Abstract Objective: To compare the efficacy of fractional CO2 laser therapy with topical estrogen for treatment postmenopausal genitourinary syndrome menopause. Methods: We conducted a randomized controlled clinical trial involving 25 women. Participants were aged between 50 and 65 years at least 1 year amenorrhea follicle-stimulating hormone levels >40 IU/L. The women into two groups: group ( n = 13) vaginal 12). Changes in epithelium thickness, Frost index, cell maturation analyzed both...

Identifying factors, including human papillomavirus (HPV) genotypes, associated with abnormal anal cytology in HIV-infected women have implications for squamous cell cancer (SCC) prevention women. Anal and cervical samples were collected cytology, tested high-(HR-HPV) low-risk HPV (LR-HPV) genotypes a cross-sectional analysis of the IPEC Women's HIV Cohort (Rio de Janeiro, Brazil). Multivariate log-binomial regression models estimated prevalence ratios factors [≥atypical cells undetermined...

Hamartomas were first described by Albrecht in 1904, who defined them as tumor-like malformations which there was abnormal blending of the normal components an organ. The myoid hamartoma is a rare benign lesion breast and has uncertain origin, possibly walls blood vessels, muscularis mammillae areolae, mainly myoepithelium. We report 3 cases hamartomas breast, with clinical, radiologic, histopathological findings, review literature. lesions showed ducts lobules, entrapped muscular stroma...

<b><i>Objective:</i></b> Our objective was to verify the sensitivity and specificity of dual immunocytochemistry staining for p16 Ki-67 in liquid-based samples (the “dual” assay) cervical lesion screening, compared biopsy findings human papillomavirus (HPV) DNA molecular detection. <b><i>Study Design:</i></b> Sensitivity, specificity, positive (PPV) negative (NPV) predictive values “dual assay” were calculated histopathological results...

In this pilot, prospective, randomized, double-blind study, the authors compared efficacy of oxytocin with promestriene in improving vaginal atrophy Genitourinary Syndrome Menopause (GSM). A total 51 postmenopausal women symptoms GSM were evaluated. They randomized into two groups: (25 patients) and (26 evaluated before after 90 days treatment; evaluation was based on domains Female Sexual Function Index (FSFI) (lubrication, satisfaction, pain during sexual intercourse), clinical visual...

To evaluate cyclin-dependent kinase inhibitor 2A (CDKN2A) and cytokeratin 7 (CK7) expression in cervical intraepithelial neoplasia (CIN) formalin-fixed samples.Staining with antibody clones G175-405 for CDKN2A OV-TL 12/30 CK7 were evaluated the detection of protein expressions compared 147 patients CIN.Clinical follow-up CIN1 CIN2 showed that most had a favorable outcome. Single or their combined greater sensitivity negative predictive value CIN1, corresponding to non-development disease....

To compare the efficacy of CO2 fractional laser with that topical estriol for treating genitourinary syndrome menopause and to investigate relationship between epithelial thickness vaginal atrophy.Twenty-five menopausal women were randomized receive either or estrogen treatment. Vaginal biopsies before after treatment compared assess amount distribution progesterone receptors.Estrogen receptor levels statistically similar groups Although there was no change over time in group, an increase...

OBJETIVOS: avaliou-se o tecido mamário de mulheres antes e depois seis meses terapia estroprogestativa combinada contínua (0,625 mg estrogênios conjugados eqüinos associados a 2,5 acetato medroxiprogesterona). MÉTODOS: todas as pacientes foram avaliadas se instituir tratamento consideradas aptas para este. Foram obtidos fragmentos por meio biópsia percutânea com agulha grossa (acoplada um propulsor automático - "core-biópsia"). O material foi fixado os cortes corados hematoxilina-eosina....

PURPOSE: To evaluate the relationship between microvascular density and expression of vascular endothelial growth factor (VEGF) KIT as possible markers angiogenic stimulus in astrocytic tumors correlate it with histopathological grading. METHODS: We enrolled 99 surgical specimens supratentorial for analysis VEGF subsequent correlation MVD RESULTS: correlated (p<0.005) both grading (p<0.005). had no significant (p=0.657). CONCLUSION: constitute important pathways angiogenesis astrocytomas...

Background: It is scarce in the literature studies regarding treatment and objective analysis of survival chances burned patients. Some investigations indicates need for obtaining specific data to population studied characteristics such as social condition nutritional status are suggested be relevant patient’s evolution. We aimed describe mortality a Treatment Center Burn Unit (BU) Brazil. Methods: analyzed 76 victims hospitalized with fatal outcome General Hospital São Matheus 10 years...

Zusammenfassung Der Wert einer präoperativen gerinnungsanalytischen Screening-Untersuchung zur Erhöhung der Patientensicherheit wird kontrovers diskutiert. In prospektiven Beobachtungsstudie mit dem Endpunkt Blutungskomplikation wurde bei 638 Patienten aus elektiven Viszeralchirurgie die Bedeutung Bestimmung von Quick-Wert, APTT und Thrombozytenzahl untersucht. Zusätzlich allen eine standardisierte Anamnese bezüglich möglichen Hämostasestörung erhoben. Postoperative Blutungskomplikationen...

Hemangiopericytomas are rare tumors arising from the proliferation of pericytes.They may be found in lungs, bones, skull, deep soft tissue or limbs.The tumor has an unpredictable prognosis and when it affects orbital region, have aggressive behavior, with high incidence recurrence.We report a case hemangiopericytoma highlight clinical, surgical, histopathological features these tumors.Orbital hemangiopericytomas usually solid, slow-growing tumors.They should considered differential diagnosis...

Introduction: Diagnostic reproducibility and determination of prognostic factors in cervical intraepithelial neoplasias grades 1 2 are still relevant problems the daily practice gynecological histopathology.Objective: To correlate value morphological reclassification p16 immunoexpression with clinical outcome.Materials methods: Sixty-six patients were included (34 neoplasia grade 1, 32 2); an immunohistochemical study according to Lower Anogenital Squamous Terminology (LAST) Consensus by...

RRH: Rural and Remote Health. Published article number: 7126 - <i>Chlamydia trachomatis</i>, <i>Neisseria gonorrhoeae</i> human papillomavirus infections of lower genital tract Indigenous women from Xingu Park

O fibroistiocitoma maligno variante angiomatóide constitui entidade rara e geradora de controvérsia, especialmente quanto a sua histogênese. Apresenta como peculiaridades o acometimento preferencial da faixa etária pediátrica comportamento biológico indolente, tendo baixas taxas metastatização. No presente caso, paciente feminina 6 anos apresentou, em decorrência lesão extremidade inferior, metástase linfonodal inguinal.

Problemstellung: Seit Mai 2003 führen wir im Knappschaftskrankenhaus Bottrop die HDR-Afterloading Therapie beim Prostatacarcinom durch. Als Kombinationsprotokoll mit zusätzlichen 3D konformalen Strahlentherapie.