Jian Cai

ORCID: 0000-0002-2758-2528
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About
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Research Areas
  • Urological Disorders and Treatments
  • Circular RNAs in diseases
  • Genital Health and Disease
  • Urinary and Genital Oncology Studies
  • Cancer-related molecular mechanisms research
  • Bladder and Urothelial Cancer Treatments
  • Sexual function and dysfunction studies
  • Urologic and reproductive health conditions
  • Urinary Bladder and Prostate Research
  • MicroRNA in disease regulation
  • Multiple Myeloma Research and Treatments
  • Prostate Cancer Diagnosis and Treatment
  • Sexual Differentiation and Disorders
  • Patient-Provider Communication in Healthcare
  • Ferroptosis and cancer prognosis
  • Prostate Cancer Treatment and Research
  • Patient Satisfaction in Healthcare
  • Nonmelanoma Skin Cancer Studies
  • Electrospun Nanofibers in Biomedical Applications
  • Neonatal Respiratory Health Research
  • Cleft Lip and Palate Research
  • Hedgehog Signaling Pathway Studies
  • Mesenchymal stem cell research
  • Intraperitoneal and Appendiceal Malignancies
  • Adenosine and Purinergic Signaling

Shenzhen Second People's Hospital
2024

Wenzhou Medical University
2009-2023

First Affiliated Hospital of Wenzhou Medical University
2009-2023

Taixing People's Hospital
2023

Second Hospital of Shandong University
2021-2022

Southern Medical University
2013

Nanfang Hospital
2013

Chinese physicians are not only facing heavy work overloads, but also abuse and injury because of patient mistrust physicians. The primary objective the present study was to measure psychological distress, burnout levels job satisfaction among emergency All from EDs three large general hospitals were recruited undertake a questionnaire-based survey March April 2012. Hospital Anxiety Depression Scale (HADS), Maslach Burnout Inventory-General Survey Minnesota Satisfaction Questionnaire used....

10.1111/1742-6723.12315 article EN Emergency Medicine Australasia 2014-10-15

Circular RNA DDX17 (circDDX17) has been demonstrated as a tumor suppressor in colorectal cancer. However, mechanisms underlying circDDX17 effects cases of prostate cancer (PCa) are not well understood. Thus, herein, we determined measures expression by use the TCGA database. Expression cancer-afflicted tissue samples was qRT-PCR. Functionally, induced remarkable inhibition cell colonizing ability, invasion, and epithelial-mesenchymal transition (EMT) progression vitro. Mechanistically,...

10.1155/2020/1878431 article EN cc-by BioMed Research International 2020-08-21

Bladder cancer (BC), as the most common urinary system tumor type and main cause of tumor-related death, has an unsatisfactory prognosis. In recent years, related literature proposed that cell pyroptosis is inflammatory form programmed death. However, in BC, relationship between expression pyroptosis-related genes prognosis not been elucidated.We got RNA sequencing data from TCGA GEO datasets. Fifty-two were extracted for further explore. Then, we compared gene levels normal bladder BC...

10.2147/ijgm.s337735 article EN cc-by-nc International Journal of General Medicine 2021-11-01

to describe the methodology of transurethral seminal vesiculoscopy and anatomy area verumontanum, determine safety this procedure, especially in terms postoperative complications.This retrospective observational study enrolled 144 patients with intractable hematospermia from May 2011 August 2019. A 4.5/6.5-Fr vesiculoscope was inserted into vesicle deal positive findings. The solution quinolones used rinse each vesicle.In study, Transurethral successfully performed 139 (96.53%)....

10.1186/s12894-021-00817-4 article EN cc-by BMC Urology 2021-03-27

Chronic obstructive pulmonary disease (COPD) as an inflammatory respiratory system is caused by exposure to cigarette smoke and tobacco in long-term. Some anti-inflammatory peptides can control inflammation COPD. N-acetyl-seryl-aspartyl-proline (Ac-SDKP) vasoactive intestinal peptide (VIP) have effect, and, this study, the effect of Ac-SDKP VIP on COPD was studied. After producing smoke-induced mice model, which were treated with Ac-SDKP, levels antioxidant-related factors (malondialdehyde...

10.1111/fcp.12811 article EN Fundamental and Clinical Pharmacology 2022-06-28

To examine the association between age at diagnosis and cancer-specific mortality (CSM) in primary urachal adenocarcinoma.The data was obtained from National Cancer Institute's Surveillance, Epidemiology, End Results program (SEER). A total of 393 patients were included study. Smooth curve fitting two-piecewise Cox proportional hazards models used to identify nonlinearity initial survival rate. Survival time different groups compared using Kaplan-Meier curves log-rank test.Using smooth we...

10.21037/tau-19-863 article EN Translational Andrology and Urology 2020-06-01

Background and Aims: There is a lack of research on metastatic renal pelvis cell carcinoma in the current literature. In this study, we aimed to detect distant patterns carcinoma, illustrated affection different sites, surgery primary site chemotherapy prognosis outcomes patients with diverse conditions. Methods: We collected data between 2010 2015 from Surveillance, Epidemiology End Results database. Kaplan–Meier analysis log-rank test was used for survival comparisons. Multivariate Cox...

10.1177/15330338211004914 article EN cc-by-nc Technology in Cancer Research & Treatment 2021-01-01

Burn is one of the common traumatic diseases in clinics. After deep burn, complicated changes condition are caused by burn wound, which ends with repair wound. For patients burns, whether wound can be repaired as soon possible key to success clinical treatment. due lack an autologous skin source, scar hyperplasia at donor site, graft postoperative flap necrosis, and other problems traditional surgical procedures, method improving function only source has been unable perform later...

10.1155/2021/6963401 article EN Evidence-based Complementary and Alternative Medicine 2021-10-26

<title>Abstract</title> <bold>Background: </bold>Heart failure (HF) is the leading cause of death in patients with maintenance hemodialysis (MHD). Biomarkers has an important guiding role early diagnosis, risk stratification, and prognostic assessment HF. Increasing studies have indicated that long non-coding RNAs (lncRNAs) played indispensable regulatory network This study was aiming to explore expression profiles lncRNAs treated MHD developing heart failure. <bold>Methods:...

10.21203/rs.3.rs-4549448/v1 preprint EN Research Square (Research Square) 2024-07-02

Heart failure (HF) is the leading cause of death in patients with maintenance hemodialysis (MHD). Biomarkers has an important guiding role early diagnosis, risk stratification, and prognostic assessment HF. Increasing studies have indicated that long non-coding RNAs (lncRNAs) played indispensable regulatory network This study was aiming to explore expression profiles lncRNAs treated MHD developing heart failure. Peripheral blood mononuclear cells were isolated from 4 reduced ejection...

10.1038/s41598-024-81080-z article EN cc-by-nc-nd Scientific Reports 2024-11-28

To develop a nomogram for predicting cancer-specific survival (CSS) of patients with non-metastatic primary adenocarcinoma the bladder (NMACB).We used retrospective cohort study design. Patient data were obtained from SEER database, univariate and multivariate Cox regression analyses performed to identify factors associated CSS. A visualization model was established using R language software predict rate. Harrell's concordance index (C-index), area under receiver operating characteristic...

10.21037/tcr-20-354 article EN Translational Cancer Research 2020-09-01

To develop a nomogram to predict cancer-specific survival (CSS) in patients with metastatic testicular germ cell tumors (mTGCTs).Data were obtained from the Surveillance, Epidemiology, and End Results database. Univariate multivariate Cox regression models used identify factors associated CSS. Survival times between different groups compared using Kaplan-Meier curves log-rank test. A visualization model was established R language rates. Harrell's concordance index (C-index), area under...

10.21037/tcr.2020.03.59 article EN Translational Cancer Research 2020-04-01

Abstract Purpose: to describe the methodology of transurethral seminal vesiculoscopy and anatomy area verumontanum, determine safety this procedure, especially in terms postoperative complications. Methods: This retrospective observational study enrolled 144 patients with intractable hematospermia from May 2011 August 2019. A 4.5/6.5-Fr vesiculoscope was inserted into vesicle deal positive findings. The solution quinolones used rinse each vesicle. Results: In study, Transurethral...

10.21203/rs.3.rs-213943/v1 preprint EN cc-by Research Square (Research Square) 2021-02-22

Objective To evaluate the application of mind map on patients with urinary continence after benign prostate hyperplasia (BPH) surgery and provide clinical evidence for improving quality postoperative nursing. Methods From February 2013 to April 2014, we selected 160 cases who suffered BPH, divided into experimental group control average by method random number table. The received routine nursing while built up utilized it take care patients. Patients in two groups had been observed...

10.3760/cma.j.issn.1674-2907.2015.02.013 article EN Zhonghua xiandai huli zazhi 2015-01-16

Purpose: Capsule endoscopy (CE) and double-balloon enteroscopy (DBE) have been reported to provide comparable diagnostic yields in patients with obscure gastrointestinal bleeding (OGIB). In addition, CE has recommended as a first-line tool for investigation of OGIB. However, few studies directly compared the two modalities acute overt-OGIB. This study was compare yield direct DBE overt-OGIB evaluate outcomes short-term follow-up. Methods: Prospective conducted between June 2012 December...

10.14309/00000434-201310001-01891 article EN The American Journal of Gastroenterology 2013-10-01

Objective To study the relationship between chromosomal abnormality and Y chromosome microdeletions male infertility. Methods Lymphocytes were cultured from peripheral blood of 1975 infertility patients stained with Giemsa. The chromosomes analyzed under microscope. specific sequence tags (STS) selected, then in AZF regions screened by polymerase chain reaction (PCR) azoospermia oligozoospermia patients. Results There 305 cases detected abnormalities (15.44%) cases. 101 (5.11 %) autosome...

10.3760/cma.j.issn.1000-6702.2011.03.005 article EN Zhonghua miniao waike zazhi 2011-03-15
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