A5038507722- Medicinal Plants and Bioactive Compounds
- Theatre and Performance Studies
- Philippine History and Culture
- Biochemical Acid Research Studies
- Chinese history and philosophy
- Irish and British Studies
- Sulfur Compounds in Biology
- Covalent Organic Framework Applications
- Apelin-related biomedical research
- Hong Kong and Taiwan Politics
- Advanced Polymer Synthesis and Characterization
- Asian Culture and Media Studies
- Parkinson's Disease Mechanisms and Treatments
- Dendrimers and Hyperbranched Polymers
- Scottish History and National Identity
- MXene and MAX Phase Materials
- Aortic aneurysm repair treatments
- Molecular Sensors and Ion Detection
- Joseph Conrad and Literature
- Traditional and Medicinal Uses of Annonaceae
- Vietnamese History and Culture Studies
- Cardiac Health and Mental Health
- Infectious Aortic and Vascular Conditions
- Stroke Rehabilitation and Recovery
- Autophagy in Disease and Therapy
Wenzhou Medical University
2021-2024
First Affiliated Hospital of Wenzhou Medical University
2021-2024
University of Chinese Academy of Sciences
2018-2024
Nankai University
2022
Henan University of Science and Technology
2022
Shanghai Institute of Organic Chemistry
2017-2021
Chinese Academy of Sciences
2017-2021
ShanghaiTech University
2017-2021
Nanjing University of Finance and Economics
2021
Air Force Medical University
2017-2019
Cerebral ischemic stroke (IS) is still a difficult problem to be solved; energy metabolism failure one of the main factors causing mitochondrion dysfunction and oxidation stress damage within pathogenesis cerebral ischemia, which produces considerable reactive oxygen species (ROS) opens blood-brain barrier. Dichloroacetic acid (DCA) can inhibit pyruvate dehydrogenase kinase (PDK). Moreover, DCA has been indicated with capability increasing mitochondrial uptake promoting glucose in course...
Parkinson's disease (PD) is a common neurodegenerative characterized by the degeneration of nigrostriatal dopaminergic (DA) neurons. Our previous studies have suggested that salidroside (Sal) might play neuroprotective effects against PD preserving mitochondrial Complex I activity. However, exact mechanism effect Sal remains unclear. Growing evidence indicates PINK1/Parkin-mediated mitophagy involved in development PD. In this study, we investigated whether exerts modulating mitophagy....
This review has summarized the recent advances about rules and strategies in preparation applications of crystalline elemental phosphorus several highly concerned sustainable processes.
This article presents a new type of well-defined ferrocene-containing homopolymer obtained from RAFT polymerization, showing pH/CO<sub>2</sub> and redox responsiveness.
Parkinson's disease (PD) is characterized by the loss of dopaminergic (DA) neurons in substantia nigra pars compacta (SNc) and presence Lewy bodies (LBs) surviving SNc neurons. LBs formation caused accumulation α-synuclein (α-syn) or phosphorylated α-syn at serine-129 (pSer129-α-syn), which implicated pathological progression PD. Salidroside (Sal), main active ingredient root Rhodiola rosea L., has been reported to have potent neuroprotective properties our previous investigations. Here, we...
Biological thiols with similar structures, such as glutathione (GSH), N-acetyl-l-cysteine (NAC), homocysteine (Hcy) and cysteine (Cys), play important roles in human physiology are associated different diseases. Thus, the discrimination of these is a great necessity for various biochemical investigations diagnosis related Herein, we present new dual-signaling probe consisting typical aggregation induced emission fluorogen tetraphenylethylene group 2,4-dinitrobenzenesulfonyl moiety. The can...
The pathogenic mechanism of Parkinson’s disease (PD) remains to be elucidated; however, mitochondrial dysfunction at the level complex I and oxidative stress is suggestively involved in development PD. In our previous work, salidroside (Sal), an active component extracted from medicinal plant Rhodiola rosea L., might protect dopaminergic (DA) neurons through modulating ROS–NO-related pathway. However, Sal-induced neuroprotective effects against PD poorly understood. Therefore, we further...
Mitochondrial complex I damage and oxidative stress play critical roles in the degeneration of dopaminergic (DA) neurons during progression Parkinson's disease (PD). Our previous study showed that NADH dehydrogenase 6 (ND6), exclusively regulated by mitochondrial myocyte enhancer factor 2D (MEF2D), was for assembly. Recently, we found Salidroside (Sal), isolated from Rhodiola rosea L., protected DA regulating stress-related pathways. Here, investigated whether MEF2D-ND6 pathway involved...
Parkinson's disease (PD) is the second most common neurodegenerative disorder. We have found that salidroside (Sal) exhibited neuroprotective effects against MPP+ toxicity. However, molecular mechanism not fully understood. In this study, we Sal significantly prevented MPP+-induced decrease of mRNA and protein expression Nrf2, GCLc, SOD1, SOD2 in SH-SY5Y cells. Moreover, silencing Nrf2 inhibited Sal-induced increase SOD2. But silence did impact Sal-exhibited on DJ-1 expression. Silencing...
A PEG<sub>45</sub>-<italic>b</italic>-PVPOP<sub>14</sub> diblock copolymer with pendant levulinate-protected phenol groups exhibited a highly specific response toward sulfites.
This article reports platform to prepare polymeric nano-carriers capable of releasing SO<sub>2</sub> and hydrophobic payloads upon triggering by mercapto-containing species.
Heterogeneous enterprise agglomeration is an important perspective in understanding urban exports and reshaping the new advantages of openness. This paper considers data from China's industrial enterprises municipality-level panel 192 cities to systematically examine enterprises' heterogeneity, patterns, exports. The results reveal that: (1) heterogeneity productivity exhibits a significant promotional effect on central northeastern regions, but not its western regions; (2) specialized...
Abstract Objective: Cabrol fistulas are often used as a bailout procedure in cases of reoperation and severe calcifications complex aneurysm surgery. However, the justification for using aortic dissection has been controversial. This study retrospectively evaluated clinical outcomes prophylactic use fistulas. Methods: The design this was retrospective study. We queried 414 patients with aneurysms or type A who underwent emergency selective surgery at our center from January 2015 to December...
Driven by the imperatives of a changing society and pressures new technology, China's theatre is undergoing rapid transformation. The work two leading Shanghai actors, Shang Changrong Shi Yihong, reveals how jingju (Beijing Opera) navigates traditional conventions emerging market challenges, negotiating future for art form.
Today's modern theatre in Beijing shows new talents and direc—tionsas well as problems that are part of the uncertainties Chi-nese society—in what may be most intriguing transitional period Chinese history.