A5012243758- Electrospun Nanofibers in Biomedical Applications
- Antimicrobial agents and applications
- Tissue Engineering and Regenerative Medicine
- Wound Healing and Treatments
- Silk-based biomaterials and applications
- Bone Tissue Engineering Materials
- 3D Printing in Biomedical Research
- Ocular Surface and Contact Lens
- Nanoparticles: synthesis and applications
- Nanoparticle-Based Drug Delivery
- RNA Interference and Gene Delivery
- Advanced Drug Delivery Systems
- Surgical Sutures and Adhesives
- biodegradable polymer synthesis and properties
- Bacterial biofilms and quorum sensing
- Corneal surgery and disorders
- Gold and Silver Nanoparticles Synthesis and Applications
- Photodynamic Therapy Research Studies
- Corneal Surgery and Treatments
- Molecular Biology Techniques and Applications
- Luminescence Properties of Advanced Materials
- Nanoplatforms for cancer theranostics
- Connective tissue disorders research
- Antimicrobial Peptides and Activities
- Cellular Mechanics and Interactions
Ningbo University
2019-2025
Ningbo Medical Center Lihuili Hospital
2023-2025
Abstract Antibacterial photodynamic therapy (aPDT) and antibacterial sonodynamic (aSDT) utilize sensitizers (photosensitizers/sonosensitizers) to produce reactive oxygen species (ROS) for treatment under the stimulation of light/ultrasound, which have characteristics broad‐spectrum properties, low drug‐resistance, effective targeting infected tissues. Nanomaterials in aPDT/aSDT are primarily used as nano‐sensitizers or nano‐carriers sensitizers. They enhance stability permeability...
This paper summarizes the preparation processes of tailored chitosan-based hydrogels, along with their specific applications in bone regeneration, aiming to inspire innovative designs for hydrogels and foster expanded applications.
A series of hydrogels containing guanidine-based polymers using a poloxamer as the matrix were prepared to provide novel wound dressings with antibacterial and repairing-promotion properties for skin wounds. Herein, we developed hydrogels, cationic polymer polyhexamethylene guanidine hydrochloride (PHMG) aqueous solution (12%, w/w) simplified PHMGP, chitosan (CS)-cross-linked PHMG (referred PHMC) PHMCP, hyaluronic acid (HA)-modified PHMH) PHMHP, enhancing full-thickness healing. The...
Smooth muscles play a vital role in peristalsis, tissue constriction, and relaxation but lack adequate self-repair capability for addressing extensive muscle defects. Engineering scaffolds have been broadly proposed to repair the tissue. However, efforts date shown that those engineered focus on cell alignment 2-dimension (2D) fail direct cells align 3D area, which is irresolvable remodel architecture restore functions like contraction relaxation. Herein, we introduced an iron oxide (Fe 3 O...
When dAME is used to treat the cornea damaged by acid burn, it helpful reduce damage seriousness and opacity degree, which for maintaining tissue architecture function.
Engineered scaffolds are used for repairing damaged esophagus to allow the precise alignment and movement of smooth muscle peristalsis. However, most these focus solely on inducing cell through directional apparatus, often overlooking promotion tissue formation causing reduced esophageal repair effectiveness. To address this issue, we first introduced aligned nano-ferroferric oxide (Fe3O4) assemblies a micropatterned poly(ethylene glycol) (PEG) hydrogel form micro-/nano-stripes. Further...
The nanotechnology using biodegradable polymer carriers with good biocompatibility and bioabsorbability has been much studied applied in drug delivery system biomedical engineering. In this work, the triblocked oligomer poly(L-lactide)-b-poly(ethylene glycol)-b-poly(L-lactide) (PLEL) molecular weight of ~20.0 KDa was firstly synthesized. Its chemistry characterized hydrogen nuclear magnetic resonance (1H-NMR) spectrum Fourier transform infrared (FTIR) spectroscopy. Subsequently,...
Because of their unique and excellent properties, gold nanoparticles (GNPs) have been widely used in biological monitoring, cosmetics clinical fields. In this study, PEG200, as a component, ascorbic acid, reducing agent, were to develop rapid one-step method for GNPs synthesis at room temperature. The effect PEG200 on tolerance some common solvents also investigated. whole process was completed within one hour, transmission electron microscope (TEM), dynamic light scattering (DLS) UV-Vis...