Xuefang Gu

ORCID: 0000-0002-2851-3700
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About
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Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Electrochemical sensors and biosensors
  • Biosensors and Analytical Detection
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Advanced Nanomaterials in Catalysis
  • Electrochemical Analysis and Applications
  • Molecular Junctions and Nanostructures
  • Nanocluster Synthesis and Applications
  • Conducting polymers and applications
  • Adipose Tissue and Metabolism
  • Magnetism in coordination complexes
  • Crystallography and molecular interactions
  • Pharmacological Effects and Assays
  • Diet, Metabolism, and Disease
  • Liver Disease Diagnosis and Treatment
  • Muscle Physiology and Disorders
  • Electrocatalysts for Energy Conversion
  • Pancreatic and Hepatic Oncology Research
  • Antifungal resistance and susceptibility
  • Advanced Computing and Algorithms
  • Nanomaterials for catalytic reactions
  • Analytical Chemistry and Sensors
  • Advanced Biosensing Techniques and Applications

Nantong University
2014-2024

Soochow University
2013-2024

Second Affiliated Hospital of Soochow University
2021-2024

Xian Yang Central Hospital
2021

The Scarborough Hospital
2017-2021

University of Toronto
2017-2021

Hebei General Hospital
2020

Nantong Science and Technology Bureau
2015-2019

Trace detection of polycyclic aromatic hydrocarbons (PAHs) by surface-enhanced Raman scattering (SERS) on a metal sandwich substrate bridged 1,10-decanedithiolis is reported in this work. The bowl-shaped silver cavity (BSSC) thin film bottom layer was prepared electrodeposition using closely packed monolayer 500 nm diameter polystyrene spheres as template. as-prepared array has proven to be SERS-active with excellent performance and reproducibility when p-aminothiophenol (PATP) the probe...

10.1039/c3ra43442g article EN RSC Advances 2013-01-01

A mercapto-terminated trinuclear Ni(<sc>ii</sc>) complex was synthesized and used as an electrocatalyst for the detection of hydrazine hydrate.

10.1039/c5ra23809a article EN RSC Advances 2015-12-28

In this study, a metal sandwich substrate bridged by an immunocomplex has been created for surface enhanced Raman scattering (SERS)-based immunoassay. The bottom bowl-shaped silver cavity thin film layer was prepared electrodeposition using closely packed monolayer of 700 nm diameter polystyrene spheres as template. reflection spectra the films were recorded function thickness, and then correlated with SERS enhancement p-aminothiophenol probe molecule. results demonstrate that can be...

10.1039/c3an36792d article EN The Analyst 2013-01-01

A one-pot route to the synthesis of Au/Ag bimetallic nanoparticles with a high SERS activity for detection proteins at low concentration.

10.1039/c9nj02879j article EN New Journal of Chemistry 2019-01-01

Non-alcoholic fatty liver disease (NAFLD) is one of the primary causes chronic and closely linked to insulin resistance, type 2 diabetes mellitus (T2DM), dyslipidemia. However, no effective drug therapies have been approved treat this disease. The present research aimed evaluate therapeutic effects combination oral hypoglycemic metformin (MET) a natural product malvidin (MAL) on hepatic damage in HFD/STZ-induced diabetic rats.Sprague-Dawley rats were divided into five groups: normal control...

10.2147/dddt.s307257 article EN Drug Design Development and Therapy 2021-06-01

Two 2-D microporous metal–organic frameworks, [Zn(BDC)(MbIm)]·2DMF (1) and [Cd3(BDC)3(MbIm)2(DMF)2]·2DMF (2), have been synthesized by solvothermal reaction of 1,4-benzenecarboxylic acid (H2BDC) 2-methylbenzimidazole (MbIm) with zinc/cadmium nitrate. Single-crystal X-ray diffraction analysis indicates that 1 consists the well-known zinc paddle-wheel motif which is linked bridging dicarboxylates to form square grids. The layers stack offset due effect spatial structure MbIm ligand...

10.1080/00958972.2016.1172070 article EN Journal of Coordination Chemistry 2016-03-29

There are rare reports of high-nuclear transition metal clusters with thiol groups in their periphery. In this work, a novel cluster, [Fe6O2(OH)2(O2CC6H4SCH3)10(hep)2]·CH3CN·CH2Cl2 (Fe6) has been constructed by coordinating an octahedral Fe(III) ion 4-mercaptobenzoate and hepH (hepH = 2-(2-hydroxyethyl) pyridine). The functionalized thiomethyl around the periphery Fe6 cluster may provide binding sites for surfaces some specific materials, such as noble metals. Therefore, silver nanoparticle...

10.1039/c3ce41444b article EN CrystEngComm 2013-10-22

A [111] facet dominated gold single crystal electrode with improved electrocatalytic ability for the oxidation of ethanol and nitrite.

10.1039/c8nj03235a article EN New Journal of Chemistry 2018-01-01

H2O2-related metabolites are essential indicators in clinical diagnosis because the accumulation of such reactive oxygen species could cause risk cardiovascular disease. Herein, we reported an electrochemical sensor to determine H2O2 and glucose. The pyrroloquinoline skeleton containing molecules (PQT) were used as electrocatalyst gold cavity array (GCA) electrodes supporting electrode. GCA electrode was fabricated by electrodeposition using high-ordered two-dimensional polystyrene spheres...

10.3390/nano12101770 article EN cc-by Nanomaterials 2022-05-23

A turn-on fluorescence probe PQP-1 with a pyrroloquinoline skeleton has been designed and synthesized. Probe showed high sensitivity to HSO3-, low detection limit (16.83 nM), wide linear range (50-3000 μM). More importantly, could distinguish between HSO3- SO32-. Furthermore, cell imaging experiments of in HeLa cells revealed that had potential application value biological systems.

10.1007/s44211-022-00126-2 article EN Analytical Sciences 2022-06-17

Objective: To evaluate the transcranial sonographic characteristics in patients with Parkinson's disease (PD) symptoms of restless legs syndrome (RLS). Methods: Patients diagnosis definite PD from Second Affiliated Hospital Soochow University and 3 other participating hospitals between September 2018 December 2019 were consecutively enrolled. Concurrent RLS determined using Non-motor Symptoms Questionnaire. Transcranial sonography (TCS) clinical assessments performed during same time related...

10.3760/cma.j.cn112137-20200907-02588 article EN Zhonghua yixue zazhi 2021-06-08
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