A5101580516- interferon and immune responses
- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- Gastrointestinal Tumor Research and Treatment
- Nuclear Receptors and Signaling
- Intracerebral and Subarachnoid Hemorrhage Research
- Neuropeptides and Animal Physiology
- Bone health and osteoporosis research
- Caveolin-1 and cellular processes
- Neuroscience and Neuropharmacology Research
- Neurological Disease Mechanisms and Treatments
- Cancer Cells and Metastasis
- Brain Metastases and Treatment
- Electromagnetic Fields and Biological Effects
- Inflammatory mediators and NSAID effects
- Circular RNAs in diseases
- Estrogen and related hormone effects
- Cerebrovascular and Carotid Artery Diseases
- Synthesis and Catalytic Reactions
- MicroRNA in disease regulation
- Leaf Properties and Growth Measurement
- Lung Cancer Treatments and Mutations
- Immune Cell Function and Interaction
- Barrier Structure and Function Studies
- Thyroid Cancer Diagnosis and Treatment
Nanjing General Hospital of Nanjing Military Command
2025
Fudan University
2024
First Affiliated Hospital of Jinan University
2023
Shanghai Ship and Shipping Research Institute
2022
Tongji Hospital
2022
Huazhong University of Science and Technology
2022
University of Warwick
2020
Xuzhou Medical College
2020
Nanjing Medical University
2019
Jiangsu Province Hospital
2019
Our team has previously found that the stimulator of interferon genes (STING) plays a more significant anti-tumor role in host immune cells than tumor cells. Although STING is necessary for CD8 + T to exert immunological activity, its effect on remains debatable. In this study, we used both vitro and vivo models explore metabolic effects Peripheral blood lymphocytes were procured from non-small cell lung cancer (NSCLC) patients receiving anti-PD-1 therapy investigate correlation between...
Pulsed electromagnetic fields (PEMF) can promote bone healing, while use of dexamethasone induces loss and osteoporosis. There is no report available on the combined effects PEMF activity osteoblasts. Here, we investigated proliferation differentiation MC3T3-E1 Our results showed that respectively increased decreased osteoblasts, meanwhile eliminated effect Moreover, also found with upregulated mRNA expression IGF-1 at early stage after stimulation improved decrease COX-2 induced by late...
Glioma represents the most prevalent malignant primary brain cancer, and its treatment remains a tremendous challenge. Novel efficient molecular targets are therefore required for improving diagnosis, survival prediction, outcomes. Additionally, some studies have shown that immunity is highly associated with glioma progression. Our study aimed to investigate clinicopathological features, prognostic significance, immunotherapeutic targetability of ELK3, member erythroblast...
Abstract Background Lower grade glioma (LGG) is the most frequent primary tumors of central nervous system and has been a major healthcare burden, however, specific molecular mechanism underlying its initiation progression remains to be elucidated. Although it known that microRNAs (miRNAs) are widely involved in regulation malignant phenotypes glioma, underling for miRNA dysregulation largely unanswered. Methods In present work, we developed novel strategy obtain genome wide copy number...
Brain metastases (BMs) are common complications in patients with non-small cell lung cancer (NSCLC). The purpose of this study was to investigate whether the metabolic parameters derived from preoperative 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) can predict BM development surgically resected NSCLC.We retrospectively reviewed 128 consecutive stage I-IIIA NSCLC who underwent 18F-FDG PET/CT before curative surgery at First Affiliated Hospital...
Gliomas are the most intrinsic type of primary intracranial tumors. The protein encoded by calponin 3 (CNN3) has been proven to be a member family. Its relationships with cervical cancer, colorectal gastric and colon cancer have emphasized several studies. Our research aims explore prognosis value immunotherapeutic targetability CNN3 in glioma patients using bioinformatics approach.CNN3 expression was analyzed based on GEO TCGA datasets. Gene profiling clinical information employed...
Objective: To investigate the related risk factors for hemorrhagic transformation (HT) of cerebellar infarction after posterior fossa decompression surgery. Methods: A total 91 patients with were treated by surgery in Department Neurosurgery Jinhua Municipal Central Hospital from Jan 2010 to 2018, selected as study subjects. The HT group included 17 cases, while Non-HT 74 cases. clinical data two groups analyzed retrospectively, univariate and non-conditional lgistic regression analysis...