A5088022410- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Pulmonary Hypertension Research and Treatments
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Atrial Fibrillation Management and Outcomes
- Congenital Heart Disease Studies
- Cardiovascular Health and Disease Prevention
- Cardiac Arrhythmias and Treatments
- Blood Pressure and Hypertension Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Disease and Adiposity
- Cardiac pacing and defibrillation studies
- Lipoproteins and Cardiovascular Health
- Peripheral Artery Disease Management
- Coronary Interventions and Diagnostics
- Cardiovascular Effects of Exercise
- Cardiomyopathy and Myosin Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Heart Failure Treatment and Management
- Acute Myocardial Infarction Research
- Advanced X-ray and CT Imaging
- Cardiovascular and exercise physiology
- Cardiovascular Issues in Pregnancy
The University of Notre Dame Australia
2016-2025
The University of Western Australia
1998-2024
University of Notre Dame
2018-2024
Fiona Stanley Hospital
2024
The University of Sydney
2017-2023
Australian Centre for Heart Health
2012-2023
Royal Prince Alfred Hospital
2017-2023
Mount Medical Centre
2016-2021
Flinders University
2019
Royal Darwin Hospital
2019
Brachial artery ultrasound is commonly employed for noninvasive assessment of endothelial function. However, analysis observer dependent and susceptible to errors. We describe studies on a computerized edge-detection wall-tracking software program allow more accurate reproducible measurement. In study 1, three purpose-built Perspex phantom arteries, 3.00, 4.00, 6.00 mm in diameter, were measured with the software. There was mean bias 11 μm ( P < 0.001 at each level) between known values;...
<h3>Background</h3> Pulmonary hypertension (PHT) lacks community prevalence and outcome data. <h3>Objective</h3> To characterise minimum ‘indicative’ prevalences mortality data for all forms of PHT in a selected population with an elevated estimated pulmonary artery systolic pressure (ePASP) on echocardiography. <h3>Design</h3> Observational cohort study. <h3>Setting</h3> Residents Armadale the surrounding region Western Australia (population 165 450) referred to our unit transthoracic...
Multiple applications for machine learning and artificial intelligence (AI) in cardiovascular imaging are being proposed developed. However, the processes involved implementing AI highly diverse, varying by modality, patient subtype, features to be extracted analyzed, clinical application. This article establishes a framework that defines value from an organizational perspective, followed chain analysis identify activities which might produce greatest incremental creation. The various...
We investigated the sex-based risk of mortality across spectrum left ventricular ejection fraction (LVEF) in a large cohort patients Australia.Quantified levels LVEF from 237 046 women (48.1%) and 256 109 men undergoing first-time, routine echocardiography (2000-2019) were linked to 119 232 deaths (median 5.6 years follow-up). Overall, 17.6% vs. 8.3% had an <50%. An <40% was associated with highest crude cardiovascular-related all-cause at 5 (∼20-30% ∼ 40-50%, respectively). Thereafter,...
Abstract Aims To examine the characteristics/prognostic impact of diastolic dysfunction (DD) according to 2016 American Society Echocardiography (ASE) and European Cardiovascular Imaging (ESCVI) guidelines, individual parameters DD. Methods results Data were derived from a large multicentre mortality-linked echocardiographic registry comprising 436 360 adults with ≥1 function measurement linked 100 597 deaths during 2.2 million person-years follow-up. ASE/European Association (EACVI)...
The mortality risk attributable to moderate aortic stenosis (AS) remains incompletely characterized and has historically been underestimated. We aim evaluate the association between AS all-cause death, comparing it with no/mild (in a general referral population in patients heart failure reduced ejection fraction).
Noninvasive evaluation of indexes right ventricular (RV) myocardial work (RVMW) derived from RV pressure-strain loops may provide novel insights into function in precapillary pulmonary hypertension. This study was designed to evaluate the association between RVMW and invasive parameters heart catheterization all-cause mortality. analysis completed 51 patients (mean age 58.1 ± 12.7 years, 31% men) with group I or IV global index (RVGWI), constructive (RVGCW), wasted (RVGWW), efficiency...
Objective To estimate the population prevalence and treatable burden of severe aortic stenosis (AS) in UK. Methods We adapted a contemporary model profile symptomatic asymptomatic AS Europe North America to number people aged ≥55 years UK who might benefit from surgical valve replacement (SAVR) or transcatheter implantation (TAVI). Results With point 1.48%, we that 291 448 men women had 2019. Of these, 68.3% (199 059, 95% CI 1 77 201 221 355 people) would have been and, therefore, more...
Aims Atrial functional mitral regurgitation (AFMR) is characterised by left atrial and consequent annular dilatation causing regurgitation. AFMR likely to become more common with population ageing, alongside increases in fibrillation heart failure preserved ejection fraction; conditions dilatation. Here, we aim define the prevalence characterise patient survival characteristics of National Echocardiographic Database Australia (NEDA). Methods results 14 004 adults moderate or severe FMR were...
Over 18 million people worldwide were diagnosed with cancer in 2020, including over 150,000 Australia. Although improved early detection and treatment have increased the survival rates, cardiotoxic inadequate management of cardiovascular risk factors resulted disease (CVD) being one leading causes non-cancer-related death disability among survivors. International guidelines outline standards care for CVD surveillance management. However, Australian cardio-oncology policies clinical are...
We sought to determine the prevalence of pulmonary complications and especially arterial hypertension (PAH) in an Australian scleroderma population.Between July 2005 June 2007, physicians Western Australia were asked refer patients with specifically for screening. All assessed PAH other respiratory conditions using echocardiography, lung function testing clinical assessments. Right heart catheterization was carried out evidence increased right ventricular systolic pressure.Of 184 analysed,...
BackgroundAortic stenosis is the most common cardiac valve disorder requiring clinical management. However, there little evidence on societal cost of progressive aortic stenosis. We sought to quantify burden premature mortality associated with progressively worse stenosis.MethodsIn this observational cohort study, we examined echocardiograms native valves 98 565 men and 99 357 women aged 65 years or older across 23 sites in Australia, from Jan 1, 2003, Dec 31, 2017. Individuals were grouped...
Objective The significance of pulmonary hypertension (PHT) complicating aortic stenosis (AS) is poorly characterised. In a large cohort adults with at least moderate AS, we aimed to describe the prevalence and prognostic importance PHT in such patients. Methods this retrospective study, analysed National Echocardiography Database Australia (data from 2000 2019). Adults an estimated right ventricular systolic pressure (eRVSP), left ejection fraction (LVEF) >50% or greater AS were included...