A5067612720- SARS-CoV-2 and COVID-19 Research
- Viral gastroenteritis research and epidemiology
- Animal Virus Infections Studies
- Viral Infections and Outbreaks Research
- SARS-CoV-2 detection and testing
- Respiratory viral infections research
- COVID-19 diagnosis using AI
- COVID-19 Clinical Research Studies
- Influenza Virus Research Studies
- COVID-19 epidemiological studies
- Herpesvirus Infections and Treatments
- Animal Disease Management and Epidemiology
- Virology and Viral Diseases
- Mosquito-borne diseases and control
- Hepatitis Viruses Studies and Epidemiology
- Bacteriophages and microbial interactions
- Veterinary medicine and infectious diseases
- Viral Infections and Vectors
- Rabies epidemiology and control
- Infectious Encephalopathies and Encephalitis
Kwame Nkrumah University of Science and Technology
2019-2024
Kumasi Centre for Collaborative Research in Tropical Medicine
2019-2024
Charité - Universitätsmedizin Berlin
2020
Kwame Nkrumah University
2020
University of Science and Technology
2020
Abstract Background Rabies, caused by a lyssavirus, is viral zoonosis that affects people in many parts of the world, especially those low income countries. Contact with domestic animals, dogs, main source human infections. Humans may present disease only after long period exposure. Nearly half rabies cases occur children <15 years old. We report on fatal case Ghanaian school child 5 exposure incident, and vital role molecular tools confirmation diagnosis. Case presentation The patient,...
Background Global cases of COVID-19 continue to rise, causing havoc several economies. So far, Ghana has recorded 48,643 confirmed with 320 associated deaths. Although summaries data are usually provided by the Ministry Health, detailed epidemiological profile limited. This study sought describe socio-demographic features, pattern spread and viral load dynamics among subjects residing in northern, middle part southern belt Ghana. Methods was a cross-sectional retrospective that reviewed...
Since late 2019, the coronavirus disease 2019 (COVID-19) outbreak, caused by SARS-CoV-2, has rapidly evolved to become a global pandemic. Each country was affected but with varying number of infected cases and mortality rates. Africa hit pandemic rose sharply. In this study, we investigated 224 SARS-CoV-2 genome sequences from Global Initiative on Sharing Avian Influenza Data (GISAID) in early part which 69 were Africa. We analyzed total 550 mutations comparing them reference sequence Wuhan....
Background The declaration of COVID-19 as a pandemic on March 11 2020, by the World Health Organisation prompted need for sustained and rapid international response. In swift response, Government Ghana, in partnership with Zipline company, launched use Unmanned Automated Vehicles (UAV) to transport suspected samples from selected districts two foremost testing centres country. Here, we present experiences employing this technology its impact time second largest centre, Kumasi Centre...
Abstract Background Apart from the huge worldwide economic losses often occasioned by bovine coronavirus (BCoV) to livestock industry, particularly with respect cattle rearing, continuous surveillance of virus in and small ruminants is essential monitoring variations that could enhance host switching. In this study, we collected rectal swabs a total 1,498 cattle, sheep goats. BCoV detection was based on reverse transcriptase polymerase chain reaction. Sanger sequencing partial RNA-dependent...
Known human coronaviruses are believed to have originated in animals and made use of intermediate hosts for transmission humans. The most the known, but not HCoV-NL63. This study aims assess possible role some major domestic livestock species as We developed a testing algorithm high throughput screening sera with ELISA confirmation recombinant immunofluorescence assay antibodies against HCoV-NL63 livestock. Optimization showed capability significantly distinguish from HCoV-229E (U = 27.50, p...
The novel coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), continues to remain a global challenge. There is emerging evidence of SARS-CoV-2 virus found in the blood patients from China and some developed countries. However, there inadequate data reported Ghana other parts Africa, where transfusion service heavily relies on voluntary replacement donors. This study aimed investigate whether plasma infected individuals could pose...
The emergence of Middle East Respiratory Syndrome Coronavirus (MERS-CoV), nearly a decade ago with worldwide distribution, was believed to be zoonotic origin from bats dromedary camels as intermediate hosts. There is likelihood other domestic livestock serving hosts for this virus. presence coronaviruses, closely related MERS-CoV in Ghanaian bats, presented the opportunity test hypothesis transmissibility virus through species. possible interactions between and 31 household farms were...
Abstract Respiratory viral infections are important causes of morbidity and mortality worldwide. Information on circulating respiratory viruses among prisoners is lacking, although this public health importance knowledge would assist in putting place preventive measures to forestall disease outbreaks. The aim study therefore was get the footprint such diseases that have epidemic potential be described quantified for control. Prisoners remand numbering 203 a prison Kumasi, Ashanti Regional...
Across the globe, outbreak of COVID-19 pandemic is causing distress with governments doing everything in their power to contain spread novel coronavirus (SARS-CoV-2) prevent morbidity and mortality. Actions are being implemented keep health care systems from overstretched curb outbreak. Any policy responses aimed at slowing down virus mitigating its immediate effects on require a firm basis information about absolute number currently infected people, growth rates, locations/hotspots...
Abstract Background Encephalitis is a serious disease of the brain characterized by prodromal and specific neurological symptoms. HIV infections offer opportunistic viruses, such as Varicella-zoster virus (VZV), chance to cause encephalitis in patients. There lack information on genetic diversity VZV Ghana other parts Africa which requires sequencing characterization studies address. The active evolution HIV-1 West also continuous surveillance for emergence new forms. Case presentation was...
Viral encephalitis is a rare, yet severe neurological disorder. It poses significant public health threat due to its high morbidity and mortality. Despite the disproportionate burden of disease in impoverished African countries, true extent problem remains elusive scarcity accurate diagnostic methods. The absence timely effective tools, particularly Real-time Polymerase Chain Reaction, has led misguided treatment, an underestimation Ghana. We conducted prospective cross-sectional study...
Abstract Background Hepatitis E virus (HEV) is among the leading causes of viral hepatitis in most developing countries. Zoonotic acquisition HEV genotype 3 from swine has come into focus more recently. Available studies on Ghana and other countries region do not provide enough information towards understanding epidemiology human animal populations. Towards this end, we conducted a comparative cross-sectional study to determine seroprevalence risk factors associated with exposure, both...
Abstract Background : Apart from the huge worldwide economic losses often occasioned by bovine coronavirus (BCoV) to livestock industry particularly cattle, continuous surveillance of virus in cattle and small ruminants is essential monitoring variations that could enhance host switching. In this study, we collected rectal swabs a total 1,498 sheep goats. BCoV detection was based on reverse transcriptase polymerase chain reaction. Sanger sequencing partial RNA-dependent RNA (RdRp) region for...
In regions lacking genomic data, analysis of sequences from the early stages an outbreak can provide important insights into diversity pathogens present. Following detection first imported case COVID-19 in Northern sector Ghana on 13th March 2020, we have now molecularly characterized and phylogenetically analysed including three (3) complete genomes severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) isolated nine (9) patients observed Ghana. Eight (8) these reported with a recent...
Abstract Background : Apart from the huge worldwide economic losses often occasioned by bovine coronavirus (BCoV) to livestock industry particularly cattle, continuous surveillance of virus in cattle and small ruminants is essential monitoring variations that could enhance host switching. In this study, we collected rectal swabs a total 1,498 sheep goats. BCoV detection was based on reverse transcriptase polymerase chain reaction. Sanger sequencing partial RNA-dependent RNA (RdRp) region for...
Abstract Background: Influenza viruses are known to be responsible for a number of respiratory disease outbreaks worldwide. While there exists documented information on influenza which allows effective strategic preparedness activities in industrialized countries, the same cannot said developing and underdeveloped countries. It therefore behoves countries document circulating strains influenza. Such will enable prioritization prevention more targeted strategies. In this paper, we report...
Abstract Background : Apart from the huge worldwide economic losses often occasioned by bovine coronavirus (BCoV) to livestock industry particularly cattle, continuous surveillance of virus in cattle and small ruminants is essential monitoring variations that could enhance host switching. In this study, we collected rectal swabs a total 1,498 sheep goats. BCoV detection was based on reverse transcriptase polymerase chain reaction. Sanger sequencing partial RNA-dependent RNA (RdRp) region for...
Abstract Background Influenza viruses are known to be responsible for a number of respiratory disease outbreaks worldwide. While there exists documented information on influenza which allows effective strategic preparedness activities in industrialized countries, the same cannot said developing and underdeveloped countries. It therefore behoves countries document circulating strains influenza. Such will enable prioritization prevention more targeted strategies. In this paper, we report three...
Abstract Background: Influenza viruses are known to be responsible for a number of respiratory disease outbreaks worldwide. While there exists documented information on influenza which allows effective strategic preparedness activities in industrialized countries, the same cannot said developing and underdeveloped countries. It therefore behoves countries document circulating strains influenza. Such will enable prioritization prevention more targeted strategies. In this paper, we report...
Abstract Background: Apart from the huge worldwide economic losses often occasioned by bovine coronavirus (BCoV) to livestock industry particularly cattle, continuous surveillance of virus in cattle and small ruminants is essential monitoring variations that could enhance host switching. Methods: In this study, we collected rectal swabs a total 1,498 sheep goats. BCoV detection was based on reverse transcriptase polymerase chain reaction. Sanger sequencing partial RNA-dependent RNA (RdRp)...
Abstract Background : Apart from the huge worldwide economic losses often occasioned by bovine coronavirus (BCoV) to livestock industry particularly cattle, continuous surveillance of virus in cattle and small ruminants is essential monitoring variations that could enhance host switching. In this study, we collected rectal swabs a total 1,498 sheep goats. BCoV detection was based on reverse transcriptase polymerase chain reaction. Sanger sequencing partial RNA-dependent RNA (RdRp) region for...