A5060378036- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Neonatal Respiratory Health Research
- Maternal and Perinatal Health Interventions
- Infant Development and Preterm Care
- Pharmaceutical studies and practices
- Ethics and Legal Issues in Pediatric Healthcare
- Assisted Reproductive Technology and Twin Pregnancy
- Systemic Sclerosis and Related Diseases
- Preterm Birth and Chorioamnionitis
- Ethics in Clinical Research
- Prenatal Screening and Diagnostics
- Global Health Workforce Issues
- Gestational Diabetes Research and Management
- Cancer Diagnosis and Treatment
- Neonatal and fetal brain pathology
- Anesthesia and Neurotoxicity Research
- Cancer Risks and Factors
- Endometrial and Cervical Cancer Treatments
Leiden University Medical Center
2011-2020
University Medical Center Groningen
2017-2020
Medisch Centrum Haaglanden
2020
Accreditation Council for Graduate Medical Education
2020
University of Groningen
2017
Leiden University
2011-2016
Amsterdam UMC Location University of Amsterdam
2012
University Medical Center Utrecht
2012
OLVG
2012
University Medical Center
2012
Studies have shown that fetal progenitor cells persist in maternal blood or bone marrow for more than 30 years after delivery. Increased trafficking of occurs during pregnancy complications, such as hypertension, preeclampsia, miscarriage and intra-uterine growth restriction (IUGR). Women with these complications are significantly often HLA-class II compatible their spouses. who later develop scleroderma also give birth to an child often. From prior studies we hypothesized preeclampsia other...
To evaluate caesarean section and adverse neonatal outcome rates after induction of labour or expectant management in women with an unripe cervix at near term.Secondary analysis data from two randomised clinical trials.Data were collected nationwide Dutch trials.Women hypertensive disease (HYPITAT trial) suspected fetal growth restriction (DIGITAT a Bishop score ≤6.Comparison outcomes management.Rates outcome, defined as 5-minute Apgar ≤6 and/or arterial umbilical cord pH <7.05 intensive...
Objective: The aim of this study was to growth patterns children born after suspected fetal restriction (FGR) at term and compare the effect induction labor (IoL) expectant management (EM), also in relation neurodevelopmental behavioral outcome age 2. Methods: We performed a 2 years' follow-up included Disproportionate Intrauterine Growth Restriction Trial Term (DIGITAT) study, Randomized Controlled (RCT) comparing IoL with EM pregnancies FGR term. collected data on child until years....
The disproportionate intrauterine growth intervention trial at term was an intention to treat analysis and compared labor induction with expectant monitoring in pregnancies complicated by fetal restriction showed equivalence for neonatal outcomes.To evaluate participation bias examine the generalizability of results obstetrical randomized trial.We used data from participants nonparticipants a controlled trial-the (n=1116) -to perform secondary analysis. This study management women...
A single case of neonatal organophosphate-like poisoning is presented, presumed to have been caused by traditional medicine intake. The dangers medications and naturally occurring anticholinergics are discussed. South African Journal Child Health Vol. 2 (1) 2008: pp. 26-27
The Disproportionate Intrauterine Growth Intervention Trial at Term (DIGITAT) was a randomized controlled trial that prospectively observed children with suspected intrauterine growth restriction (IUGR) term. DIGITAT designed to investigate whether induction of labor for pregnancies IUGR beyond 36 weeks gestation reduced neonatal morbidity and mortality compared an expectant approach fetal maternal surveillance. Data from showed no significant differences between the 2 approaches in primary...
( BJOG . 2016;123(9):1501–1508) Between 20% and 25% of pregnancies involve induction labor (IOL), with the intervention indicated when conditions exist where a better outcome for mother and/or child would be expected if pregnancy is not further prolonged. However, effectiveness IOL debatable, especially in setting an unripe cervix, studies indicating associated high rate cesarean section (CS). The objective this study was to evaluate CS adverse neonatal rates versus expectant management...