- Prostate Cancer Diagnosis and Treatment
- Renal cell carcinoma treatment
- Bladder and Urothelial Cancer Treatments
- Sexual function and dysfunction studies
- Prostate Cancer Treatment and Research
- Urological Disorders and Treatments
- Urinary and Genital Oncology Studies
- Male Reproductive Health Studies
- Hormonal and reproductive studies
- Renal and related cancers
- Urinary Bladder and Prostate Research
- Kidney Stones and Urolithiasis Treatments
- Ureteral procedures and complications
- Sexual Differentiation and Disorders
- Renal and Vascular Pathologies
- Esophageal Cancer Research and Treatment
- Reproductive Health and Technologies
- Urologic and reproductive health conditions
- Genital Health and Disease
- Epigenetics and DNA Methylation
- Cancer Genomics and Diagnostics
- Pediatric Urology and Nephrology Studies
- Statistical Methods in Clinical Trials
- Sexuality, Behavior, and Technology
- Urinary Tract Infections Management
Délégation Paris 6
2016-2023
Clinique Ambroise Paré
2021-2022
Université Paris Cité
2006-2016
Hôpital Bichat-Claude-Bernard
2005-2016
Centre de Neurophysique Physiologie et Pathologie
2016
Assistance Publique – Hôpitaux de Paris
2007-2014
Université Claude Bernard Lyon 1
2006-2013
Délégation Paris 7
2013
Foundation University Islamabad
2012
Service de la Santé Publique
2012
No AccessJournal of UrologyAdult Urology1 May 2013Prediction Cancer Specific Survival After Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma: Development an Optimized Postoperative Nomogram Using Decision Curve Analysis Morgan Rouprêt, Vincent Hupertan, Thomas Seisen, Pierre Colin, Evanguelos Xylinas, David R. Yates, Harun Fajkovic, Yair Lotan, Jay D. Raman, Richard Zigeuner, Mesut Remzi, Christian Bolenz, Giacomo Novara, Wassim Kassouf, Adil Ouzzane, François Rozet, Olivier...
Study Type – Therapy (prospective cohort) Level of Evidence 2b What's known on the subject? and What does study add? Stone density non‐contrast computed tomography (NCCT) is reported to be a prognosis factor for extracorporeal shockwave lithotripsy (ESWL). In this prospective study, we determined that 970 HU threshold stone very specific sensitive beyond which likelihood rendered free poor. Thus, NCCT evaluation before ESWL may useful identify patients should offered alternative treatment...
No AccessJournal of UrologyAdult Urology1 Jan 2009Long-Term Outcomes After Nephron Sparing Surgery for Renal Cell Carcinoma Larger Than 4 cm Matthieu Peycelon, Vincent Hupertan, Eva Comperat, Raphaële Renard-Penna, Christophe Vaessen, Pierre Conort, Marc-Olivier Bitker, Emmanuel Chartier-Kastler, François Richard, and Morgan Rouprêt PeycelonMatthieu Peycelon Department Urology, Groupement Hospitalier Universitaire Est (Pitié-Tenon), Assistance-Publique Hôpitaux de Paris Faculté Médecine et...
Abstract Purpose: The diagnosis of localized prostate cancer is difficult due to a lack cancer-specific biomarkers. Many patients require repeat biopsies diagnose the disease. We investigated whether aberrant promoter hypermethylation in prostatic fluid could reliably detect cancer. Experimental Design: Urine samples were collected after massage from 95 with undergoing radical prostatectomy (63 pT1, 31 pT2, and 1 pT3) 38 control patients. Ten genes (GSTP1, RASSF1a, ECDH1, APC, DAPK, MGMT,...
Owing to the scarcity of upper urinary tract urothelial carcinoma (UUT-UC) it is often necessary for investigators pool data. A patient-specific survival nomogram based on such data needed predict cancer-specific (CSS) post nephroureterectomy (NU). Herein, we propose and validate a CSS NU. Twenty-one French institutions contributed 1120 patients treated with NU UUT-UC. total 667 had full development. Study population was divided into development cohort (397) external validation (270). Cox...
To propose and validate a nomogram to predict cancer-specific survival (CSS) after radical nephroureterectomy (RNU) in patients with pT1-3/N0-x upper tract urothelial carcinoma (UTUC).The international the French national collaborative groups on UTUC pooled data from 3387 treated RNU. Only 2233 chemotherapy naïve were included present study. The population was randomly split into development cohort (1563) external validation (670). build nomogram, logistic regressions used for univariable...
Abstract Promoter hypermethylation of circulating cell DNA has been advocated as a diagnostic marker for prostate cancer, but its prognostic use is currently unclear. To assess this role, we compared from cancer patients with (Group 1, n = 20) and without 2, 22) disease progression age‐matched controls (benign prostatic hyperplasia, Group 3, 22). We measured 10 gene promoters in 2 sequential venous samples, obtained at diagnosis during (median time, 15 months later). Matched time samples...
The thorax is the most frequent extrapelvic location of endometriosis. Thoracic endometriosis probably responsible for high rate recurrent pneumothoraces in females. goal present prospective study was to assess value cancer antigen (CA)125 measurement detection order further enable early and adequate treatment catamenial pneumothorax. Between January 2004 March 2006, 31 females (mean age 32 yrs) underwent pneumothorax surgery. control group comprised 17 males 27 yrs), who videothoracoscopic...
OBJECTIVE To compare the potential of two diagnostic methods for detecting recurrence urothelial cell carcinoma (UCC) bladder, by (i) alterations in microsatellite DNA markers and loss heterozygosity (LOH), (ii) aberrant gene hypermethylation, as UCC has a high rate urinary tract disease can invade muscle if new tumours are overlooked. PATIENTS AND METHODS Over 1 year, urine samples were retrieved from 40 patients already diagnosed with bladder (30 pTa, pTis, eight pT1). Samples collected 6...
Abstract BACKGROUND. The aim of the current study was to establish predictive accuracy Kattan postoperative nomogram for nonmetastatic renal cell carcinoma (RCC) by comparing predictions with actual disease recurrence in patients who underwent surgery a single center France. METHODS. Between 1985 and 2000, 844 were treated RCC. following data collated: age, symptoms, histology, tumor size, grade, TNM 1997 stage, recurrence, progression. For each patient prognostic score (predicted...
Summary Efficacy and safety of l ‐arginine aspartate 8 g combined with 200 mg adenosine monophosphate ( AA ) placebo PL alone for intermittent treatment mild‐to‐moderate erectile dysfunction ED were compared. The study design was a double‐blind, PL‐controlled, two‐way crossover randomized clinical trial 26 patients. assessed by International Index Erectile Function IIEF two additional validated questionnaires [the Erection Hardness Score EHS the Dysfunction Inventory Treatment Satisfaction...
Summary Purines and more specifically adenosine monophosphate (AMP) triphosphate (ATP) have a strong relaxant effect on smooth muscle cells of the dog, rabbit human corpus cavernosum, to approximately same degree as nitric oxide (NO). However, purines are considered modulators erectile function rather than key mediators. This suggests that use combined with NO donors could be effective treat some specific disorders. The relaxation induced by combination l ‐arginine (Arg), natural substrate...
Key Words: shock wave lithotripsy ‹› double J stent ureteral stone lumbar Introduction.We evaluated the effect of presence a on efficacy extracorporeal (ESWL) in treatment stones.Material and methods.Between January 2007 February 2012, we performed retrospective cohort study.Forty-four patients were treated by ESWL for stones included into two groups analysis: group 1, non-stented (n = 27) 2, stented 17).Treatment was abdominal X-ray or CT-scan at 1 month.Stone-free those with residual ≤4 mm...