- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Neonatal Respiratory Health Research
- Gestational Diabetes Research and Management
- Assisted Reproductive Technology and Twin Pregnancy
- Prenatal Screening and Diagnostics
- Pregnancy and Medication Impact
- Maternal and fetal healthcare
- Global Maternal and Child Health
- Preterm Birth and Chorioamnionitis
- Delphi Technique in Research
- Reproductive System and Pregnancy
- Maternal and Perinatal Health Interventions
- Autopsy Techniques and Outcomes
- Infant Development and Preterm Care
- Neonatal and fetal brain pathology
- Cardiovascular Issues in Pregnancy
- Cancer Risks and Factors
- Grief, Bereavement, and Mental Health
- Pregnancy-related medical research
- Ectopic Pregnancy Diagnosis and Management
- Congenital Diaphragmatic Hernia Studies
- Hormonal Regulation and Hypertension
- Drug Transport and Resistance Mechanisms
- Pediatric Urology and Nephrology Studies
University of Groningen
2016-2025
University Medical Center Groningen
2016-2025
Dialyse Centrum Groningen
2024
Mount Sinai Hospital
2016-2022
Flinders Medical Centre
2022
Monash University
2022
Baylor College of Medicine
2022
Royal College of Pathologists
2022
Case Western Reserve University
2022
Yale University
2022
-The value of placental examination in investigations adverse pregnancy outcomes may be compromised by sampling and definition differences between laboratories.-To establish an agreed-upon protocol for the placenta, diagnostic criteria lesions. Recommendations would cover reporting placentas tertiary centers as well community hospitals district general hospitals, are also relevant to scientific research community.-Areas controversy or uncertainty were explored prior a 1-day meeting where...
Objective To determine, by expert consensus, a definition for early and late fetal growth restriction (FGR) through Delphi procedure. Method A survey was conducted among an international panel of experts on FGR. Panel members were provided with 18 literature-based parameters defining FGR asked to rate the importance these diagnosis both 5-point Likert scale. Parameters described as solitary (parameters that are sufficient diagnose FGR, even if all other normal) contributory require abnormal...
ABSTRACT Objectives Twin pregnancy complicated by selective fetal growth restriction (sFGR) is associated with increased perinatal mortality and morbidity. Inconsistencies in the diagnostic criteria for sFGR employed existing studies hinder ability to compare or combine their findings. It therefore challenging establish robust evidence‐based management monitoring pathways these pregnancies. The main aim of this study was determine, expert consensus using a Delphi procedure, key features...
Severe early onset fetal growth restriction caused by placental dysfunction leads to high rates of perinatal mortality and neonatal morbidity. The phosphodiesterase 5 inhibitor, sildenafil, inhibits cyclic guanosine monophosphate hydrolysis, thereby activating the effects nitric oxide, might improve uteroplacental function subsequent outcomes.
Abstract Early development of the gut ecosystem is crucial for lifelong health. While infant bacterial communities have been studied extensively, virome remains under-explored. To study over time and factors that shape it, we longitudinally assess composition viruses their hosts in 30 women during after pregnancy 32 infants first year life. Using shotgun metagenomic sequencing applied to dsDNA extracted from Virus-Like Particles (VLPs) bacteria, generate 205 VLP metaviromes 322 total...
To introduce the pathophysiological Tulip classification system for underlying cause and mechanism of perinatal mortality based on clinical pathological findings purpose counselling prevention.Descriptive.Tertiary referral teaching hospital.Perinatally related deaths.A consisting groups death was drawn up by a panel through causal analysis events to death. Individual performed assessors. Panel discussions were held cases without consensus.Inter-rater agreement death.The consists six main...
A carefully classified dataset of perinatal mortality will retain the most significant information on causes death. Such is needed for health care policy development, surveillance and international comparisons, clinical services research. For comparability purposes, we propose a classification system that could serve all these needs, be applicable in both developing developed countries. It to adhere basic concepts underlying cause International Classification Diseases (ICD), although gaps...
Stillbirths need to count. They constitute the majority of world's perinatal deaths and yet, they are largely invisible. Simply counting stillbirths is only first step in analysis prevention. From a public health perspective, there for information on timing circumstances death, associated conditions underlying causes, availability quality care. This will guide efforts prevent improve In this report, we assess how different definitions limits registration affect data capture, discuss specific...
Assessments of maternal near miss (MNM) are increasingly used in addition to those mortality measures. The World Health Organization (WHO) has introduced an MNM tool 2009, but this was previously found be limited applicability several low–resource settings. aim study identify adaptations enhance the WHO sub–Saharan Africa. Using a Delphi consensus methodology, existing tools were rated for sub-Saharan Africa over series three rounds. Maternal health experts from or with considerable...
ABSTRACT Objectives To explore the association between fetal umbilical and middle cerebral artery (MCA) Doppler abnormalities outcome in late preterm pregnancies at risk of growth restriction. Methods This was a prospective cohort study singleton restriction 32 + 0 to 36 6 weeks gestation, enrolled 33 European centers 2017 2018, which MCA velocimetry performed. Pregnancies were considered if they had estimated weight and/or abdominal circumference (AC) < 10 th percentile, abnormal...
We welcome the global stillbirth estimates published by UNICEF and WHO in October, 2020.1United Nations Inter-agency Group for Child Mortality EstimationA neglected tragedy: burden of stillbirths.https://data.unicef.org/resources/a-neglected-tragedy-stillbirth-estimates-report/Date accessed: October 23, 2020Google Scholar These data indicate that there are at least 1·9 million stillbirths globally each year. The heavy public health has long remained invisible, despite more than a decade...
<h3>Importance</h3> Chemotherapy during the first trimester of pregnancy should be avoided owing to risk congenital malformations. However, precise gestational age at which chemotherapy can initiated safely remains unclear. <h3>Objective</h3> To assess malformation rates associated with initiation among pregnant women cancer. <h3>Design, Setting, and Participants</h3> This multicenter cohort study evaluated all who received between 1977 2019 registered in International Network on Cancer,...