not yet been studied.A cross-sectional study conducted in 2889 general population aged ≥ 30 years. Obesity defined as body mass index 28.0 kg/m2 waist-to-hip ratio 0.85 for females 0.90 males. Both additive multipliable interactions on elevated urinary albumin-to-creatinine (UACR) were evaluated.After...
Infant formula in the United States is highly regulated. The American Academy of Pediatrics (AAP) has reported concerns over use non-Food and Drug Administration (FDA)-registered imported infant formulas. purpose this study to identify Internet purchased recommended European formulas compare them with FDA labeling nutrient requirements.We searched "European formulas" Google DuckDuckGo vendors blogs discussing these determine most frequently brands. We then compared identified formula's label...
Chronic obstructive pulmonary disease (COPD) has recently become the third leading cause of death following heart and cancer. Acute exacerbation COPD (AECOPD) can be prevented by early detection deterioration timely treatment, which effectively lower severity prevent hospitalization.[1] Remote patient monitoring (RPM) is essential for inpatient outpatient care settings [Supplementary Figure 1, https://links.lww.com/CM9/A562]. Artificial intelligence (AI) technologies implemented in RPM help...
<italic>Gynostrmma pentaphyllum</italic>seed oil (GPSO), extracted from<italic>G. pentaphyllum</italic>seeds, is rich in conjugated linolenic acid, which a special fatty acid consisting of<italic>cis</italic>-9,<italic>trans</italic>-11,<italic>trans</italic>-13 isomers.
We present foundation language models developed to power Apple Intelligence features, including a ~3 billion parameter model designed run efficiently on devices and large server-based for Private Cloud Compute. These are perform wide range of tasks efficiently, accurately, responsibly. This report describes the architecture, data used train model, training process, how optimized inference, evaluation results. highlight our focus Responsible AI principles applied throughout development.
Lifelong adherence to a gluten-free diet (GFD) is the primary treatment of celiac disease (CeD), gluten-driven enteropathy. Concerns have been raised about increased exposure arsenic from GFD because rice, which naturally bioaccumulates arsenic, commonly used as substitute for gluten-containing grains such wheat. We hypothesize that increases in newly diagnosed children with CeD after they adopt GFD.
Objective: European Society for Pediatric Gastroenterology, Hepatology and Nutrition the American Academy of Pediatrics state that young child formula (YCF) is not considered necessary healthy children. Despite these recommendations, YCF accounts approximately 13% overall sales. Five percent infants less than 1 year age in United States are being fed YCF. The purpose this study to identify most Internet recommended encountered determine if they meet nutritional recommendations use children...
Cancer is a major public health issue in China, and effective anticancer drugs remain huge unmet need. Generic have long been the main products of pharmaceutical companies China. In this decade, research on development innovative has greatly advanced thanks to policy reforms economic growth. Five - anlotinib, pyrotinib, fruquintinib, sintilimab, toripalimab that were developed by Chinese domestic approved National Medical Products Administration (NMPA) China 2018. Several novel such as...
ABSTRACT Objectives: While the use of telemedicine has accelerated significantly with recent pandemic, it also magnified disparities in access to telemedicine. This study aims look at utilization patterns within a large pediatric gastroenterology practice. Methods: A retrospective ambulatory care visits Yale‐New Haven Hospital's practice during peak expansion program was conducted. Zip code−level socioeconomic data were obtained using Distressed Communities Index. multivariate logistic...
Surgical sterilization is a common method of contraception. There have been few studies evaluating the effect obesity on procedural complications with either laparoscopic or hysteroscopic methods sterilization. The purpose this study was to compare incidence intraoperative tubal occlusion ligation among obese and nonobese women.This retrospective cohort compared women undergoing interval in operating room between September 2009 December 2011 at single hospital. Serious included: unintended...
INTRODUCTION: The objective of this study was to compare the complication rate hysteroscopic tubal occlusion with interval laparoscopic sterilization among obese and nonobese women. METHODS: We performed a retrospective cohort all women undergoing through ligation or approach (Essure) between September 2009 December 2011 at single large academic medical center. Data collected included sociodemographics, body mass index (BMI), history, surgical time, complications including unintended...
Abstract The current state of policy‐making necessitates clinicians and their organizations to be more engaged. This article provides practical examples how engage in various levels advocacy within pediatric gastroenterology.
Several states have recently enacted laws permanently granting all public school students access to free breakfast and lunch. However, children with dietary restrictions, such as celiac disease (CeD), may encounter barriers participation in these meal programs. We surveyed caregivers of school-aged CeD study universal meals. More than half the did not participate programs due concerns about cafeteria's ability prepare gluten-free (GF) meals safely. Moreover, among those who were food...