- Infant Development and Preterm Care
- Obesity, Physical Activity, Diet
- Birth, Development, and Health
- Neonatal Respiratory Health Research
- Child and Adolescent Health
- Health disparities and outcomes
- Nutritional Studies and Diet
- Child and Adolescent Psychosocial and Emotional Development
- Romani and Gypsy Studies
- Maternal Mental Health During Pregnancy and Postpartum
- Neonatal and fetal brain pathology
- Smoking Behavior and Cessation
- Youth Substance Use and School Attendance
- Child Nutrition and Water Access
- Health Promotion and Cardiovascular Prevention
- Maternal and Perinatal Health Interventions
- School Health and Nursing Education
- Breastfeeding Practices and Influences
- Cardiovascular Health and Risk Factors
- Noise Effects and Management
- Global Public Health Policies and Epidemiology
- Family and Disability Support Research
- Migration, Health and Trauma
- Prenatal Substance Exposure Effects
- demographic modeling and climate adaptation
University Medical Center Groningen
2016-2025
University of Groningen
2018-2025
KU Leuven
2022-2025
Erasmus MC - Sophia Children’s Hospital
2019-2025
Departement Omgeving
2024
Erasmus MC
2015-2022
Erasmus University Rotterdam
1999-2021
Geneeskundige en Gezondheidsdienst
2016
Amsterdam UMC Location Vrije Universiteit Amsterdam
2008-2015
Amsterdam Public Health
2010-2014
Abstract Early development of the gut ecosystem is crucial for lifelong health. While infant bacterial communities have been studied extensively, virome remains under-explored. To study over time and factors that shape it, we longitudinally assess composition viruses their hosts in 30 women during after pregnancy 32 infants first year life. Using shotgun metagenomic sequencing applied to dsDNA extracted from Virus-Like Particles (VLPs) bacteria, generate 205 VLP metaviromes 322 total...
Complications of overweight amplify with age, and irreversible damage already exists in young persons. Identifying the most sensitive age interval(s) for adult is relevant primary prevention. The aim study was to assess relative contribution body mass index (BMI) changes between 0 18 years overweight, identify earliest critical growth period.Data from 762 subjects Terneuzen Birth Cohort an average 21 measurements per subject birth until were used. main outcome measure BMI standard deviation...
Objective To examine the diversity in paediatric vision and hearing screening programmes Europe. Methods Themes for comparison of derived from literature were used to compile three questionnaires on vision, hearing, public health screening. Tests used, professions involved, age, frequency testing seem influence sensitivity, specificity, costs most. Questionnaires sent ophthalmologists, orthoptists, otolaryngologists, audiologists involved all EU full-member, candidate, associate states....
Parental divorce is one of the most stressful life events for youth and often associated with (long-lasting) emotional behavioral problems (EBP). However, not much known about timing emergence these EBP in adolescents relative to moment parental divorce, its longitudinal effects. We therefore assessed this used first four waves TRacking Adolescent's Individual Lives Survey (TRAILS) cohort, which included 2230 10-12 years olds at baseline. were measured through Youth Self-Report (YSR), as...
The gut microbiome is involved in the bi-directional relationship of – brain axis. As most studies this are small and do not account for use psychotropic drugs (PTDs), we explored relations with several internalizing disorders, while adjusting PTDs other relevant medications, 7,656 Lifelines participants from Northern Netherlands (5,522 controls 491 at least one disorder). Disorders included dysthymia, major depressive disorder (MDD), any (AnyDep: dysthymia or MDD), generalized anxiety (GAD)...
Background We recently reported the age interval 2–6y being earliest and most critical for adult overweight. now aim to determine which intervals are predictive of cardiometabolic risk at young adulthood. Methods Findings analyzed data from 642 18–28 years olds Terneuzen Birth Cohort. Individual BMI SDS trajectories were fitted by a piecewise linear model. By multiple regression analyses relationships assessed between subsequent conditional changes components metabolic syndrome (MetS),...
Geographical inequalities in perinatal health and child welfare require attention. To improve the identification, care, of mothers young children at risk adverse outcomes, HP4All-2 program was developed. The consists three studies, focusing on creating a continuum for selection tailored care pathways from preconception antenatal towards 1) postpartum 2) early childhood as well 3) interconception care. has been implemented ten municipalities Netherlands, aiming to target communities with...
In literature, not much emphasis has been placed on methods for analyzing repeatedly measured independent variables, even less so the use in prediction modeling specifically. However, repeated measurements could especially be interesting construction of models. Therefore, our objective was to evaluate different model a variable and long-term fixed outcome into model. Six handle predictor were applied develop Methods evaluated with respect models' predictive quality (explained variance R2...
Background Roma living in marginalized communities often face poor conditions and material deprivation, which may negatively impact parenting. Our aim is to compare the parenting behavior (support, harsh discipline, stimulation) of mothers from majority population Slovakia. We also examine role socioeconomic disadvantage related worries differences between these groups. Methods obtained cross-sectional data children aged 14–18 months using first wave longitudinal RomaREACH study dataset. Two...
Introduction: While the World Health Organization (WHO) advocates organizing maternity care and preventive child healthcare (PCHC) as people-centred, integrated services, globally these services are often established separately, causing discontinuity of care. Our aim is to synthesize evidence concerning what impacts parents’ experience continuity care, how promote it. Methods: Qualitative systematic review. Embase, Medline, Web Science, Cochrane, CINAHL Google Scholar were searched for...
Introduction Preterm born children are at a higher risk for refractive errors. A long duration of screen time and activities with short working distance (≤30 cm) may further add to the increased risk. The aim this study was assess separate combined effects preterm birth on spectacle wear among 5-year-olds adolescents. Methods We analyzed data from community-based cohort study, part Longitudinal Outcome Project (LOLLIPOP). Early preterm-born (EP < 32 weeks), moderately-late (MLP 32–36...
Objective: We aimed to investigate the feasibility of live-performed music therapy for extremely and very preterm infants admitted neonatal intensive care unit (NICU), their parents, starting 1st-2nd week after birth. They may benefit from as comforting non-pharmacological intervention. Study Design: included born before 30 weeks' gestation in a single center NICU study. Live-performed was provided three times per week, tailored infant's medical condition. Parents were actively involved....
Abstract Background Educational inequalities in metabolic syndrome (MetS) are a growing public health concern. Intervening on modifiable factors may help reduce these inequalities, but there is need for evidence the long-term impact of intervening factors. Thus, we simulate development educational MetS across life course and assess that contribute to inequalities. Methods We used data from prospective multigenerational Dutch Lifelines Cohort Study estimate required input continuous-time...
Breastfeeding (BF) is protective against overweight and associated with dietary behaviour. The aims of our study were to assess the relationship between exclusive BF duration BMI, waist circumference (WC) waist-hip ratio (WHR) at adulthood, whether behaviour could explain proxies fat mass. In 2004-2005, 822 subjects from Terneuzen Birth Cohort (n = 2,604), aged 18-28 years, filled in postal questionnaires including sociodemographic factors aspects (dietary pattern, consumption fruit...
Background TV time and total sedentary have been positively related to biomarkers of cardiometabolic risk in adults. We aim examine the association computer separately with young Additionally, mediating role waist circumference (WC) is studied. Methods Findings Data 634 Dutch adults (18–28 years; 39% male) were used. Cardiometabolic included indicators overweight, blood pressure, levels fasting plasma insulin, cholesterol, glucose, triglycerides a clustered score. Linear regression analyses...
The perception of healthy growth and weight may differ between cultures, which could influence feeding practises consequently affect the development overweight. present study examined ethnic variation in maternal perceptions their on among Turkish Dutch infants aged 0–6 months. Data were obtained from mothers 143 healthy, singleton, term with birth weights appropriate for gestational age, using structured interviews at 1, 4 6 months after birth. Compared mothers, descent perceived a chubby...
Having an infant in the neonatal intensive care unit (NICU) elicits maternal anxiety, which may hamper parent−child bonding. We performed a prospective cohort study to describe anxiety mothers of infants born before 30 weeks gestation during NICU stay The Netherlands, and investigated influence stress gestational age. Second, we randomized-controlled live-performed music therapy trial (LPMT trial) investigate whether applied alleviated anxiety. relation between stress, age, was measured 45...
Understanding the course of stress during neonatal intensive care unit stay may provide targets for interventions. Our aim was to describe in preterm infants first 28 days life, influence gestational age, and associations with clinical characteristics.In a single centre prospective cohort study, we included age <30 weeks and/or birth weight <1,000 g. We measured over using Neonatal Infant Stressor Scale (NISS). plotted daily NISS total subcategory scores by age. The subcategories were (1)...
Introduction The association between neonatal intensive care unit (NICU) related stress in preterm infants and their health-related quality of life (HRQoL) the first year following birth remains unexplored. Understanding this is crucial for enhancing preventive supportive measures parents within beyond NICU. Methods From a single center observational cohort study, we included with gestational ages below 30 weeks and/or weights under 1,000 grams. HRQoL was quantified using Infant Quality Life...