A5004143021- Effects and risks of endocrine disrupting chemicals
- Microplastics and Plastic Pollution
- Receptor Mechanisms and Signaling
- Toxic Organic Pollutants Impact
- Neuropeptides and Animal Physiology
- Chemical Synthesis and Analysis
- Synthesis and Biological Evaluation
- Phenothiazines and Benzothiazines Synthesis and Activities
- Pesticide Residue Analysis and Safety
- Protein Kinase Regulation and GTPase Signaling
- Marine Sponges and Natural Products
- RNA Interference and Gene Delivery
- Quinazolinone synthesis and applications
- Antioxidant Activity and Oxidative Stress
- Recycling and Waste Management Techniques
- Edible Oils Quality and Analysis
- Pharmacological Receptor Mechanisms and Effects
- Synthesis and Reactivity of Heterocycles
- Protein Structure and Dynamics
- Analytical chemistry methods development
- Synthetic Organic Chemistry Methods
- Phytochemicals and Antioxidant Activities
- Adenosine and Purinergic Signaling
- Antimicrobial Peptides and Activities
- Mass Spectrometry Techniques and Applications
University of Naples Federico II
2015-2024
Istituto Nazionale Biostrutture e Biosistemi
2013-2024
Federico II University Hospital
1998-2010
University of Salerno
1996-2007
University of Pisa
2000-2007
University of Florence
2007
University of Perugia
2006
Northwestern University
2000
Menarini Group (Italy)
2000
Consorzio Pisa Ricerche
2000
Residue levels of seven pesticides were analyzed in thirty-five samples Extra Virgin Olive Oil to assess the health risk consuming Italian oils correlated with presence these pesticides. An in-house analytical procedure was developed and validated, consisting a specific dispersive solid-phase extraction using QuEChERS technique qualitative-quantitative analysis liquid chromatography coupled tandem mass spectrometry. Thirty-four percent contaminated pesticide residues; concentration range...
Bisphenol A (BPA) and bisphenol B (BPB) concentrations were determined in peeled canned tomatoes of different brands bought Italian supermarkets. Tomato samples analyzed packaged cans coated with either epoxyphenolic lacquer or low BADGE enamel. solid phase extraction (SPE) was performed on C-18 Strata E cartridge followed by a step Florisil cartridge. Detection quantitation reversed high-performance liquid chromatography (RP-HPLC) method both UV fluorescence detection (FD). On the total 42...
D-galactose, a simple natural compound, has been investigated as powerful scaffold for drug delivery, diagnostics, and theranostics due to its distinctive properties interactions with specific cell receptors. In the field of galactose functions ligand selectively target cells expressing receptors, such hepatocytes, macrophages, cancer cells. The direct attachment main or drug-loaded nanoparticles liposomes enhances cellular uptake, thereby improving delivery intended Galactose also found be...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAmphitoxin, a New High Molecular Weight Antifeedant Pyridinium Salt from the Caribbean Sponge Amphimedon compressaStefania Albrizio, Patrizia Ciminiello, Ernesto Fattorusso, Silvana Magno, and Joseph R. PawlikCite this: J. Nat. Prod. 1995, 58, 5, 647–652Publication Date (Print):May 1, 1995Publication History Published online1 July 2004Published inissue 1 May...
A simple and sensitive validated analytical method based on liquid chromatography coupled to tandem fluorescence (FD) ultraviolet (UV) spectrophotometry was applied monitor the presence of bisphenol S in plastic baby bottles marketed Italy. The limits detection (LOD) were 3.75 ng mL−1 80.00 mL−1, those quantification (LOQ) 12.51 260.00 for BPA (FD detection) BPS (UV detection), respectively. found only four samples, two samples undergone microwave heating bottle warmer either at 40°C or...
Bisphenol A (BPA) is a synthetic compound utilized to manufacture plastics for Food Contact Materials (FCMs) or resins the inside of food containers. Since it was recognized as an Endocrine-Disrupting Chemical (EDC), its implications in pathologies, such cancer, obesity, diabetes, immune system alterations, and developmental mental disorders, have been widely documented. Diet considered main source exposure humans BPA. Consequently, continuous monitoring levels BPA foods necessary assess...
Microplastics, MPs, plastic fragments with a dimension lower than 5 mm, and microfibers, MFs, synthetic natural/artificial fibrous diameter 50 μm, are ubiquitous pollutants identified in different environmental compartments. In this work the occurrence of MPs MFs on honeybees, Apis mellifera, beehive products was evaluated, using Fourier transform infrared microspectroscopy, confirming that widely present as air contaminants all apiary's areas (high low urbanized areas) Southern Italy....
A method for the determination of dimethyl fumarate (DMF) in desiccant and antimould sachets, employed protecting consumer products from humidity mould, has been developed. The is based on a solid–liquid extraction followed by HPLC-UV analysis. was validated with respect to recovery, linearity, limits detection quantitation precision. recovery 98%. correlation coefficient value (r) equal 0.94. Both intra- inter-day precisions were studied at several concentration levels, being satisfactory...
The monitoring of the contamination levels bisphenol A (BPA) and its congeners B (BPB) F (BPF) in foodstuffs is a necessary process for assessment consumers' risk. After development validation method using Strata® C18-E cartridge cleanup with detection by liquid chromatography coupled to tandem mass spectrometry, forty-six samples fruit juices, sold on Italian markets, have been analysed assess concentration BPA, BPB BPF. BPF were not detected any samples, BPA was found 33 % samples....
Carbohydrates are one of the most abundant and important classes biomolecules. The variety in their structures makes them valuable carriers that can improve pharmaceutical phase, pharmacokinetics pharmacodynamics well-known drugs. D-galactose is a simple, naturally occurring monosaccharide sugar has been extensively studied for use as carrier proven to be this role. With aim validating galactose-prodrug approach, we have investigated galactosylated prodrugs ibuprofen, ketoprofen,...
The consumption of plant-based beverages as an alternative to cow's milk has recently gained vast attention worldwide. aim this work is monitor the intake Bisphenol A (BPA), B (BPB) and S (BPS) in Italian population through these foodstuffs. Specifically, development validation analytical procedure for quantitative determination analytes by liquid chromatography coupled tandem mass spectrometry was reported. Thirty-four samples (soya, coconut, almond, oats rice) popular brands marketed Italy...
The molecular mechanisms of interaction between G<sub>s</sub> and the A<sub>2A</sub> adenosine receptor were investigated using synthetic peptides corresponding to various segments Gα<sub>s</sub> carboxyl terminus. Synthetic tested for their ability modulate binding a selective radiolabeled agonist, [<sup>3</sup>H]2-[4-(2-carboxyethyl)phenylethylamino]-5′-<i>N</i>-ethylcarboxamidoadenosine ([<sup>3</sup>H]CGS21680), receptors in rat striatal membranes. stimulated specific both presence...