Liang-Yü Chen

ORCID: 0000-0002-2981-1945
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Silicon Carbide Semiconductor Technologies
  • Optical Imaging and Spectroscopy Techniques
  • Photoacoustic and Ultrasonic Imaging
  • Frailty in Older Adults
  • Semiconductor materials and devices
  • Nutrition and Health in Aging
  • Infrared Thermography in Medicine
  • Advanced ceramic materials synthesis
  • Gas Sensing Nanomaterials and Sensors
  • Electronic Packaging and Soldering Technologies
  • 3D IC and TSV technologies
  • Radiation Effects in Electronics
  • Advancements in Semiconductor Devices and Circuit Design
  • Acoustic Wave Resonator Technologies
  • Analytical Chemistry and Sensors
  • Dementia and Cognitive Impairment Research
  • Electromagnetic Compatibility and Noise Suppression
  • Electrical and Thermal Properties of Materials
  • Geriatric Care and Nursing Homes
  • Lipid Membrane Structure and Behavior
  • Antimicrobial Resistance in Staphylococcus
  • Digital Radiography and Breast Imaging
  • Non-Invasive Vital Sign Monitoring
  • Body Composition Measurement Techniques
  • Phytochemicals and Antioxidant Activities

Glenn Research Center
2007-2024

National Central University
2011-2024

Zhejiang University
2018-2024

Nanjing Drum Tower Hospital
2024

Southern Medical University
2021-2024

Macau University of Science and Technology
2024

Jiangsu University
2024

Nanjing University of Chinese Medicine
2024

Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine
2024

Ming Chuan University
2012-2023

The fact that wide bandgap semiconductors are capable of electronic functionality at much higher temperatures than silicon has partially fueled their development, particularly in the case SiC. It appears unlikely semiconductor devices will find use low-power transistor applications until ambient temperature exceeds approximately 300/spl deg/C, as commercially available and silicon-on-insulator technologies already satisfying requirements for digital analog VLSI this range. However practical...

10.1109/jproc.2002.1021571 article EN Proceedings of the IEEE 2002-06-01

A decline in physical and/or cognitive function is a common feature of aging, and frailty has been shown to be associated with impairment dementia. This study aimed evaluate the association between dynapenia, sarcopenia, among community-dwelling older people Taiwan. Data from I-Lan Longitudinal Aging Study (ILAS) were retrieved for study. Global was assessed by Mini-Mental State Examination (MMSE), whereas Chinese Version Verbal Learning Test, Boston Naming Fluency Taylor Complex Figure...

10.1089/rej.2015.1710 article EN Rejuvenation Research 2015-07-13

Short-term demonstrations of packaged 4H-SiC junction field-effect transistor (JFET) logic integrated circuits (ICs) at temperatures exceeding 800 °C in air are reported, including a 26-transistor 11-stage ring oscillator that functioned 961 ambient temperature believed unprecedented for electrical operation semiconductor IC. The expanded range should assist acceleration testing/qualification such ICs intended long-term use applications near 500 ambient, and perhaps spawn new applications....

10.1109/led.2017.2719280 article EN IEEE Electron Device Letters 2017-06-23

Carbon–carbon bond-forming reductive elimination from elusive organocopper(III) complexes has been considered the key step in many copper-catalyzed and organocuprate reactions. However, with well-defined structures that can undergo are extremely rare, especially for formation of Csp3–Csp3 bonds. We report herein a general method synthesis series [alkyl-CuIII-(CF3)3]− complexes, which have unequivocally characterized by NMR spectroscopy, mass spectrometry, X-ray crystal diffraction. At...

10.1021/jacs.8b12632 article EN Journal of the American Chemical Society 2019-01-25

5,14-Diaryldiindeno[2,1-f:1′,2′-j]picene (DDP, 1), a thermally and chemically stable helical arene, can be prepared from 1,4-bis[2-(arylethynyl)phenyl]benzene in four synthetic steps. Its backbone, which incorporates an o-quinodimethane moiety, was verified by X-ray crystallography, this structural feature results very high barrier to racemization (exceeding 50 kcal/mol). DDP possesses versatile promising properties, including small HOMO–LUMO energy gap (1.31 eV for the dimesityl-substituted...

10.1021/jacs.8b08840 article EN Journal of the American Chemical Society 2018-10-22

With the continuous emergence of new SARS-CoV-2 variants that feature increased transmission and immune escape, there is an urgent demand for a better vaccine design will provide broader neutralizing efficacy.We report mRNA-based using engineered "hybrid" receptor binding domain (RBD) contains all 16 point-mutations shown in currently prevailing Omicron Delta variants.A booster dose hybrid mice previously immunized with wild-type RBD induced high titers broadly antibodies against tested...

10.1186/s12929-022-00830-1 article EN cc-by Journal of Biomedical Science 2022-07-07

Despite the presence of planar chiral elements in natural products and ligands for asymmetric catalysis, catalytic enantioselective methods installing chirality remain underdeveloped relative to central axial chirality. Here, we report an Pd-catalyzed C–O bond-forming macrocyclization access enantioenriched macrocyclic metacyclophanes incorporating 2,3,4-trisubstituted pyridines. A variety bridging chains substituents can be incorporated under same reaction conditions (14 examples, 59–85%...

10.1021/acscatal.3c01147 article EN ACS Catalysis 2023-05-18

The fabrication and testing of the first semiconductor transistors small-scale integrated circuits (ICs) to achieve up 3000 h stable electrical operation at 500degC in air ambient is reported. These devices are based on an epitaxial 6H-SiC junction field-effect transistor process that successfully high-temperature ohmic contacts, dielectric passivation, ceramic packaging. Important device circuit parameters exhibited less than 10% change over course operational testing. results establish a...

10.1109/led.2008.919787 article EN IEEE Electron Device Letters 2008-04-28

Abstract Frailty is a well-recognized geriatric syndrome with various definitions and conceptual frameworks. This study aimed to use latent class analysis discover potential subtypes of pre-frail frail older people. Data from the I-Lan Longitudinal Aging Study (ILAS), community-based cohort was used for analysis. Latent applied characterize classes or subgroups different frailty phenotypes among ILAS participants targeting adults aged 65 above, capable completing 6-meter walk, without severe...

10.1038/srep46417 article EN cc-by Scientific Reports 2017-04-11

Two distinct (4+3)-nitroxy annulations between 1,5-enynes and anthranils have been developed to access tetrahydro-1H-benzo[b]azepine derivatives; the chemoselectivity varies with types of alkynes. Terminal alkyne substrates deliver benzo[b]azepine derivatives via a novel skeletal rearrangement while internal afford products without process. To elucidate mechanism rearrangement, we performed 13C- 2H-labeling experiments identify gold-containing isobenzofulvene intermediates, but their...

10.1039/c8sc03619e article EN cc-by Chemical Science 2018-11-12

The prolonged operation of semiconductor integrated circuits (ICs) needed for long-duration exploration the surface Venus has proven insurmountably challenging to date due ∼ 460 °C, 9.4 MPa caustic environment. Past and planned landers have been limited a few hours operation, even when IC electronics basic lander are protected with heavily cumbersome pressure vessels cooling measures. Here we demonstrate vastly longer (weeks) electrical two silicon carbide (4H-SiC) junction field effect...

10.1063/1.4973429 article EN cc-by AIP Advances 2016-12-01

To evaluate the predictive validity of sarcopenia defined by Foundation for National Institutes Health (FNIH) Sarcopenia Project among Asian older adults. Data I-Lan Longitudinal Aging Study were obtained analysis. Overall, 1,839 community-dwelling people aged 50 years and older, capable completing a 6-m walk, with life expectancy more than 6 months, not institutionalized at time data collection enrolled study. subjects 65 The outcome measures all-cause mortality composite adverse which...

10.1093/gerona/glx148 article EN The Journals of Gerontology Series A 2017-07-25

This letter reports fabrication and testing of integrated circuits (ICs) with two levels interconnect that consistently achieve greater than 1000 h stable electrical operation at 500°C in air ambient. These ICs are based on 4H-SiC junction field-effect transistor technology integrates hafnium ohmic contacts TaSi <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> interconnects SiO Si xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> N...

10.1109/led.2016.2544700 article EN IEEE Electron Device Letters 2016-03-22

In the AdS/CFT context, entanglement of purification (EoP) CFT is conjectured to be dual wedge cross section (EWCS) in bulk. However, another quantity called reflected entropy $S_{R}$ also supposed two times EWCS. A natural question whether they are same holographic CFTs even though different general. Previous studies have shown $\mathrm{EoP} \ge \frac{1}{2} S_{R}^{n}, n \ge2$ for random tensor networks. this paper, we study inequality beyond $n 2$, and focus on range $0 < 2$. calculations...

10.48550/arxiv.2501.10944 preprint EN arXiv (Cornell University) 2025-01-18
Coming Soon ...