A5100632994- Neural and Behavioral Psychology Studies
- Visual perception and processing mechanisms
- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- EEG and Brain-Computer Interfaces
- Face Recognition and Perception
- Spatial Neglect and Hemispheric Dysfunction
- Visual Attention and Saliency Detection
- Transcranial Magnetic Stimulation Studies
- Mental Health Research Topics
- Vestibular and auditory disorders
- Memory and Neural Mechanisms
- Pain Management and Placebo Effect
- Neurobiology of Language and Bilingualism
- Neuroscience and Music Perception
- Glaucoma and retinal disorders
- Virtual Reality Applications and Impacts
- Decision-Making and Behavioral Economics
- Multisensory perception and integration
- Advanced Vision and Imaging
- Action Observation and Synchronization
- Creativity in Education and Neuroscience
- Advanced Graph Neural Networks
- Morphological variations and asymmetry
- Advanced Optical Imaging Technologies
Ningbo No. 2 Hospital
2025
University of Electronic Science and Technology of China
2016-2024
McGill University
2024
Henan University of Engineering
2024
Henan Psychiatric Hospital
2023
Xinxiang Medical University
2023
Ningbo University
2018-2023
Hainan University
2009-2023
Zhejiang University
2023
Cheongju University
2022
Background Graph theory and machine learning have been shown to be effective ways of classifying different stages Alzheimer’s disease (AD). Most previous studies only focused on inter-subject classification with single-mode neuroimaging data. However, whether this can truly reflect the changes in structure function brain region progression remains unverified. In current study, we aimed evaluate framework, which combines structural Magnetic Resonance Imaging (sMRI) resting-state functional...
Parkinson disease (PD) is a neurodegenerative characterized by selective loss of dopaminergic (DA) neurons in the midbrain. The regulatory role variety microRNAs PD has been confirmed, and our study first to demonstrate that miR-3473b involved regulation PD. In vitro, an inhibitor can inhibit secretion inflammatory factors (TNF-α IL-1β) moues microglia cell line (BV2) cells induced lipopolysaccharide (LPS) promote autophagy BV2 cells. vivo, antagomir activation substantia nigra pars compacta...
Using the Pearson correlation coefficient to constructing functional brain network has been evidenced be an effective means diagnose different stages of mild cognitive impairment (MCI) disease. In this study, we investigated efficacy a classification framework distinguish early (EMCI) from late (LMCI) by using features derived three frequency bands (full-band: 0.01-0.08 Hz; slow-4: 0.027-0.08 slow-5: 0.01-0.027 Hz) at Rest. Graphic theory was performed calculate and analyze relationship...
Corneal diseases present a significant challenge to global health. Given the uneven distribution of ophthalmic resources, development system facilitate remote diagnosis corneal is particularly crucial. In this study, we developed an artificial intelligence named Gancor, based on large-scale clinical dataset comprising 9669 anterior segment (AS) images and corresponding fluorescein staining (CFS) from Affiliated Eye Hospital Nanchang University, as well 967 pairs AS-CFS captured via...
Abstract The ability to perceive, understand, and react the feelings of others' pain is referred as empathy for which composed two components, affective‐perceptual cognitive‐evaluative empathy. Recent reviews on neural mechanisms empathetic showed anterior insula (AI) cortex a core circuit However, little known about modulation brain anatomy empathic responses by trait measures (trait empathy). Thus, we investigated whether individual variation in personality associated with structure...
Recent studies have suggested that the right inferior frontal gyrus (rIFG) may be involved in pain-related empathy. To verify role of rIFG, we performed a functional magnetic resonance imaging (fMRI) experiment to replicate previous research and further designed noninvasive repetitive transcranial stimulation (rTMS) probe causal rIFG empathy processing. We assigned 74 volunteers (37 females) three groups. Group 1 (n = 26) task which participants were required perceive pain others (task pain:...
Obsessive-compulsive disorder (OCD) is a common neuropsychiatric characterized by intrusive thoughts (obsessions) and repetitive behaviors (compulsions), few studies have assessed the whole-brain functional connectivity architecture of OCD with electroencephalogram (EEG) during different resting states. Graph theory network-based statistics (NBS) were employed to examine neural synchronization (FC) based on phase-locking value (PLV) patients healthy controls (HCs) eyes-closed (EC) eyes-open...
Abstract While converging sources of evidence point to the possibility a large‐scale distributed network for semantic cognition, consensus regarding underlying subregions and their specific function in this has not been reached. In current study, we combined functional magnetic resonance imaging (fMRI) transcranial stimulation (TMS) methodology investigate neural basis cognition Mandarin Chinese. fMRI experiment, strong activations were observed left inferior frontal gyrus (IFG) middle...
Polycyclic aromatic hydrocarbons (PAHs) have become a major type of persistent organic pollutant (POPs) in the world. To well understand occurrence, spatial distribution and source apportionment 16 PAHs different media Beijing, comprehensive study was conducted based on 337 obtained subsequently selected samples four specific media, including soil, road dust, surface water atmosphere covering sampling time spanning from 2005 to 2014. Mean concentrations Σ16 soils (878.5 μg/kg) decreased...
The contents of working memory (WM) can affect the subsequent visual search performance, resulting in either beneficial or cost effects, when target is included spatially dissociated from memorized contents, respectively. right dorsolateral prefrontal cortex (rDLPFC) and posterior parietal (rPPC) have been suggested to be associated with congruence/incongruence effects content target. Thus, present study, we investigated role DLPFC PPC controlling interaction between WM attention during a...
Working memory (WM) training is a prevalent intervention for multiple cognitive deficits, however, the transfer effects to other tasks from gains in WM induced by different techniques still remains controversial. Therefore, current study recruited three groups of young adults investigate transference, with N-back group (NBG) (n = 50) on dual n-back task, Memory Palace (MPG) method loci, and blank control (BCG) 48) receiving no training. Our results showed that both separately improved...
The experience in virtual reality (VR) is unique, that observers are a real-world location while browsing through scene. Previous studies have investigated the effect of environment on distance estimation. However, it unclear how influences estimation VR. Here, we measured using bisection (Experiment 1) and blind-walking (Experiments 2 3) method. Participants performed judgments VR, which rendered either indoor or outdoor scenes. Experiments were also carried out locations. In experiment,...
Parkinson's disease is a neurodegenerative disorder with an inflammatory response as the core pathogenic mechanism. Previous human genetics findings support view that loss of TREM2 function will aggravate neurodegeneration, and one most highly expressed receptors in microglia. However, role mechanism PD not clear. In our study, it was found both
Abstract Background Cue exposure therapy is used to treat alcohol dependence. However, its effectiveness controversial due the limitations of clinical treatment setting. Virtual reality technology may improve therapeutic effect. The aim this study explore whether virtual reality-based cue can reduce psychological craving and physiological responses patients with Methods Forty-four male alcohol-dependent were recruited divided into group (n = 23) control 21) according a random number table....
Noninvasive brain stimulation provides a promising approach for the treatment of neuropsychiatric conditions. Despite increasing research on facilitatory effects this kind cognitive processes, majority studies have used standard approaches such as transcranial direct current and conventional repetitive magnetic (rTMS) which seem to be limited in robustness duration transient effects. However, recent specialized type rTMS, theta-burst (TBS), patterned mimic natural cross-frequency coupling...
Every individual experiences negative emotions, such as fear and anger, significantly influencing how external information is perceived processed. With the gradual rise in brain-behavior relationship studies, analyses investigating differences emotion processing a more objective measure response time (RT) remain unexplored. This study aims to address this gap by establishing that speed of facial discrimination can be predicted from whole-brain functional connectivity when participants were...
Temporal attention is the concentration of perceptual resources at a specific point in time, which can help individuals get prepared to improve their behavioral performance, whereas neural mechanism temporal yet be well understood. In this study, measurement, transcranial direct current stimulation (tDCS), and electroencephalography (EEG) were combined explore effects task performance whole-brain functional connectivities (FCs) during with different time intervals after applying anodal sham...