A5103057055- Head and Neck Cancer Studies
- Head and Neck Surgical Oncology
- Ferroptosis and cancer prognosis
- Lung Cancer Research Studies
- Cancer, Lipids, and Metabolism
- Multiple and Secondary Primary Cancers
- Breast Cancer Treatment Studies
- Colorectal and Anal Carcinomas
- Cholangiocarcinoma and Gallbladder Cancer Studies
- RNA modifications and cancer
- Global Cancer Incidence and Screening
- Polyomavirus and related diseases
- Salivary Gland Tumors Diagnosis and Treatment
- Endometrial and Cervical Cancer Treatments
- Cervical Cancer and HPV Research
ShenZhen People’s Hospital
2024-2025
Sun Yat-sen University
2021-2022
The First Affiliated Hospital, Sun Yat-sen University
2021-2022
Chinese University of Hong Kong
2016
University of Hong Kong
2016
Background A second primary malignant tumor is one of the most important factors affecting long-term survival young women with breast cancer (YWBC). As main treatments for YWBC patients, postoperative radiotherapy (PORT) may increase risk malignancy (SPM). Methods Machine learning components, including ridge regression, XGBoost, k-nearest neighbor, light gradient boosting machine, logistic support vector neural network, and random forest, were used to construct a predictive model identify...
BackgroundInduction chemotherapy regimens of docetaxel and cisplatin plus fluorouracil (TPF) are currently clinically used for patients with locoregionally advanced nasopharyngeal carcinoma (LA-NPC) but have well-known side effects, such as myelosuppression diarrhea. A (TP) regimen was developed to decrease the toxic effects induced by fluorouracil. In this trial, we assessed whether TP induction noninferior TPF regimen.MethodsWe performed an open-label, noninferiority, phase 3, multicentre,...
Background Oncoprotein-Induced Transcript 3 Protein (OIT3) was identified as a liver-specific gene with abnormal expression in hepatocellular carcinoma (HCC). Herein, we aimed to examine the function and specific mechanism of OIT3 HCC. Methods Bioinformatic analyses tissue microarray via immunohistochemistry were used validate The biofunctions HCC determined vitro vivo . confirmed by RNA-Sequence Western blotting. uni- multivariate identify independent predictors for Results Low observed...
In this trial, we aimed to assess the efficacy and safety of radiotherapy with nedaplatin or cisplatin in patients locally advanced cervical cancer.We conducted an open-label, non-inferiority, phase III, randomized, controlled trial. Eligible stage IIB-IVA carcinoma were randomly assigned receive either for two cycles concurrently radiotherapy. We reported therapy-associated harms survival. The study was registered chictr.org.cn, number ChiCTR1800020527.We 68 nedaplatin-based cisplatin-based...
Objective: This study aims to compare the treatment outcomes of concurrent chemoradiotherapy (CCRT) versus radiotherapy (RT) alone in stage II nasopharyngeal carcinoma (NPC) patients. Methods: We retrospectively collected 601 NPC patients treated two hospitals between June 2003 2016. All were divided into CCRT group ( n = 255) and RT 346). Overall survival (OS), locoregional failure-free (LRFFS), progression-free (PFS), distant metastasis-free (DMFS) assessed using Kaplan-Meier method. The...
Background: Second primary malignant tumor is one of the most important factors affecting long-term survival young women with breast cancer (YWBC) cases. As main treatments for YWBC cases, postoperative radiotherapy (PORT) may increase risk second malignancy (SPM). We aim to identify SPMs in cases.Methods: Machine learning components, including ridge regression, XGBoost, k-nearest neighbor, light gradient boosting machine, logistic support vector neural network, random forest, were used...
Abstract Objectives To explore the efficacy of induction chemotherapy (IC) plus concurrent chemoradiotherapy (CCRT) in stage II nasopharyngeal carcinoma (NPC) treated with intensity‐modulated radiotherapy (IMRT). Methods Totally, 450 eligible patients staged NPC on basis 8th edition AJCC/UICC TNM staging system were eventually included from January 2010 to September 2020. The one‐to‐one propensity score‐matched (1:1 PSM) analysis was employed balance variables. We conducted univariate and...