Keith Pearce

ORCID: 0009-0007-0017-0447
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About
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Research Areas
  • Nuclear physics research studies
  • Cardiac Imaging and Diagnostics
  • Cardiac Valve Diseases and Treatments
  • Cardiovascular Function and Risk Factors
  • Nuclear Physics and Applications
  • Ultrasound in Clinical Applications
  • Atomic and Molecular Physics
  • Cardiac, Anesthesia and Surgical Outcomes
  • Advanced MRI Techniques and Applications
  • Infective Endocarditis Diagnosis and Management
  • Cardiac Structural Anomalies and Repair
  • X-ray Spectroscopy and Fluorescence Analysis
  • Cardiac Arrhythmias and Treatments
  • Cardiovascular Effects of Exercise
  • Astronomical and nuclear sciences
  • Advanced Chemical Physics Studies
  • Quantum Chromodynamics and Particle Interactions
  • Rare-earth and actinide compounds
  • Aortic Disease and Treatment Approaches
  • Hemodynamic Monitoring and Therapy
  • Congenital Heart Disease Studies
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Mechanical Circulatory Support Devices
  • Cardiac pacing and defibrillation studies
  • Pericarditis and Cardiac Tamponade

Manchester University NHS Foundation Trust
2018-2025

Wythenshawe Hospital
2011-2023

University of Manchester
2012-2023

Manchester University
2021

University Foundation
2021

American Society of Echocardiography
2019

Manchester Metropolitan University
2015

Manchester Academic Health Science Centre
2014

Royal Liverpool University Hospital
2008

University of Liverpool
2008

Abstract Aims To describe the cardiac abnormalities in patients with COVID-19 and identify characteristics of who would benefit most from echocardiography. Methods results In a prospective international survey, we captured echocardiography findings presumed or confirmed between 3 20 April 2020. Patient characteristics, indications, findings, impact on management were recorded. Multivariable logistic regression identified predictors echocardiographic abnormalities. A total 1216 [62 (52–71)...

10.1093/ehjci/jeaa178 article EN cc-by European Heart Journal - Cardiovascular Imaging 2020-06-02

Abstract The structure and function of the right side heart is influenced by a wide range physiological pathological conditions. Quantification parameters important in variety clinical scenarios including diagnosis, prognostication, monitoring response to therapy. Although echocardiography remains first-line imaging investigation for assessment, published guidance relatively sparse comparison that left ventricle. This guideline document from British Society Echocardiography describes...

10.1530/erp-19-0051 article EN cc-by Echo Research and Practice 2020-02-27

Since cardiac ultrasound was introduced into medical practice around the middle twentieth century, transthoracic echocardiography has developed to become a highly sophisticated and widely performed imaging modality in diagnosis of heart disease. This evolution from an emerging technique with limited application, complex capable detailed assessment been driven by technological innovations that have both refined 'standard' 2D Doppler led development new diagnostic techniques. Accordingly,...

10.1530/erp-20-0026 article EN cc-by Echo Research and Practice 2020-10-20

The guideline provides a practical step-by-step guide in order to facilitate high-quality echocardiographic studies of patients with aortic stenosis. In addition, it addresses commonly encountered yet challenging clinical scenarios and covers the use advanced techniques, including TOE Dobutamine stress echocardiography assessment

10.1530/erp-20-0035 article EN cc-by Echo Research and Practice 2021-03-01

Objective To estimate the population prevalence and treatable burden of severe aortic stenosis (AS) in UK. Methods We adapted a contemporary model profile symptomatic asymptomatic AS Europe North America to number people aged ≥55 years UK who might benefit from surgical valve replacement (SAVR) or transcatheter implantation (TAVI). Results With point 1.48%, we that 291 448 men women had 2019. Of these, 68.3% (199 059, 95% CI 1 77 201 221 355 people) would have been and, therefore, more...

10.1136/openhrt-2021-001783 article EN cc-by-nc Open Heart 2022-01-01
Ben O’Brien Niall Campbell Elizabeth Allen Zahra Jamal Joanna Sturgess and 95 more Julie Sanders Charles Opondo Neil Roberts Jonathan Aron Maria Maccaroni Richard Gould Bilal H. Kirmani Ben Gibbison Gudrun Kunst Alexander Zarbock Maren Kleine‐Brueggeney Christian Stoppe Keith Pearce Mark Hughes Laura Van Dyck Richard Evans Hugh Montgomery Diana Elbourne Robert B. Henderson Jatin Desai David Keane Kurt Ruetzler Steven Stevenson R David Martinez Duncker Rosalie Magboo Nicholas Barrett Philip M. Jones Ly‐Mee Yu Bob Kiaii Trudie Lobban Julie Sanders Neil Roberts Sophie Welch Christabel Williams Gemma Hughes Victoria Baker F.J. Parrondo García Chrysanthos Sfakianakis Melissa Baldey Carmen K. M. Chan Jorge Couto de Sousa Hakam Abbass Niall Campbell Linda Kimani Lajos Szentgyörgyi Louise Rankin Efstratios Athanasakis Akhila Muthuswamy Alison Allanson Anna Lewis Arron Finch Folakemi Fowe Lahja Paulus Bisma Chellam Singh Preetha Mathew Reshma Dutt Sunil Jesha Mathews Sheetal Crasta Susan M. Ferguson Schvearn Allen Seema Pokharel Anie Nicholas Adam Pailing Gudrun Kunst Harriet Noble Sian Saha Kevin O’Reilly Caitlin Spooner Emma Clarey Clare Finney Anna Broderick Maria Theresa Depante Daveena Meeks Paraskevi Pappa Laura-Anne Dymore-Brown Rebecca Samuels Tajwinder Sandhar Fatemeh Karami Annette Axalan Burt Vergara Eleanor Corcoran Mahmoud Loubani Sarah L. Ford Kay Rowe Karen Dobbs Jeanne Bulemfu Paul Harper J. Sanders Gregory Lip Bilal H. Kirmani Maureen Baker Lynne Keogan Abinash Panda Agnieszka Kotalczyk Ameenathul M. Fawzy

IMPORTANCE Supplementing potassium in an effort to maintain high-normal serum concentrations is a widespread strategy used prevent atrial fibrillation after cardiac surgery (AFACS), but not evidence-based, carries risks, and costly. OBJECTIVE To determine whether lower concentration trigger for supplementation noninferior trigger. DESIGN, SETTING, AND PARTICIPANTS This open-label, noninferiority, randomized clinical trial was conducted at 23 surgical centers the United Kingdom Germany....

10.1001/jama.2024.17888 article EN JAMA 2024-08-31

To assess the impact of "real-world" practice variation in process quantifying left ventricular (LV) mass, volume indices, and ejection fraction (EF) from steady-state free precession cardiovascular magnetic resonance (CMR) images. The utility LV geometric modeling techniques was also assessed.The effect short-axis- versus long-axis-derived base identification, simplified detailed endocardial contouring, visual automated identification end-systole were evaluated using CMR images 50...

10.1002/jmri.23892 article EN Journal of Magnetic Resonance Imaging 2012-11-02

Background: Artificial intelligence (AI) for echocardiography requires training and validation to standards expected of humans. We developed an online platform established the Unity Collaborative build a dataset expertise from 17 hospitals training, validation, standardization such techniques. Methods: The consisted 2056 individual frames drawn at random 1265 parasternal long-axis video-loops patients undergoing clinical in 2015 2016. Nine experts labeled these images using our platform....

10.1161/circimaging.120.011951 article EN cc-by Circulation Cardiovascular Imaging 2021-05-01

Abstract Background/Introduction Recent guidelines and randomised controlled trials have proposed less frequent use of invasive strategies for patients with stable chest pain, demonstrated the non-inferiority an initial medical management strategy. However, impact these updates on clinical practice in United Kingdom has not been previously reported. Purpose We aimed to identify if recent literature changed being referred stress echocardiography assess inducible ischaemia a real-world,...

10.1093/ehjci/jeae333.335 article EN European Heart Journal - Cardiovascular Imaging 2025-01-01

Abstract Introduction The British Society of Echocardiography National Review Stress Echo Practice (BSE N-STEP) is a large, prospective, multicentre study investigating stress echocardiography (SE) practice within the UK Health Service. We used this dataset to identify, categorise and compare characteristics workforce groups delivering SE real-world cohort. Method Recruitment occurred between September 2020 June 2023 across 34 NHS trusts. All patients provided informed consent underwent...

10.1093/ehjci/jeae333.342 article EN European Heart Journal - Cardiovascular Imaging 2025-01-01

Abstract Aims To assess the real world impact of updated clinical guidelines and literature on management patients undergoing stress echocardiography for assessment inducible ischaemia across a national health service. Methods Results A total 13,819 from 32 UK hospitals, referred between 2015-2023, were analysed two phases: phase 1 (2015-2020) 2 (2020-2023). Follow-up data one year was available 4,920 participants through NHS Digital. Patients in younger, presented with higher cardiovascular...

10.1093/ehjci/jeaf099 article EN cc-by European Heart Journal - Cardiovascular Imaging 2025-03-22

Abstract Background Work-related musculoskeletal pain (WRMSP) is increasingly recognised in cardiac ultrasound practice. WRMSP can impact workforce health, productivity and sustainability. We sought to investigate the prevalence, characteristics clinical of WRMSP. Methods Prospective electronic survey 157 echocardiographers 10 institutions. Data acquired on demographics, experience, working environment/pattern, location, severity pattern, professional, personal life career. Results 129/157...

10.1186/s44156-024-00042-3 article EN cc-by Echo Research and Practice 2024-03-06

The subspecialty of cardio-oncology aims to reduce cardiovascular morbidity and mortality in patients with cancer or following treatment. Cancer therapy can lead a variety complications, including left ventricular systolic dysfunction, pericardial disease, valvular heart disease. Echocardiography is key diagnostic imaging tool the diagnosis surveillance for many these complications. baseline assessment subsequent undergoing treatment anthracyclines and/or human epidermal growth factor (EGF)...

10.1530/erp-21-0001 article EN cc-by Echo Research and Practice 2021-03-01

Echocardiography (echo) is central to the assessment and management of all cardiac diseases. An echocardiogram produced using ultrasound waves create a moving picture heart. It innate advantages this medium (sound are harmless painless, portable systems allow convenience with instant, reproducible results) that allows its use continue flourish widely beyond traditional hospital settings. Increasing patient multimorbidity resulting from an ageing population driving increase in demand for...

10.3399/bjgp19x704513 article EN British Journal of General Practice 2019-06-27

Abstract The British Society of Echocardiography has previously outlined a minimum dataset for standard transthoracic echocardiogram, and this remains the basis on which an echocardiographic study should be performed. importance ultrasound in excluding critical conditions that may require urgent treatment is well known. Several point-of-care echo protocols have been developed use by non-echocardiography specialists. However, these are often only used specific circumstances usually limited to...

10.1530/erp-19-0060 article EN cc-by Echo Research and Practice 2020-03-12

Heart valve disease has been described as 'the next cardiac epidemic', with prevalence expected to double by 2040 and triple 2060 due the ageing of population. Yet until now, it characterized scarce data, limited research, low general awareness compared other cardiovascular diseases. Effective treatment options exist for heart disease, early detection can dramatically change progression, improve quality life, reduce mortality. Unfortunately, in too many patients, is undetected, undiagnosed,...

10.1093/ehjopen/oeab034 article EN cc-by-nc European Heart Journal Open 2021-11-01

Abstract Aims Stress echocardiography is widely used to assess patients with chest pain. The clinical value of a positive or negative test result inform on likely longer-term outcomes when applied in real-world practice across healthcare system has not been previously reported. Methods and results Five thousand five hundred three recruited 32 UK NHS hospitals between 2018 2022, participating the EVAREST/BSE-NSTEP prospective cohort study, data medical up 2023 available from England were...

10.1093/ehjci/jeae291 article EN cc-by European Heart Journal - Cardiovascular Imaging 2024-11-12

New measurements are presented of the ground-state mass 22F derived from 22Ne(t,3He)22F reaction at Et=33.4 MeV. Twenty two levels have been identified in and excitation energies determined. Some J values for states assigned DWBA calculations, compared with shell model predictions.

10.1088/0305-4616/14/11/011 article EN Journal of Physics G Nuclear Physics 1988-11-01

36 MeV triton elastic scattering data have been obtained for targets of 30Si, 28Si, 26Mg, 16O and 12C. These are analysed in terms a conventional phenomenological optical model double-folding model.

10.1088/0305-4616/12/10/009 article EN Journal of Physics G Nuclear Physics 1986-10-01
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