A5101475204- Animal Nutrition and Physiology
- Effects of Environmental Stressors on Livestock
- Animal Behavior and Welfare Studies
- Meat and Animal Product Quality
- Gut microbiota and health
- Clostridium difficile and Clostridium perfringens research
- Livestock and Poultry Management
- Biochemical Analysis and Sensing Techniques
- Biosensors and Analytical Detection
- Surgical Sutures and Adhesives
- Nutritional Studies and Diet
- Immune Cell Function and Interaction
- Probiotics and Fermented Foods
- Wound Healing and Treatments
- Neuroendocrine regulation and behavior
- Insect and Pesticide Research
- Phytoestrogen effects and research
- Phagocytosis and Immune Regulation
- Ovarian function and disorders
- Energy, Environment, Economic Growth
- Additive Manufacturing Materials and Processes
- Mycobacterium research and diagnosis
- GDF15 and Related Biomarkers
- Parathyroid Disorders and Treatments
- Nanoplatforms for cancer theranostics
Purdue University West Lafayette
2014-2024
Nanchang University
2024
King's College London
2023-2024
Aerospace Center Hospital
2024
The First Affiliated Hospital, Sun Yat-sen University
2021-2024
Sun Yat-sen University
2021-2024
Zhejiang University
2024
Soochow University
2021-2024
State Key Laboratory of Food Science and Technology
2024
Hangzhou City University
2023-2024
Probiotics reduce stress-related inflammation and abnormal behaviors in humans rodents via regulation of the microbiota-gut-brain axis. The objective this study was to determine if probiotic, Bacillus subtilis, has similar functions broiler chickens under heat stress (HS). Two hundred forty 1-d-old chicks were assigned 48 pens with 4 treatments: Thermoneutral (TN)-RD (regular diet), TN-PD (the regular diet mixed 1 × 106 CFU/g feed probiotic), HS-RD HS-PD. Probiotic (Sporulin) fed from day 1;...
Macrophages play a crucial role in immune activation and provide great value the prognosis of cancer treatments. Current strategies for prognostic evaluation macrophages mainly target specific biomarkers to reveal number distribution tumors, whereas phenotypic change M1 M2 situ is less understood. Here, we designed an ultrasmall superparamagnetic iron oxide nanoparticle-based molecular imaging nanoprobe quantify repolarization by magnetic resonance (MRI) using redox-active nitric (NO) as...
Dietary (poly)phenols have received great interest due to their potential role in the prevention and management of non-communicable diseases. In recent years, a high inter-individual variability biological response has been demonstrated, which could be related (poly)phenol gut microbial metabolism existing within individuals. An interplay between microbiota exists, with being metabolised by metabolites modulating diversity composition. A number metabolising phenotypes or metabotypes...
This study evaluated the effects of dietary probiotic supplement and postmortem storage on meat quality chicken breast during retail display. A total 35 birds were randomly obtained from 3 feeding groups (control without supplement, 250 ppm Sporulin, 500 PoultryStar). The had no influence feed conversion ratio body weight gain, as well at 29 44 d (P > 0.05). After slaughter, each side muscles (M. Pectoralis major) was assigned to either one or 5 storage. Probiotic rate pH decline initial 6 h...
Tumor radiofrequency ablation (RFA) is a local and minimally invasive application using high temperature to induce coagulative necrosis of tumor, which has been commonly used in clinic. Although the tumor fragments generated by RFA can activate host's immune system, it may be insufficient inhibit cancer recurrence due many factors such as inefficient antigen presentation dendritic cells (DCs). In this research, convenient administration strategy blocking rho-associated kinases (ROCK) applied...
The aim of this study was to examine if synbiotics can function as alternatives antibiotics in broiler production under heat stress (HS). Day-old chicks (528 birds) were randomly placed floor pens within 2 identical temperature-controlled rooms (11 birds/pen and 24 pens/room). each room evenly divided among 3 treatments (n = 8): basal diet (CON), the mixed with 50 ppm bacitracin methylene disalicylate (BMD) or a synbiotic (50 PoultryStar meUS, SYN). From d 15, thermoneutral (TN) conditions...
Background: Dietary (poly)phenol consumption is inversely associated with cardiovascular disease (CVD) risk in epidemiological studies, but little known about the role of gut microbiome this relationship. Methods: In 200 healthy females, aged 62.0 ± 10.0 years, from TwinsUK cohort, 114 individual metabolites were measured spot urine using ultra-high-performance liquid chromatography–mass spectrometry. The associations between metabolites, (alpha diversity and genera), scores investigated...
Ammonia (NH3) is a potential health hazard to both humans and animals, causing local systemic low-grade inflammation based on its levels exposure durations. The objective of this study was examine the effects 45 wk 30 ppm NH3 concentrations acute-phase proteins, immunoglobulins, cytokines in laying hens. At 18 age, group Hy-Line W-36 hens randomly assigned 4-hen cages. These cages were evenly divided between 2 environmentally controlled chambers. 25 one chamber maintained continuously with...
A series of hydrogels containing guanidine-based polymers using a poloxamer as the matrix were prepared to provide novel wound dressings with antibacterial and repairing-promotion properties for skin wounds. Herein, we developed hydrogels, cationic polymer polyhexamethylene guanidine hydrochloride (PHMG) aqueous solution (12%, w/w) simplified PHMGP, chitosan (CS)-cross-linked PHMG (referred PHMC) PHMCP, hyaluronic acid (HA)-modified PHMH) PHMHP, enhancing full-thickness healing. The...
Recent studies have revealed that fecal microbiota transplantation exerts beneficial effects on modulating stress-related inflammation and gastrointestinal health of the host. The aim this study was to examine if cecal (CMT) presents similar efficiency in improving status egg-laying strain chickens. Chicken lines 63 72 divergently selected for resistance or susceptibility Marek's disease were used as CMT donors. Eighty-four d-old male recipient chicks (a commercial DeKalb XL layer strain)...
The gut microbiota plays an important role in regulating brain function, influencing psychological and emotional stability. correlations between conspecific aggression, microbiota, physiological homeostasis were further studied inbred laying chicken lines, 63 72, which diversely selected for Marek’s disease, they also behave differently aggression. Ten sixty-week-old hens from each line sampled blood, brain, cecal content. Neurotransmitters, cytokines, corticosterone, heterophil/lymphocyte...
High ambient temperature (heat stress, HS) is one of the critical environmental factors causing gut microbiota dysbiosis and increasing permeability, consequently inciting neuroinflammation in humans various animals including chickens. The aim this study was to examine if a probiotic, Bacillus subtilis, can reduce heat-stressed broiler Two hundred forty 1-d-old chicks were randomly assigned 48 pens among 4 treatments 2 identical, thermal-controlled rooms (n = 12): Thermoneutral (TN)-regular...
Abstract Background Accumulating evidence from human trials and rodent studies has indicated that modulation of gut microbiota affects host physiological homeostasis behavioral characteristics. Similarly, alterations in could be a feasible strategy for reducing aggressive behavior improving health chickens. The study was conducted to determine the effects early-life cecal transplantation (CMT) on microbial composition, brain serotonergic activity, recipient Methods Chicken lines 6 3 7 2 with...
Injurious behaviors (i.e., aggressive pecking, feather and cannibalism) in laying hens are a critical issue facing the egg industry due to increased social stress related health welfare issues as well economic losses. In humans, stress-induced dysbiosis increases gut permeability, releasing various neuroactive factors, causing neuroinflammation neuropsychiatric disorders via microbiota-gut-brain axis, consequently increasing frequency intensity of aggression violent behaviors. Restoration...
The incidence of thyroid cancer in China has rapidly increased recent decades. As the genetic profiles vary dramatically between different geographical regions, a comprehensive landscape Chinese population is urgently needed. We retrospectively included patients from three medical centers February 2015 and August 2020. To dissect genomic profiling these patients, we performed targeted next-generation sequencing on their tumor tissues using 1,021-gene panel. A total 458 with were enrolled,...
Cold temperature is a common environmental stressor that induces pathophysiological stress in birds with profound economic losses. Current methods used for preventing cold stress, such as reducing ventilation and using gas heaters, are facing challenges due to poor indoor air quality deleterious effects on bird caretaker health. The aim of this study was examine if the novel designed warmed perch system, thermal device, can reduce stress-associated adverse laying hens. Seventy-two...