A5086702269- Acupuncture Treatment Research Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Pain Mechanisms and Treatments
- Anesthesia and Neurotoxicity Research
- Nausea and vomiting management
- Pain Management and Placebo Effect
- Anesthesia and Pain Management
- Biochemical Acid Research Studies
- Immune Response and Inflammation
- Pediatric Pain Management Techniques
- Inflammasome and immune disorders
- Neuroscience and Neuropharmacology Research
- Vagus Nerve Stimulation Research
- Ferroptosis and cancer prognosis
- History of Medicine Studies
- RNA Research and Splicing
- Anesthesia and Sedative Agents
- Immune cells in cancer
- RNA modifications and cancer
- Intensive Care Unit Cognitive Disorders
- Fuel Cells and Related Materials
- Cardiac, Anesthesia and Surgical Outcomes
- Tryptophan and brain disorders
- interferon and immune responses
Wenzhou Medical University
2021-2025
First Affiliated Hospital of Wenzhou Medical University
2021-2025
Guilin Medical University
2014
Affiliated Hospital of Guilin Medical College
2013
Cerebral ischemic stroke (IS) is still a difficult problem to be solved; energy metabolism failure one of the main factors causing mitochondrion dysfunction and oxidation stress damage within pathogenesis cerebral ischemia, which produces considerable reactive oxygen species (ROS) opens blood-brain barrier. Dichloroacetic acid (DCA) can inhibit pyruvate dehydrogenase kinase (PDK). Moreover, DCA has been indicated with capability increasing mitochondrial uptake promoting glucose in course...
Previous studies have demonstrated that cardiomyocyte apoptosis, ferroptosis, and inflammation participate in the progress of sepsis-induced cardiomyopathy (SIC). Although Islet cell autoantigen 69 (ICA69) is an imperative molecule could regulate immune response numerous illnesses, its function cardiovascular disease, particularly SIC, still elusive. We confirmed LPS significantly enhanced expression ICA69 wild-type (WT) mice, macrophages, cardiomyocytes. The knockout...
Acupuncture is a treatment for neuropathic pain, but its mechanism remains unclear. Previous studies showed that analgesia was induced in rats with pain when their spinal cord adenosine content increased after electroacupuncture (EA); however, the behind this electroacupuncture-induced increase has not been clarified.This study aimed to determine role ecto-5'-nucleotidase plays EA-induced pain.We performed at Zusanli acupoint on seventh day establishing rat model of through chronic...
This study is to investigate the effects of etomidate and propofol on memory possible involved mechanisms using immature rats. Forty-eight rats randomly received intraperitoneal injection 5 mg/kg ( n = 16), 50 16) or normal saline (control, 16). Three hours after awakening, was assessed by Y-maze test 10 in each drug group. Gamma-aminobutyric acid (GABA) content hippocampal tissue measured six Etomidate group had more total reaction time (TRT) compared with control p < 0.05). No other...
Objective To investigate and compare the effects of etomidate or propofol on spatial cognitive, exploring, learning memory abilities hippocampus tissue in rapid development period rats. Methods Thirty-nine SD rats with an age from 17 to 18 days were randomly divided into group C(10 ml/kg normal saline), E(5 mg/kg etomidate), P(50 propofol)(n=13). They all single injected intraperitoneally.The tests cognitive function performed Open Field Test(OFT), Hole Board Test Y-maze at 3 hours...
Abstract Stroke is one of the most important diseases that seriously threaten health and public elderly patients.NSUN2 refers to predominant methyltransferase for RNA m5C methylation, contributing increased stability, translocation translation, playing an role in physiopathology. However, there insignificant progress on biological functions mechanisms NSUN2 cerebral ischemia-reperfusion injury. Here, C57BL/6 mice were employed establish a middle artery injury model (MCAO) found significantly...