A5072414645- Sinusitis and nasal conditions
- Nasal Surgery and Airway Studies
- Obstructive Sleep Apnea Research
- Mycobacterium research and diagnosis
- Antimicrobial Peptides and Activities
- Beetle Biology and Toxicology Studies
- Hearing, Cochlea, Tinnitus, Genetics
- Olfactory and Sensory Function Studies
- Vestibular and auditory disorders
- Neutropenia and Cancer Infections
- Allergic Rhinitis and Sensitization
- Ophthalmology and Eye Disorders
- Surgical site infection prevention
- Head and Neck Surgical Oncology
- Tracheal and airway disorders
- Cystic Fibrosis Research Advances
- Asthma and respiratory diseases
- Head and Neck Cancer Studies
- Infectious Diseases and Mycology
- Plant Disease Resistance and Genetics
- Atmospheric aerosols and clouds
- Immunotherapy and Immune Responses
- Meningioma and schwannoma management
- Blood disorders and treatments
- CAR-T cell therapy research
University of British Columbia
2021-2024
Instituto Nacional de Rehabilitación
2017-2022
Instituto Nacional de Cancerología
2017
Universidad Nacional Autónoma de México
2012-2013
Temple University
1999
Objective To investigate the frequency and nature of adverse events related to type 2 biologic use in patients with chronic rhinosinusitis nasal polyps (CRSwNP), including dupilumab mepolizumab. Methods This is a single‐institution retrospective study real‐world patient data. Patients were included if they have diagnosis CRSwNP, undergone at least one endoscopic sinus surgery, taken two doses or mepolizumab between January 1, 2016, July 2023. Data collected include clinicodemographic...
Objective: Compare the caloric vestibular test (CVT) and video head impulse (vHIT) in evaluation of Meniere's disease (MD) to analyze their diagnostic accuracy.Materials methods: Retrospective review CVT vHIT performed MD patients at a tertiary care referral center Spain.Results: A total 88 were reviewed. The was abnormal 67% (n = 59) patients, while 66% 58) them. Agreement between both tests poor, regardless whether horizontal semicircular canal (SCC) or all SCC analyzed (kappa .21)....
Type 2 biologics have been used increasingly for the treatment of chronic rhinosinusitis with nasal polyps (CRSwNP). However, patterns biologic switching are understudied, and established guidelines sequential or simultaneous use do not yet exist. This is a Canadian multicenter retrospective study real-world patient data. Patients were included if they had recurrent CRSwNP despite maximal medical surgical management, received at least one dose type biologic. who remained on their initial...
The therapeutic efficacy of a synthetic parasite-derived peptide GK1, an immune response booster, was evaluated in mouse melanoma model. This model correlates with human stage IIb melanoma, which is treated wide surgical excision; parallel study employing treatment carried out as instructive goal.C57BL/6 mice were injected subcutaneously the flank 2×10(5) B16-F10 murine cells. When tumors reached 20 mm3, separated into two different groups; GK1 group, weekly peritumoral injections (10 μg/100...
Ectopic olfactory neuroblastoma (ONB) is a rare neuroendocrine sinonasal malignancy which arises from regions where neuroepithelium does not exist. Presentation of syndrome inappropriate antidiuretic hormone release (SIADH) in patients with ectopic ONB extremely rare. We report case 22-year-old patient and paraneoplastic SIADH that was managed at our center. The arising the left lamina papyracea extending into maxillary ethmoid sinuses filling nasal cavity. Correction sodium levels occurred...
Abstract Background Dysregulation of the airway microbiota is thought to contribute inflammation in both chronic rhinosinusitis (CRS) and asthma. However, relationship between upper lower microbiome remains unclear. Methods Sinus lung brushes were collected from 29 CRS participants undergoing sinus surgery. DNA was extracted submitted for 16s rRNA sequencing. Alpha beta diversity metrics, taxonomic composition, differences individual taxa compared paired bronchial samples. Results...
SinoNasal Microbiota Transfer (SNMT) was safe with immediate benefit in all recipients, sustained improvement two of three recipients for up to 180 days. The addition antimicrobial photodynamic therapy worsened chronic rhinosinusitis. These promising SNMT results warrant further study safety and efficacy.
Introduction Benign paroxysmal positional vertigo (BPPV) appears during the same age group in which vitamin D and calcium deficiencies are evident. Vitamin deficiency could predispose to BPPV, since these two entities share a demineralization process. Objective To establish otological impact of supplementation patients with its who suffer from BPPV. Methods This was randomized clinical trial. A total 35 (< 30 ng/ml) BPPV were divided into 2 groups: Group 1 (control group): treatment...
Although there are several endoscopic grading systems for chronic rhinosinusitis (CRS), they limited in their range and applicability. We developed a SiNonasal Endoscopic Score (SiNES) that builds upon the strengths of previous while addressing limitations.
Patients with chronic rhinosinusitis (CRS) that is refractory to maximal medical and surgical therapy should be evaluated for other primary conditions. Cystic fibrosis (CF), immunodeficiency (PID), ciliary dyskinesia (PCD) are potential risk factors CRS. These conditions present variable disease severity diagnosis may delayed into adulthood. We report a case of mother-daughter pair CRS management. The patients were further found have features consistent CF, PID, PCD. All 3 rare disorders...
Abstract Purpose: The therapeutic efficacy of a synthetic parasite-derived peptide GK1, an immune response booster, was evaluated in mouse melanoma model. This model correlates with human stage IIb melanoma, which is treated wide surgical excision, parallel study employing treatment carried out as instructive goal. Experimental Design: C57BL/6 mice were injected subcutaneously the flank 2×105 B16-F10 murine cells. When tumors reached 20 mm3, separated into two different groups: GK1 group,...
ANTECEDENTES : El manejo de la punta nasal es gran importancia en rinoplastia. La sutura septocolumelar puede ayudar al cirujano a mejorar proyeccion y rotacion como parte del nasal. OBJETIVO Determinar los cambios transquirurgica con el uso septocolumelar. MATERIAL Y METODO Estudio cuasiexperimental antes despues. Se incluyeron pacientes programados para rinoplastia primaria abril agosto 2017. Posterior nasal, se analizaron fotografias pre posaplicacion punto forma transquirurgica. evaluo...