A5060093091- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cardiac, Anesthesia and Surgical Outcomes
- Diabetes Treatment and Management
- Diabetes Management and Research
- Nausea and vomiting management
- Enhanced Recovery After Surgery
- Cardiac and Coronary Surgery Techniques
- Metabolism, Diabetes, and Cancer
- Anesthesia and Pain Management
- Heart Rate Variability and Autonomic Control
- Sleep and related disorders
- Inflammatory mediators and NSAID effects
- Sleep and Wakefulness Research
- Clinical practice guidelines implementation
- Congenital gastrointestinal and neural anomalies
- Hemodynamic Monitoring and Therapy
- Intensive Care Unit Cognitive Disorders
- Esophageal and GI Pathology
- Obesity, Physical Activity, Diet
- Blood Pressure and Hypertension Studies
- Gastrointestinal disorders and treatments
- Gout, Hyperuricemia, Uric Acid
- Healthcare cost, quality, practices
- Sodium Intake and Health
- Polyamine Metabolism and Applications
Amsterdam University Medical Centers
2018-2025
University of Amsterdam
2015-2025
Amsterdam UMC Location University of Amsterdam
2012-2018
UCB Pharma (Belgium)
1978-1983
Association Pharmaceutique Belge
1983
Summary In this open‐label multicentre randomised controlled trial, we investigated three peri‐operative treatment strategies to lower glucose and reduce the need for rescue insulin in patients aged 18–75 years with type‐2 diabetes mellitus undergoing non‐cardiac surgery. Patients were randomly allocated using a web‐based randomisation program premedication liraglutide (liraglutide group), glucose–insulin–potassium infusion (insulin group) or bolus regimen targeting < 8.0 mmol.l −1 . The...
Abstract In patients born with anorectal malformations (ARM), additional congenital heart defects (CHD) can occur. We aimed to provide an overview on disease and treatment details of CHD identified in ARM, from a unique large cohort very rare disease. performed retrospective single-center study between January 2000 July 2023. All consecutive ARM were included. Outcomes the number CHD, screening percentage diagnosed over 3 time periods (2000–2006, 2007–2014, 2015–2023). used uni-...
Abstract Objective To assess the prevalence of high blood pressure (BP) and association overweight obesity with BP among adolescents in Aracaju, Brazil. Design Cross-sectional study. The main outcome measure was proportion (sex-, age- height-specific ≥95th percentile). predictor variables were defined according to criteria International Obesity Task Force. Other covariates included age, socio-economic status leisure-time physical activity. Setting Brazil, capital city Sergipe State,...
Background. Asthma has been linked to cardiovascular diseases (CVDs) and related risk factors such as hypertension in adults. It is unclear whether the relationship between asthma found among adults also observed adolescents. Hence, authors examined its association with prehypertension adolescents Aracaju, Brazil. Methods. Data on blood pressure were collected 1002 age 12 17 years old 15 public schools, 5 municipal 10 private schools. data ascertained by International Study of Allergies...
Historically, metformin was withheld before surgery for fear of metformin‐associated lactic acidosis. Currently, however, this risk is deemed to be low and guidelines have moved towards the continuation metformin. We hypothesized that continuing peri‐operatively would lower postoperative serum glucose level without an effect on plasma lactate levels. performed a single‐blind multicentre randomized controlled trial in people with type 2 diabetes mellitus scheduled non‐cardiac continued (MF+...
Abstract Although sleep is essential for (recovery of) health, it adversely affected by hospitalization, due to disease discomfort, environmental noise, and care routines, causing reduced increased disturbances. This study evaluates factors affecting quality quantity in hospitalized children compares inpatient with at home. Using an observational, prospective design, we assessed aged 1–12 years, admitted a tertiary center, compared this home 6–8 weeks after discharge. We measured total time...
Background: The glycemic response and its relation to postoperative complications following gynecologic laparotomies is unknown, although these surgeries carry a substantial risk for morbidity. Therefore, our objective was assess the prevalence of perioperative hyperglycemia glucose variability in women undergoing laparotomy. Methods: In this prospective cohort study, capillary measured every hour during period. primary outcome measures were proportion patients with (glucose >180 mg d l...
Surgery and anesthesia pose a threat to patients with very long-chain acyl-CoA dehydrogenase deficiency (VLCADD), because prolonged fasting, stress, pain are known risk factors for the induction of metabolic derangement. The optimal perioperative management in these is unknown use volatile agents dissolved fatty acids has been related postoperative complications. However, occurrence derangement multifactorial depends, amongst others, on severity mutation residual enzyme activity. Current...
Diabetes mellitus (DM) is associated with poor outcome after surgery. The prevalence of DM in hospitalised patients up to 40%, meaning that the anaesthesiologist will encounter a patient operating room on daily basis. Despite an abundance published glucose lowering protocols and known negative outcomes perioperative hyperglycaemia DM, there no evidence regarding optimal intraoperative treatment. In addition, protocol adherence usually low targets are not simply met. Recently, incretins have...
Most perioperative diabetes mellitus (DM) guidelines do not distinguish between patients with type 1 (DM1) and 2 (DM2). We hypothesised that similar treatment of DM1 DM2 leads to differences in their glucose control.We performed a retrospective cross-sectional study, all DM undergoing surgery May 2013 November 2015 Dutch university hospital. compared patients, treated according the same protocol. Our primary outcome was incidence hyperglycaemia (glucose ≥10 mmol/L). Secondary outcomes were...