A5086339366- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Research on Leishmaniasis Studies
- Antimicrobial Peptides and Activities
- Immunotherapy and Immune Responses
- Entomopathogenic Microorganisms in Pest Control
- Plant-Microbe Interactions and Immunity
- Plant Pathogens and Fungal Diseases
- Urticaria and Related Conditions
- Cancer Research and Treatments
- Phytoplasmas and Hemiptera pathogens
- Eosinophilic Disorders and Syndromes
- Virology and Viral Diseases
- Trypanosoma species research and implications
- Influenza Virus Research Studies
- Mast cells and histamine
- Cancer Cells and Metastasis
- Respiratory viral infections research
- Virus-based gene therapy research
- Insect Pest Control Strategies
- Effects and risks of endocrine disrupting chemicals
- Essential Oils and Antimicrobial Activity
- Galectins and Cancer Biology
- Insect symbiosis and bacterial influences
- Liver physiology and pathology
Universidad Nacional Autónoma de México
2015-2024
Universidad Autónoma de la Ciudad de México
2023
Hospital de Sagunto
2014
Bursera morelensis is used in Mexican folk medicine to treat wounds on the skin. Recently, it was shown that essential oil (EO) of B. has wound healing activity, accelerating cutaneous closure and generating scars with good tensile strength. α-pinene (PIN) α-phellandrene (FEL) are terpenes have been found this EO, different studies both anti-inflammatory activity. The aim study determine activity these two terpenes. results vitro tests demonstrate PIN FEL not cytotoxic at low concentrations...
Bursera morelensis is used in Mexican folk medicine to treat wounds on the skin. It an endemic tree known as “aceitillo”, and antibacterial antifungal activity of its essential oil has been verified; it also acts anti-inflammatory. All these reported biological activities make B. a candidate accelerate wound-healing process. The objective was determine properties morelensis’ murine model. obtained by hydro-distillation, chemical analysis performed gas chromatography-mass spectrometry...
Sporothrix schenckii is the etiological agent of sporotrichosis, a subcutaneous mycosis and an emerging disease in immunocompromised patients. Adherence to target cells prerequisite for fungal dissemination systemic complications. However, information on cell surface components involved this interaction rather scarce. In investigation, extraction isolated walls from yeast phase S. with SDS separation proteins by SDS-PAGE led identification periodic acid-Schiff (PAS)-reacting 70 kDa...
Breast cancer (BC) metastasis represents the main physiopathology leading to poor prognosis and death. Bisphenol A (BPA) is a pollutant, classified as an endocrine-disrupting chemical compound with estrogenic properties, their exposure in early stages of neonatal life leads increase size weight breast tumors induces cellular changes tumoral immune microenvironment where cytokines play key role. Thus, we used female BALB/c mice exposed neonatally single dose BPA. Once reached sexual maturity,...
Triatomine insects are vectors of Trypanosoma cruzi, the causal agent Chagas disease. The insect-parasite interaction has been studied in relation to transmission and prevalence this For most triatomines, however, several crucial aspects insect immune response still unknown. example, only for Rhodnius prolixus Triatoma infestans activity phenoloxidase (PO) its zymogen prophenoloxidase (proPO) reported hemolymph anterior midgut (AM). aim study was gain insight into T. cruzi infection an...
Summary Two patients with diffuse cutaneous leishmaniasis caused by Leishmania mexicana were treated two leishmanicidal drugs (pentamidine and allopurinol) combined recombinant interferon‐γ restoring Th‐1 favouring conditions in the patients. Parasites decreased dramatically lesions macrophages diminished concomitantly, while IL‐12‐producing Langerhans cells interferon‐γ– producing NK CD8 + lymphocytes increased a reciprocal manner. The CD4+/CD8 ratio peripheral blood normalized. During...
SUMMARY The regulatory effect of mast cells on the pathogenesis leishmaniasis is unclear. We report a comparative analysis TLR2 membrane expression, TNF‐α, IL‐10 and MIP‐1α production, granule release bone marrow‐derived (BMMCs) from susceptible BALB/c resistant C57BL/6 mice, stimulated in vitro with Leishmania mexicana lipophosphoglycan (LPG). studied kinetics cell degranulation parasite numbers lesions both mouse strains infected L. . found that BMMCs mice expressed more produced higher...
Cell wall (CW) components of fungus Sporothrix schenckii are the major inductors antigens immune responses. The immunodominant 60 kDa glycoprotein (gp60) has been shown to be associated with virulence this but its role in experimental sporotrichosis is unknown. In work, immunological effects CW-purified gp60 were investigated a model subcutaneous normal and gp60-preimmunized C57BL/6 BALB/c mice strains which then infected S. conidia. Results showed that both use different cytokine profiles...
The therapeutic efficacy of a synthetic parasite-derived peptide GK1, an immune response booster, was evaluated in mouse melanoma model. This model correlates with human stage IIb melanoma, which is treated wide surgical excision; parallel study employing treatment carried out as instructive goal.C57BL/6 mice were injected subcutaneously the flank 2×10(5) B16-F10 murine cells. When tumors reached 20 mm3, separated into two different groups; GK1 group, weekly peritumoral injections (10 μg/100...
Prostate cancer (PCa) is the second most frequently diagnosed in men worldwide. Dialyzed Leukocyte Extracts (DLEs) are heterogeneous mixtures of low-molecular-weight peptides that improve clinical responses various diseases. Here, we analyzed effects TransferonTM, a commercial DLE with characterized active pharmaceutical ingredient and proven batch-to-batch reproducibility, preclinical models PCa. We employed v-Src-transformed murine prostate epithelial (PEC-Src) cells, which recapitulate...
More than one quarter of human world's population is exposed to intestinal helminth parasites.The Taenia solium tapeworm carrier the main risk factor in transmission both neurocysticercosis and porcine cysticercosis.Sex steroids play an important role during T. infection, particularly progesterone has been proposed as a key immunomodulatory hormone involved susceptibility taeniosis woman cysticercosis pregnant pigs.Thus, we evaluated effect administration upon experimental golden hamsters...