A5032281205- Effects and risks of endocrine disrupting chemicals
- Analytical Chemistry and Chromatography
- Computational Drug Discovery Methods
- Toxic Organic Pollutants Impact
- Microplastics and Plastic Pollution
- Pharmaceutical and Antibiotic Environmental Impacts
- Lipid Membrane Structure and Behavior
- Drug Transport and Resistance Mechanisms
- Metabolomics and Mass Spectrometry Studies
- Advanced Chemical Sensor Technologies
- thermodynamics and calorimetric analyses
- Ionic liquids properties and applications
- Carcinogens and Genotoxicity Assessment
- Analytical Methods in Pharmaceuticals
- Protein Interaction Studies and Fluorescence Analysis
- Dialysis and Renal Disease Management
- Animal testing and alternatives
- Sphingolipid Metabolism and Signaling
- Neuroscience and Neuropharmacology Research
- Polymer Surface Interaction Studies
- Biomedical Research and Pathophysiology
- Catalytic Processes in Materials Science
- Chromatography in Natural Products
- Biochemical Analysis and Sensing Techniques
- Chemical and Physical Properties in Aqueous Solutions
Edinburgh Napier University
2020-2024
University of Messina
2024
University of Naples Federico II
2014-2022
Istituto Nazionale Biostrutture e Biosistemi
2018-2021
Ghent University
2017-2020
University of Helsinki
2017
The concentration levels of thirteen organic pollutants and selected heavy metals were investigated in 40 plastics bottled tap water samples. Some the contaminants have an ascertained or suspected endocrine disrupting activity, such as Bisphenol A (BPA) its analogs, Bis 2-ethylhexyl phthalate (DEHP), which are used by industries plasticizers. most frequently detected AF (BPAF) (detection frequency (DF) = 67.5%, mean 387.21 ng L-1), DEHP (DF 62.5%, 46.19 µg L-1) BPA 60.0%, 458.57 with higher...
A simple and sensitive validated analytical method based on liquid chromatography coupled to tandem fluorescence (FD) ultraviolet (UV) spectrophotometry was applied monitor the presence of bisphenol S in plastic baby bottles marketed Italy. The limits detection (LOD) were 3.75 ng mL−1 80.00 mL−1, those quantification (LOQ) 12.51 260.00 for BPA (FD detection) BPS (UV detection), respectively. found only four samples, two samples undergone microwave heating bottle warmer either at 40°C or...
Owing to their unique properties and unlimited structural combinations, the ubiquitous use of ionic liquids (ILs) is steadily increasing. The objective present work shed light onto effects amidinium- phosphonium-based ILs on phospholipid vesicles using a nanoplasmonic sensing measurement technique. A new relatively simple method was developed for immobilization large unilamellar two different hydrophilic surfaces composed titanium dioxide silicon nitride nanolayers. Among pretreatment...
In the present work, 79 structurally unrelated analytes were taken into account and their chromatographic retention coefficients, measured by immobilized artificial membrane liquid chromatography (IAM-LC) micellar (MLC) employing sodium dodecyl sulfate (SDS) as surfactant, determined. Such indexes, along with topological physicochemical parameters calculated in silico, subsequently used for development of blood-brain barrier passage-predictive statistical models using partial least-squares...
Parabens (PBs) are used as preservatives to extend the shelf life of various foodstuffs, and pharmaceutical cosmetic preparations. In this work, membrane barrier passage potential a subset seven parabens, i.e., methyl-, ethyl-, propyl- isopropyl, butyl, isobutyl, benzyl paraben, along with their parent compound, p-hydroxy benzoic acid, were studied. Thus, Franz cell diffusion (FDC) method, biomimetic liquid chromatography (BLC), in silico prediction performed evaluate soundness both...
This study pioneers a comparison of the application biomimetic techniques, immobilised artificial membrane liquid chromatography (IAM LC) and liposome electrokinetic capillary (LEKC), for prediction pulmonary drug permeability. The absorption profiles 26 structurally unrelated drug-like molecules were evaluated using their IAM hydrophobicity index (CHI IAM) measured in LC, logarithm distribution constants (log K
The affinity indexes for phospholipids (log kW(IAM)) 42 compounds were measured by high performance liquid chromatography (HPLC) on two different phospholipid-based stationary phases (immobilized artificial membrane, IAM), i.e., IAM.PC.MG and IAM.PC.DD2. polar/electrostatic interaction forces between analytes membrane (Δlog calculated as the differences experimental values of log kW(IAM) those expected isolipophilic neutral having polar surface area (PSA) = 0. passage through a porcine brain...
Abstract A quick and inexpensive validated method, based on sample treatment by liquid–liquid microextraction followed liquid chromatography (LC) coupled with ultraviolet tandem fluorescence detection is proposed for the determination of 15 multiclass pollutants both in serum saliva, as a simple easy to draw matrix. The method was set up according European guidelines. compounds interest include some endocrine‐disrupting chemicals (i.e. bisphenol A, B, E, F, AF, diglycidyl ether, M,...