A5000868691- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Epigenetics and DNA Methylation
- Cancer-related gene regulation
- MicroRNA in disease regulation
- Head and Neck Cancer Studies
- Ferroptosis and cancer prognosis
- Cancer Immunotherapy and Biomarkers
- Tracheal and airway disorders
- Electrospun Nanofibers in Biomedical Applications
- Circular RNAs in diseases
- Cleft Lip and Palate Research
- biodegradable polymer synthesis and properties
- Tissue Engineering and Regenerative Medicine
- Cholangiocarcinoma and Gallbladder Cancer Studies
- RNA Research and Splicing
- Head and Neck Surgical Oncology
- Immune cells in cancer
- Ear Surgery and Otitis Media
- Peptidase Inhibition and Analysis
- Wound Healing and Treatments
- Cancer Cells and Metastasis
- Cancer, Hypoxia, and Metabolism
- Voice and Speech Disorders
- Cancer Genomics and Diagnostics
Ningbo Medical Center Lihuili Hospital
2016-2025
Ningbo University
2016-2025
Affiliated Hospital of Jining Medical University
2025
China University of Geosciences (Beijing)
2024
Hong Kong Polytechnic University
2023
Ningbo No. 2 Hospital
2021
Stone Clinic
2021
Weatherford College
2019
Ningbo Institute of Industrial Technology
2015
Chinese Academy of Sciences
2015
Osteoporosis, a metabolic bone disease characterized by low mineral density and deterioration of microarchitecture, has led to high risk fatal osteoporotic fractures worldwide. Accumulating evidence revealed that sexual dimorphism is notable feature osteoporosis, with sex-specific differences in epidemiology pathogenesis. Specifically, females are more susceptible than males while prone disability or death from the disease. To date, sex chromosome abnormalities steroid hormones have been...
Most countries worldwide, especially low- and middle-income (LMICs), are facing an increasing prevalence of fast-food consumption multiple burdens malnutrition among young adolescents.To compare the adolescents in LMICs.We used data from most recent Global School-Based Student Health Survey (2009-2015), which had been collected using a standardized questionnaire. The weighted 95% confidential intervals were calculated overall subgroups stratified by age, sex, nutritional status. pooled...
Chitosan/gelatin composite hydrogels with high strength are prepared by a precipitation method, possess controlled structures and biodegradability, support chondrocyte adhesion growth, may have potentials to cartilage tissue engineering.
Long non-coding RNAs (lncRNAs) are novel transcripts that may play important roles in cancer. Our study aimed to resolve the lncRNA profile of larynx squamous cell carcinoma (LSCC) and determine its clinical significance. The global expression LSCC tissues was measured by microarray. Distinctly expressed lncRNAs were identified levels AC026166.2-001 RP11-169D4.1-001 87 samples paired adjacent normal tissue analyzed real-time quantitative reverse transcriptase-polymerase chain reaction...
DNA methylation plays an important role in the etiology and pathogenesis of head neck squamous cell carcinoma (HNSCC). The current study aimed to identify aberrantly methylated-differentially expressed genes (DEGs) by a comprehensive bioinformatics analysis. In addition, we screened for DEGs affected modification further investigated their prognostic values HNSCC. We included microarray data (GSE25093 GSE33202) gene expression (GSE23036 GSE58911) from Gene Expression Omnibus. Aberrantly...
Diols or acids with different skeletal structures could be used to polymerize 2,5-furandicarboxylic acid (FDCA) in order adjust the properties of FDCA-based polyesters. A series FDCA polyesters similar structure as poly(propylene furandicarboxylate) (PPF) were prepared from and 1,3-propanediols containing substituent groups. The effect groups on thermal gas barrier behaviors investigated by differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), dynamic mechanical (DMA),...
This work provides an in-depth molecular structure design strategy for developing high-barrier polymer packaging films. A series of high-performance PPDThF copolyesters were prepared by utilizing the unique crystallization ability poly(propylene 2,5-thiophenedicarboxylate) (PPThF), as well a long-chain dicarboxylic acid, namely dodecanedioic acid (DA). The incorporation polyethylene-like polyester from DA into main chain polymers has been found to be random copolymerization, leading limited...
Abstract Bio‐based polyethylene furandicarboxylate (PEF) plays a vital role in high‐performance packaging material for plastic replacement. However, the poor toughness blocks its practical applications. Copolymerization modification can enhance of PEF but inevitably causes decrease strength and barrier properties. Although nanofillers overall performance PEF, intrinsic incompatibility between inert inorganic nanomaterials leads to reinforcement effects. Herein, polydopamine (PDA)...
The optimal management of perianal abscess ( PA) in infants remains controversial. This study aimed to compare incision and drainage (ID), with primary fistulotomy (IDF), conservative management(CM)for the treatment PA (< 1 year). A retrospective cohort was conducted for between 2014 2020. Patients undergoing IDF were assigned group, those ID whose parents declined surgery CM group. total 597 patients identified (591 boys 6 girls); 282 162 153 median age at first visit 43 days (range 30–90...
ABSTRACT Background Laryngeal squamous cell carcinoma (LSCC) is one of the most prevalent malignancies head and neck region. Circular RNAs (circRNAs) have been found to exhibit abnormal expression patterns in various tumors play pivotal roles tumorigenesis tumor progression. Methods Functional assays assessed proliferation, migration, invasion. Mechanistic studies were performed explore interaction between circTUBD1 heterogeneous nuclear ribonucleoprotein K (hnRNPK), as well its regulation...
MicroRNAs (miRNAs), the endogenous noncoding RNAs, are involved in carcinogenesis. Laryngeal squamous cell carcinoma (LSCC) is common cancer head and neck. Whether miRNAs can be used diagnosis of LSCC largely unknown. The purpose this study was to identify whether could use as potential biomarkers for diagnosis. expression levels miR-21, miR-106b miR-375, tissues paired nontumor were first quantitatively analyzed by reverse transcription-polymerase chain reaction. Then, relationships between...
Head and neck squamous cell carcinoma (HNSCC) rank among the most prevalent types of head cancer globally. Unfortunately, a significant number patients receive their diagnoses at advanced stages, limiting effectiveness available treatments. The tumor microenvironment (TME) is pivotal player in HNSCC development, with macrophages holding central role. Macrophages demonstrate diverse functions within TME, both inhibiting facilitating progression. M1 are characterized by phagocytic immune...
Integrin α5 (ITGA5) was involved in a variety of cancers. However, the role ITGA5 laryngeal squamous cell carcinoma (LSCC) remains unknown.The expression and corresponding clinicopathological parameters LSCC patients TCGA database. Five datasets (GSE51985, GSE59102, GSE84957, GSE27020, GSE65858) were downloaded from GEO database as validation sets. Kaplan-Meier plotter, Cox regression analysis, nomogram performed to determine prognostic value LSCC. GO, KEGG, GSEA used explore underlying...
tRNA-derived small RNAs (tsRNAs) participate in several biological processes, including carcinogenesis. The correlations between tsRNAs and human cancers are attracting substantial attention. Nevertheless, the involvement of laryngeal squamous cell carcinoma (LSCC) progression remains unclear. We constructed expression profiles LSCC adjacent normal tissues by next-generation sequencing. Interestingly, we identified a specific 5′-tiRNA fragment (tRF-33-Q1Q89P9L842205) that was significantly...