A5066880347- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Advanced Radiotherapy Techniques
- Medical Imaging and Pathology Studies
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Radiomics and Machine Learning in Medical Imaging
- Radiopharmaceutical Chemistry and Applications
- Lung Cancer Treatments and Mutations
- Medical Imaging Techniques and Applications
- Bladder and Urothelial Cancer Treatments
- Radiation Dose and Imaging
- Cancer, Hypoxia, and Metabolism
- Cancer Genomics and Diagnostics
- Multiple and Secondary Primary Cancers
- Foucault, Power, and Ethics
- Breast Cancer Treatment Studies
- Corporate Management and Leadership
- Ethics in Clinical Research
- Health and Conflict Studies
- Cystic Fibrosis Research Advances
- Ferroptosis and cancer prognosis
- Biochemical effects in animals
- Urologic and reproductive health conditions
Paracelsus Medical University
2015-2025
University of Salzburg
2015-2024
Salzburger Landeskliniken
2019-2022
Paracelsus Medizinische Privatuniversität
2020
University of Nebraska Medical Center
1995
Rectal spacers are used to limit dose the anterior rectal wall in high external beam radiation therapy of prostate and have been shown reduce induced toxicity. Here we report complication rate toxicity implantation procedure a large cohort patients who either received gel- or balloon-type spacer.In total, 403 spacing, 264 with balloon, 139 gel. Allocation was non-randomized. Two hundred seventy-six were treated normofractionated regimen, remaining 125 moderate hypofractionation. Spacer...
For years physicians have observed a high incidence of upper respiratory tract infections (URTI) after strenuous exercise. Mucosal surfaces represent first-line-of-defense against infections, and pollutants or organisms entrapped in secretions are cleared by mucociliary transport. Little is known about this mechanism during The purpose study was to examine the nasal clearance (NMCC) amateur runners competing marathon race. Twelve entered an inner-city race 10 healthy sedentary subjects...
Abstract Background Chemoradiotherapy (CRT) is the standard treatment for patients with inoperable stage III non‐small cell lung cancer (NSCLC) III. With a median OS beyond 30 months, adequate pulmonary function (PF) essential to ensure acceptable quality of life after treatment. Forced expiratory volume in 1 second (FEV1) and diffusing capacity carbon monoxide (DLCO) are most widely used parameters assess function. The aim current study was evaluate dose‐volume effects accelerated high‐dose...
Abstract For prostate cancer, the role of elective nodal irradiation (ENI) for cN0 or pN0 patients has been under discussion years. Considering recent publications randomized controlled trials, cancer expert panel German Society Radiation Oncology (DEGRO) aimed to discuss and summarize current literature. Modern trials have recently published both treatment-naïve (POP-RT trial) after surgery (SPPORT trial). Although there are more reliable data date, we identified several limitations...
To date, patients with glioblastoma still have a bad median overall survival rate despite radiation dose-escalation and combined modality treatment. Neurocognitive decline is crucial adverse event which may be linked to high doses the cortex. In planning study, we investigated impact of dose constraints cerebral cortex its relation organs at risk for patients. Cortical sparing was implemented into optimization process two approaches: classical intensity-modulated radiotherapy (IMRT) robust...
Gold-marker-based image-guided radiation therapy (IGRT) of the prostate allows to correct for inter- and intrafraction motion therefore safely reduce margins planning target volume (PTV). However, pelvic PTVs, when coadministered in a single plan (registered gold markers [GM]), require reassessment margin concept since movement is independent from bony anatomy which lymphatics are usually referenced to.We have revisited translational relative obtain adequate PTVs compensating mismatch...
Abstract Purpose In ultrahypofractionated radiation concepts, managing of intrafractional motion is mandatory because tighter margins are used and random errors resulting from prostate movement not averaged out over a large number fractions. Noninvasive live monitoring desirable asset for LINAC-based stereotactic body therapy (SBRT). Methods We prospectively analyzed novel tracking device (RayPilot HypoCath™; Micropos Medical AB, Gothenburg, Sweden) where transmitter noninvasively positioned...
Prostate cancer (PCA) is highly heterogeneous in terms of its oncologic outcome. We therefore aimed to tailor radiation treatment the risk status by using three different hypofractionated regimen differing applied dose, use rectum spacer, inclusion pelvic lymph nodes (pLN) and androgen deprivation therapy (ADT). Here we report on acute toxicity, quality life (QOL) outcome at a median follow-up 12 months.A total 221 consecutive PCA patients received intensity-modulated radiotherapy (IMRT)....
Recently, polyclonal unspecific human immunoglobulin was suggested as a new agent for the localization of inflammatory lesions. Little information about biodistribution this radiopharmaceutical reported so far. To obtain further information, 99mTc-labelled (HIG) administered to volunteer with presumed normal biokinetics. The absorbed doses organs were calculated according MIRD concept. scintigraphic images at 1, 2, 4 and 24 h post injection demonstrated prolonged activity retention in blood...
The risk of venous thromboembolism (VTE) and arterial thrombosis events (ATE) potential corresponding factors were assessed in patients with cancer diagnosed COVID-19. Adults treated community health systems who COVID-19 2020 evaluated for absolute (risk) ATE VTE. Thrombotic ascertained the 90-day window starting diagnosis (index). ICD codes defined baseline comorbidities, COVID-19, thrombotic events. 7591 included median age 67, 6 % cardiovascular disease (CVD), 4 prior VTE, 24 hospitalized...
Various randomized phase III clinical trials have compared moderately hypofractionated to normofractionated radiotherapy (RT). These modalities showed similar effectiveness without major differences in toxicity. This project was conducted by the Prostate Cancer Expert Panel of German Society Radiation Oncology (DEGRO) and Working Party on Society. We aimed investigate expert opinions use RT as a definitive treatment for localized prostate cancer German-speaking countries.A 25-item, web-based...
Abstract A significant number of prostate cancer patients are long-term survivors after primary definitive therapy, and the occurrence late side effects, such as second cancers, has gained interest. The aim this editorial is to discuss most current evidence on cancers based six retrospective studies published in 2021–2024 using large data repositories not accounting for all possible confounding factors, smoking or pre-existing comorbidities. Overall, treated with curative radiotherapy have...
Drug Prescribing for Patients with Chronic Kidney Disease in General Practice: a Cross-Sectional Study
Zusammenfassung Die Ergebnisse betreffen 48 Untersuchungen bei Verdacht auf Phäochromozytom oder Neuroblastom, die zwischen 1982 und 1984 in Erlangen mit 131J-meta-Benzylguanidin durchgeführt wurden. MIBG-Szintigraphie erwies sich als hochspezifisch. Falsch positive Befunde können vermieden werden, wenn schwachen Anreicherungen genaue Entsprechung zu den Ergebnissen morphologischer (CT, Sonographie) gesucht durch Verlaufsbeobachtungen sichergestellt wird, daß es nicht um Gallenwegs-, Darm-...