A5091465640- Kidney Stones and Urolithiasis Treatments
- Biomedical Research and Pathophysiology
- Parathyroid Disorders and Treatments
- Porphyrin Metabolism and Disorders
- Dialysis and Renal Disease Management
- Pediatric Urology and Nephrology Studies
- Therapeutic Uses of Natural Elements
- Renal function and acid-base balance
- Metabolism and Genetic Disorders
- Paleopathology and ancient diseases
- Dermatological and Skeletal Disorders
- Pharmacological Effects and Toxicity Studies
- Potassium and Related Disorders
- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Vitamin D Research Studies
- Renal Transplantation Outcomes and Treatments
- Neurological and metabolic disorders
- Medication Adherence and Compliance
- Magnesium in Health and Disease
- Vaccine Coverage and Hesitancy
- Electroconvulsive Therapy Studies
- Pharmaceutical Practices and Patient Outcomes
- Urological Disorders and Treatments
- Venous Thromboembolism Diagnosis and Management
A. O. Ordine Mauriziano di Torino
2006-2024
University of L'Aquila
2024
IRCCS Humanitas Research Hospital
2024
Ospedale San Giovanni Bosco
2008
Policlinico Umberto I
2002-2003
Ospedali Riuniti Umberto I
1996-1999
Pediatric Nephrology of Alabama
1993
1. To assess whether the mineral content of drinking water influences both risk stone formation and bone metabolism in idiopathic calcium nephrolithiasis, 21 patients were switched from their usual home diets to a 10 mmol calcium, low-oxalate, protein-controlled diet, supplemented with three different types water. Drinking added 1, 6 20 0.5, 50 bicarbonate respectively controlled diet. 2. The study periods lasted 1 month each separated by day washout interval. Blood urine chemistries,...
The occurrence of chronic renal insufficiency was investigated in 171 patients with severe idiopathic calcium stone disease. Ninety healthy subjects matched for age and sex were used as controls. thereafter subclassified into two subgroups, assuming a GFR 80 ml/min/1.73 m2 body surface area cut-off value: the normal GFR, 141patients, impaired 30 patients. group included more males younger both at onset presentation. In disease lasted longer, but overall stones recurrence rate high those...
Summary— Oxalate excretion was measured in healthy subjects and idiopathic calcium stone‐formers on dietary regimens which differed the type amount of protein allowed; 24‐h urine collections were obtained from 41 practising vegetarians 40 normal persons a free, mixed, “mediterranean” diet. Twenty also studied while two low calcium, oxalate diets that animal high one restricted other. Vegetarians had higher urinary levels than controls although markedly lower, saturation with calcium/oxalate...
A considerable minority of patients on waiting lists for kidney transplantation either have no diagnosis (and fall into the subset undiagnosed cases) because biopsy was not performed or histological findings were non-specific, do any well-defined clinical category. Some these might be affected by a previously unrecognised monogenic disease.Through multidisciplinary cooperative effort, we built an analytical pipeline to identify with chronic disease (CKD) suspicion condition without...
1. The serum oxalate concentration rises in chronic renal failure and it is only partially eliminated by regular dialysis treatment. However, the recent literature not conclusive on whether progressive retention secondary oxalosis should be expected patients 2. To further investigate this, we have estimated state of saturation with respect to calcium mono-hydrate plasma ultrafiltrates from 28 maintenance haemodialysis eight healthy control subjects, matched for sex age. Five had type I...
No AccessJournal of Urology1 Sep 1992Plasma and Urine Glycolate Assays for Differentiating the Hyperoxaluria Syndromes Martino Marangella, Michele Petrarulo, Corrado Vitale, Domenico Cosseddu, Franco Linari MarangellaMartino Marangella , PetraruloMichele Petrarulo VitaleCorrado Vitale CossedduDomenico Cosseddu LinariFranco View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)36796-4AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints...
Regular dialysis treatment (RDT) does not obviate hyperoxalemia of chronic renal failure (CRF). However, there is emerging evidence suggesting that current prescription always associated to progressive oxalate accumulation. In view the controversy still concerning this issue, we have investigated on plasma profiles and kinetics in patients RDT. Oxalate was determined by ion chromatography serum ultrafiltrates whole dialyzate 23 stable RDT for end-stage unrelated primary hyperoxaluria. Nine...
Abstract We use oxalate oxidase from barley seedlings for the colorimetric determination of in plasma. The is converted to hydrogen peroxide, which, presence peroxidase, detected by a Trinder-like chromogenic system. Optimization assay, including deproteinization and elimination interferences reducing substrates, described. Ascorbate additions (200 mumol/L) did not affect concentration plasma, even after long frozen storage. Mean analytical recovery averaged 102% +/- 6.9%, imprecision (CV)...
Burosumab is a monoclonal anti-FGF23 antibody used to treat patients with X-linked hypophosphatemic rickets (XLH). Its effect on serum phosphate and physical performance was compared in during 6-month treatment burosumab. Eight adult XHL were treated burosumab (1 mg/kg s.c. every 28 days). In the first 6 months of treatment, calcium-phosphate metabolism variables measured, muscle (tested chair walking test) quality life fatigue, BPI-pain BPI-life questionnaires) estimated. A significant...
Citrate is a relevant component of the inhibitory potential urine environment. Its excretion and renal handling have been widely studied in subjects with normal function, but little known about changes induced by chronic insufficiency. We investigated citrate 50 patients different degrees insufficiency as compared to 30 healthy function. Among 34 were defined having mild based on GFR 80 through 40 ml/min/1.73 m2 BSA, while 16 had moderate-to-severe failure, ranging from 20 BSA. Serum...
We report herein a domino orthotopic liver transplantation (LT), from 38-year-old woman undergoing liver-kidney (LKT) for primary hyperoxaluria type I (PH1) to recipient with cirrhosis and hepatocellular carcinoma. Delayed onset of PH1 renal failure 10% residual alanine-glyoxylate aminotransferase (AGT) activity in justified its use procedure. The clinical course after LKT was similar that described other series, including ours. Renal function started promptly maintained despite sustained...
Abstract Estimation of state saturation with stone-forming salt represents a reliable tool to assess the overall risk. The available methods are based on computer-assisted ab initio calculations. Our earlier method URSUS was subsequently substituted by Lithorisk®, software including visualization risk profiles. Unfortunately, Lithorisk does not adapt new versions Windows® and Macintosh® Apple, neither runs smartphones or tablets. We propose novel version which can be directly used online any...
Dabigatran is an oral direct inhibitor indicated for stroke prevention in patients with atrial fibrillation. Unlike warfarin, dabigatran's observed therapeutic window and minimal drug-to-drug interaction suggest that laboratory test dose adjustments are not necessary; nevertheless, circumstances of excessive anticoagulation, decreased kidney function, instances significant bleeding thrombosis require assessment. In order to gather experience the management global [activated partial...
Primary hyperoxalurias (PHs) are rare autosomal recessive diseases of the glyoxylate metabolism; PH1 is caused by mutations in AGXT gene, PH2 GRHPR and PH3 HOGA1.Here we report first large multi-center cohort Italian PH patients collected over 30 years (1992-2020 median follow-up time 8.5 years). Complete genotype was available for 94/95 all (n = 3) 5) patients. Symptoms at onset were mainly nephrolithiasis (46.3%) nephrocalcinosis (33.7%). Median age symptoms diagnosis 4.0 9.9 years,...