A5100783143- Gut microbiota and health
- Air Quality and Health Impacts
- Immune cells in cancer
- Electrospun Nanofibers in Biomedical Applications
- Ginseng Biological Effects and Applications
- Tissue Engineering and Regenerative Medicine
- Heavy Metal Exposure and Toxicity
- Cryptography and Data Security
- Animal testing and alternatives
- 3D Printing in Biomedical Research
- Silk-based biomaterials and applications
- Mycobacterium research and diagnosis
- Gene Regulatory Network Analysis
- interferon and immune responses
- Barrier Structure and Function Studies
- Advanced Authentication Protocols Security
- Cryptographic Implementations and Security
- Adipose Tissue and Metabolism
- Liver Disease Diagnosis and Treatment
- Effects and risks of endocrine disrupting chemicals
- Pluripotent Stem Cells Research
- Osteoarthritis Treatment and Mechanisms
- Heavy metals in environment
- Immune Response and Inflammation
- Adipokines, Inflammation, and Metabolic Diseases
Ningbo Medical Center Lihuili Hospital
2025
Ningbo University
2025
China People's Public Security University
2024
University of Hong Kong
2017-2022
Zhujiang Hospital
2022
Southern Medical University
2022
Unilever (United Kingdom)
2018
Chinese University of Hong Kong
2006-2017
Second Hospital of Shanxi Medical University
2017
Shanxi Medical University
2017
Adipose tissue macrophage (ATM) inflammation is involved with meta-inflammation and pathology of metabolic complications. Here we report that in adipocytes, elevated lactate production, previously regarded as the waste product glycolysis, serves a danger signal to promote ATM polarization an inflammatory state context obesity. Adipocyte-selective deletion dehydrogenase A (Ldha), enzyme converting pyruvate lactate, protects mice from obesity-associated glucose intolerance insulin resistance,...
Abstract The gut microbiota has the potential to influence efficacy of cancer therapy. Here, we investigated contribution intestinal microbiome on treatment outcomes in a heterogeneous cohort that included multiple types identify microbes with global impact immune response. Human metagenomic analysis revealed responder patients had significantly higher microbial diversity and different compositions compared non-responders. A machine-learning model was developed validated an independent...
Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) have an irreplaceable role in the treatment of myocardial infarction (MI), which can be injected into transplanted area with new (Cardiomyocytes, CMs), and improve function. However, immaturity structure function iPSC-CMs is main bottleneck at present. Since collagen participates formation extracellular matrix (ECM), we synthesized nano colloidal gelatin (Gel) as component, confirmed that biomaterial has good biocompatibility...
We investigated environmental lead pollution and its impact on children's blood levels (BLLs) in a rural area of China.In 2007, we studied 379 children younger than 15 years living 7 villages near mines processing plants, along with control group 61 from another village. determined their BLLs collected samples, personal data, information other potential exposures. followed approximately 86% the who had high (> μg/dL) for 1 year. factors influencing by multivariate linear regression.Lead...
A TRIF-dependent pathway that restricts viral infection also prevents diet-induced hepatic steatosis.
In the field of criminal justice in China, there has been ongoing debate over application natural interpretation and discretion. This paper first discusses surrounding from perspective law, clarifying nature as a reason for rather than method interpretation. It elaborates on three bases interpretation: progressive logical relationships, sameness things, necessity legal application. Secondly, using case Wang Chengxue an example, clarifies misuse judicial practice. Regarding discussion...
Gut microbiota is involved in both onset and progression of obesity. Obesity associated with several cardiovascular diseases, among which atherosclerosis the leading cause morbidity mortality. However, role gut obesity-related complication remains to be explored. We found that fecal amount Akkermansia municiphila (Akk), a beneficial bacterium, decreased apolipoprotein E-deficient (apoE -/-) mice fed Western diet. In this study, we investigated whether Akk may exert against development...