- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiac Structural Anomalies and Repair
- Infective Endocarditis Diagnosis and Management
- Cardiac pacing and defibrillation studies
- Cardiomyopathy and Myosin Studies
- Cardiovascular Effects of Exercise
- Acute Myocardial Infarction Research
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Pulmonary Hypertension Research and Treatments
- Congenital Heart Disease Studies
- Parathyroid Disorders and Treatments
- Diphtheria, Corynebacterium, and Tetanus
- Antiplatelet Therapy and Cardiovascular Diseases
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Ultrasound in Clinical Applications
- Engineering Diagnostics and Reliability
- Aortic aneurysm repair treatments
- Coronary Interventions and Diagnostics
- Streptococcal Infections and Treatments
- Aortic Disease and Treatment Approaches
- Eosinophilic Disorders and Syndromes
- Angiogenesis and VEGF in Cancer
Rabin Medical Center
2010-2024
Tel Aviv University
2011-2024
Leiden University Medical Center
2020-2024
Leiden University
2021
Aims The effect of right ventricular (RV) pacing on tricuspid regurgitation (TR) is debatable and presumed to be related an interference with valve closure by the electrode. aim study was determine impact per se TR grade.
Noninvasive evaluation of indexes right ventricular (RV) myocardial work (RVMW) derived from RV pressure-strain loops may provide novel insights into function in precapillary pulmonary hypertension. This study was designed to evaluate the association between RVMW and invasive parameters heart catheterization all-cause mortality. analysis completed 51 patients (mean age 58.1 ± 12.7 years, 31% men) with group I or IV global index (RVGWI), constructive (RVGCW), wasted (RVGWW), efficiency...
Background: Assessment of left ventricular (LV) function in patients with secondary mitral regurgitation (SMR) remains challenging but is an important parameter for risk stratification. The association LV myocardial work components (work index [GWI], constructive [GCW] and wasted [GWW] work, efficiency) derived from pressure-strain loops obtained speckle tracking echocardiography, all-cause mortality SMR was investigated. Methods: GWI, GCW, GWW, global efficiency were measured strain...
Highlights•At baseline after STEMI, LVEF and LVGLS are on average preserved or mildly reduced.•At 1 year STEMI LV systolic function has improved in most patients.•A >7% relative decrease is linked to 2.5 times higher all-cause mortality.AbstractIntroductionAfter ST-segment elevation myocardial infarction (STEMI), follow-up imaging currently recommended only patients with left ventricular ejection fraction (LVEF) <40%. Left global longitudinal strain (LVGLS) was shown improve risk...
Degenerative mitral stenosis (DMS) is associated with a poor prognosis. Although mean transmitral gradient (TMG) has shown good correlation outcome, little known about the association between other echocardiographic parameters and prognosis in patients DMS. The current study aimed to evaluate prognostic value of left atrial volume index (LAVI) DMS.A total 155 DMS (72[63-80] years, 67% female) were included. population was divided according LAVI: normal-sized LAVI (LAVI ≤ 34 ml/m2); enlarged...
Background: Disopyramide is a class Ia antiarrhythmic drug that has been used for the second-line treatment of symptomatic hypertrophic obstructive cardiomyopathy (HOCM). The aim study was to assess impact short-acting disopyramide in patients with (HOCM) using two-dimensional speckle-tracking echocardiography. Methods: This prospective included HOCM on chronic disopyramide. Two sequential comprehensive echocardiographic examinations were performed: after temporary suspension and 2.5 h...
ST-segment elevation myocardial infarction (STEMI) often leads to changes in right ventricular (RV) function and size over time. The prognostic implications of RV remodeling after STEMI, however, are unknown. patients who underwent STEMI with primary percutaneous coronary intervention (PCI) was defined by end-systolic area (RV ESA) change at 6 months compared baseline. optimal threshold ESA (≥40%) define derived from spline curve analysis. Long-term outcomes were between without remodeling....
Little is known about the natural history of non-significant mitral and tricuspid regurgitation (MR TR) following surgical aortic valve replacement (SAVR) for (AR). We retrospectively analyzed 184 patients (median age 64 (IQR, 55–74) years, 76.6% males) who underwent SAVR AR. Subjects with significant non-aortic valvulopathies, prior/concomitant valvular interventions, or congenital heart disease were excluded. The cohort was evaluated MR/TR progression and, based on latter’s occurrence,...
Mitral valve prolapse (MVP) is a common valvular disease, which may remain benign condition for long period of time. However, some patients experience malignant ventricular arrhythmias and sudden cardiac death (SCD). It still largely unknown how to risk-stratify these patients, no specific recommendations have been proposed help the clinical decision-making. We present case young man whose first presentation was an out-of-hospital arrest subsequently diagnosed with MVP. highlighted possible...
Abstract Funding Acknowledgements None BACKGROUND Aortic stenosis (AS) classification depends on left-ventricular ejection-fraction (LVEF &lt;≥50%), aortic valve area (AVA&lt;≥1cm2), mean pressure gradient (MG&lt;≥40mmHg), peak velocity&lt;≥400 cm/sec, and stroke-volume index (SVI&lt;≥35ml/m2). Valve Agatston CT score (AVC) correlates with AS severity by trans-thoracic echo (TTE), but its association determined integrated TTE TEE is unknown. PURPOSE We investigated...
Background: The prognostic significance of pulmonary venous (PV) flow reversal in degenerative mitral regurgitation (dMR) is not well-established. Objective: We aimed to assess whether reversed PV associated with adverse outcomes patients significant dMR. Methods: retrospectively analyzed consecutive referred a tertiary center for evaluation dMR greater than moderate degree, who had normal sinus rhythm, left ventricular ejection fraction above 60%, and did suffer from any other major...
Abstract Background/Introduction ST-elevation myocardial infarction (STEMI) remains a healthcare burden not only through increased mortality risk, but also development of chronic cardiac pathologies like atrial fibrillation (AF). Left (LA) reservoir strain is known predictor incident AF in the general population. Purpose Our aim was to explore additional prognostic value LA measured by transthoracic echocardiography (TTE) STEMI patients for new-onset (NOAF). Methods Data were analyzed...