Md. Mahfuzur Rahman

ORCID: 0000-0002-2917-8991
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Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Viral gastroenteritis research and epidemiology
  • Virology and Viral Diseases
  • Neurosurgical Procedures and Complications
  • Diabetes Management and Research
  • vaccines and immunoinformatics approaches
  • Animal Virus Infections Studies
  • COVID-19 epidemiological studies
  • Viral Infections and Vectors
  • Diabetes Treatment and Management
  • Hepatitis Viruses Studies and Epidemiology
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Bone and Joint Diseases
  • Rabies epidemiology and control
  • Diabetes and associated disorders
  • Neonatal Respiratory Health Research
  • SARS-CoV-2 detection and testing
  • Renin-Angiotensin System Studies
  • Healthcare Systems and Public Health
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Atherosclerosis and Cardiovascular Diseases
  • Mechanical Circulatory Support Devices

International Centre for Diarrhoeal Disease Research
2012-2024

Noakhali Science and Technology University
2024

National Institute of Neurosciences & Hospital
2017-2021

Kagoshima University Hospital
2021

Calcutta National Medical College and Hospital
2019

Novo Nordisk (United Kingdom)
2013

Kagoshima University
2012

University of Dhaka
2012

BRAC University
1985

Abstract The protection against emerging SARS-CoV-2 variants by pre-existing antibodies elicited due to the current vaccination or natural infection is a global concern. We aimed investigate rate of and its clinical features among infection-naïve, infected, vaccinated, post-infection-vaccinated individuals. A cohort was designed icddr,b staff registered for COVID-19 testing real-time reverse transcriptase-polymerase chain reaction (rRT-PCR). Reinfection cases were confirmed whole-genome...

10.1038/s41598-022-05325-5 article EN cc-by Scientific Reports 2022-01-26

All authors have no conflicts of interest to disclose. data and materials used in this work were publicly available. Sequences published GISAID (www.gisaid.org) database under the accession numbers EPI_ISL_1715160, EPI_ISL_1715161, EPI_ISL_1715163, EPI_ISL_1715164, EPI_ISL_1715165, EPI_ISL_1715166, EPI_ISL_1715168, EPI_ISL_1715169, EPI_ISL_1715170, EPI_ISL_1717025, EPI_ISL_1793786, EPI_ISL_1793787, EPI_ISL_1793789, EPI_ISL_1793791, EPI_ISL_1828781, EPI_ISL_890237, EPI_ISL_2233364,...

10.1111/tbed.14203 article EN Transboundary and Emerging Diseases 2021-06-25

BackgroundNipah virus (NiV) infection, often fatal in humans, is primarily transmitted Bangladesh through the consumption of date palm sap contaminated by Pteropus bats. Person-to-person transmission also common and increases concern large outbreaks. This study aimed to characterize molecular epidemiology, phylogenetic relationship, evolution nucleocapsid gene (N gene) NiV.MethodsWe conducted detection, genetic characterization, Bayesian time-scale analyses NiV using pooled Pteropid bat...

10.1016/j.ijid.2020.10.041 article EN cc-by-nc-nd International Journal of Infectious Diseases 2020-10-28

The coding-complete genome sequence of a coronavirus strain, SARS-CoV-2/human/BGD/G039392/2021, obtained from symptomatic male patient with disease 2019 (COVID-19) in Dhaka, Bangladesh, is reported. strain G039392 99.9% identical to the UK variant B.1.1.7.

10.1128/mra.00100-21 article EN Microbiology Resource Announcements 2021-02-24

Nipah virus (NiV) is an emerging zoonotic causing outbreaks of encephalitis and respiratory illnesses in humans, with high mortality. NiV considered endemic Bangladesh Southeast Asia. There are no licensed vaccines against NiV. This study aimed at predicting a dual-antigen multi-epitope subunit chimeric vaccine surface-glycoproteins G F Targeted proteins were subjected to immunoinformatics analyses predict antigenic B-cell T-cell epitopes. The proposed designs implemented based on the...

10.1007/s10989-022-10431-z article EN cc-by International Journal of Peptide Research and Therapeutics 2022-06-23

To date, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected over 80 million people globally. We report a case series of five clinically and laboratory confirmed COVID-19 patients from Bangladesh who suffered second episode illness after 70 symptom-free days. The International Centre for Diarrhoeal Disease Research, (icddr,b), is leading public health research institution in South Asia. icddr, b staff were actively tested, treated followed-up by an experienced team...

10.3390/tropicalmed6020041 article EN cc-by Tropical Medicine and Infectious Disease 2021-03-31

The rapid and early detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is key to control the current Coronavirus disease 2019 (COVID-19) pandemic. present study was conducted clinically evaluate a diagnostic test (RDT) kit, Standard Q COVID-19 Ag Test (SD Biosensor®, Republic Korea), with reference standard real-time RT-PCR for cases in Bangladesh. Nasopharyngeal swabs were taken from 900 suspected patients. Among them, 34.11% (n = 307) diagnosed as by...

10.1016/j.heliyon.2021.e08455 article EN cc-by-nc-nd Heliyon 2021-11-01

Norovirus is a major cause of endemic acute gastroenteritis (AGE) worldwide. We described the epidemiology, risk factors, and genotypic distribution noroviruses among hospitalized patients all ages in Bangladesh.From March 2018 to October 2021, 1250 AGE case controls (age, sex, season, site matched) were enrolled at 10 hospitals. Demographic clinical information was collected; real-time reverse-transcriptase polymerase chain reaction (RT-PCR) used test stool specimens, positive samples...

10.1093/infdis/jiad274 article EN cc-by-nc-nd The Journal of Infectious Diseases 2023-07-28

A simple, sensitive and accurate spectrophotometric method has been developed for the deterrmination of Olmesartan Medoxomil in raw material tablets. The ?max was found to be 256 nm. linear dynamic response concentration range 4-14 ?g/mL coefficient correlation 0.9993. %RSD value below 2.0 intraday interday precision indicated that highly precise. LOD LOQ were 0.105 0.3045 respectively which revealed sensitive. percentage recovery higher than 100 %, indicating accuracy absence interference...

10.3329/ijpls.v1i3.12980 article EN International Journal of Pharmaceutical and Life Sciences 2012-12-15

Background: Unstable angina (UA) and Non-ST elevation myocardial infarction (NSTEMI) impose significant health economic burden on Bangladesh. Anticoagulants are recommended as standard therapy by various clinical practice guidelines. Recent studies have shown fondaparinux's superiority over enoxaparin in patients with UA & NSTEMI, especially bleeding reduction. The description of this finding has not yet been documented any study from This aimed to evaluate the efficacy safety...

10.3329/bhj.v39i1.70709 article EN Bangladesh Heart Journal 2024-01-04

Md. Maharub Hossain Fahim, Walid Hassan, Afia Afsin, Mahfuzur Rahman, Tanvir Sang Jin Lim, Yeonsu Oh, Yung Chul Park, Faruquee and Mafizur Rahman. J Ecol Environ 2024;48:. https://doi.org/10.5141/jee.24.003

10.5141/jee.24.003 article EN Journal of Ecology and Environment 2024-05-03

Nipah virus (NiV) is a lethal bat-borne zoonotic that causes mild to acute respiratory distress and neurological manifestations in humans with high mortality rate. NiV transmission occurs via consumption of bat-contaminated fruit date palm sap (DPS), or through direct contact infected individuals livestock. Since outbreaks were first reported pigs from Malaysia Singapore, non-neutralizing antibodies against attachment Glycoprotein (G) have also been detected few domestic mammals. infection...

10.1016/j.meegid.2023.105516 article EN cc-by-nc-nd Infection Genetics and Evolution 2023-11-03

We report a coding-complete genome sequence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strain SARS-CoV-2/BGD/GC001, isolated from Bangladeshi patient with symptoms. Phylogenetic analysis assigned this to lineage B.1.1.7, which presented total 36 mutations in spike and other genomic regions compared Wuhan Hu-1 (GenBank accession number NC_045512.2).

10.1128/mra.00345-21 article EN Microbiology Resource Announcements 2021-05-27

Background/Aim: The reproducibility of athero – sclerotic lesions was evaluated after the production cloned-microminipigs and their offspring. Materials Methods: Cloned-microminipig-parents were produced by microminipigsomatic cell nuclei. These parents crossbred delivered males (F1-offspring) divided into two groups: normal chow diet (NcD)-fed high-fat/high-cholesterol (HcD)-fed groups. One F1-offsprings subjected to cloning, (F1-clones) fed with HcD. After 8 weeks, all animals necropsied...

10.21873/invivo.12471 article EN In Vivo 2021-01-01

The authors have investigated the structural phase stability of certain brass-type alloys in terms a third-order pseudopotential theory. contributions to free energy are found play important roles predicting crystal structures these alloys.

10.1088/0305-4608/15/2/020 article EN Journal of Physics F Metal Physics 1985-02-01

Objective: To present results from the Bangladesh cohort of A1chieve study receiving insulin detemir (Levemir) ± oral anti diabetic drugs. Methods: Out 1093 patients recruited 49 sites in Bangladesh, 370 were initiated on (Levemir).Study visits defined as baseline, interim (around 12 weeks baseline) and final 24 visit. Results: Glycaemic control was poor all groups at baseline. In entire weeks, significant reductions baseline observed mean HbA1c (from 10.0 % to 7.2%, p<0.001), FPG 10.5...

10.3329/birdem.v3i1.17121 article EN BIRDEM Medical Journal 2013-11-24

Background: The emergence of novel variants has been a great deal international concern since the recently published data suggest that previous infections with SARS-CoV-2 may not protect an individual from new variants. We report patient had two distinct episodes COVID-19 different SARS-CoV-2. Methods: nasopharyngeal samples collected were subjected to whole-genome sequencing and comparative genome analysis. Results: first infection presented mild symptoms, while second severe outcomes which...

10.3389/fmicb.2021.792514 article EN cc-by Frontiers in Microbiology 2021-12-09
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