- Antibiotic Resistance in Bacteria
- Neutropenia and Cancer Infections
- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Use and Resistance
- Central Venous Catheters and Hemodialysis
- Antifungal resistance and susceptibility
- Urinary Tract Infections Management
- Streptococcal Infections and Treatments
- Pharmaceutical and Antibiotic Environmental Impacts
- Genomics and Phylogenetic Studies
- Bacterial biofilms and quorum sensing
- Enterobacteriaceae and Cronobacter Research
- Surgical site infection prevention
- Nanoplatforms for cancer theranostics
- Fungal Infections and Studies
- Colorectal Cancer Surgical Treatments
- Infections and bacterial resistance
- Methemoglobinemia and Tumor Lysis Syndrome
- Infective Endocarditis Diagnosis and Management
- Plant Pathogenic Bacteria Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Chemotherapy-related skin toxicity
- Pneumocystis jirovecii pneumonia detection and treatment
- Metabolism and Genetic Disorders
Instituto Nacional de Cancerología
2015-2025
Secretaria de Salud
2012-2016
We aimed to assess the resistance rates of antimicrobial-resistant, in bacterial pathogens epidemiological importance 47 Mexican centers.In this retrospective study, we included a stratified sample centers, covering 20 states. Selected isolates considered as potential causatives disease collected over 6-month period were included. Laboratories employed their usual methods perform microbiological studies. The results deposited into database and analyzed with WHONET 5.6 software.In total...
Objective To describe the clinical features, outcomes, and molecular epidemiology of an outbreak multidrug resistant (MDR) A. baumannii. Methods We performed a retrospective analysis all MDR baumannii isolates recovered during from 2011 to 2015 in tertiary care cancer hospital. Cases were classified as colonized or infected. determined sequence types following Bartual scheme plasmid profiles. Results There 106 strains isolated study period. Sixty-six (62.3%) considered infection 40 (37.7%)...
Introduction Patients with hematologic malignancies have greater risk-factors for primary bloodstream infections (BSI). Methods From 2004–2009, we analyzed bacteremia caused by extended-spectrum beta-lactamase Escherichia coli (ESBL-EC) (n = 100) and compared cephalosporin-susceptible E. in patients malignancies. Objective To assess the clinical features, risk factors, outcome of ESBL-EC BSI malignancies, to study molecular epidemiology isolates. Results The main diagnosis was acute leukemia...
The identification of carbapenemase-producing Enterobacterales and Pseudomonas aeruginosa is important for treating controlling hospital infections. recommended methods their require a long waiting time, technical training, expertise. Lateral flow immunoassays such as NG-Test CARBA 5® overcome these needs. We analyzed 84 clinical isolates carbapenem-resistant P. from four different hospitals in two-year period. Antimicrobial resistance patterns were confirmed with the broth dilution method....
Introduction The methicillin-resistant Staphylococcus aureus (MRSA) genome varies by geographical location. This study aims to determine the genomic characteristics of MRSA using whole-genome sequencing (WGS) data from medical centers in Mexico and explore associations between antimicrobial resistance genes virulence factors. Methods included 27 clinical isolates collected sterile sites at eight 2022 2023. Antibiotic susceptibility testing was performed VITEK 2. In addition, WGS a NovaSeq...
Abstract Background The inclusion of highly cytotoxic drugs for the treatment acute leukemia (AL) in last decade has exposed patients to more extended periods severe neutropenia. study aims describe prevalence and risk factors blood-stream infection (BSI) due carbapenem-resistant enterobacteria (CRE) with AL receiving chemotherapy.Table 1.Independent FLAG-IDA chemotherapy regimen had an OR 28.8 (CI 2.9-286.68. p=0.004) CRE-BSI Methods was performed at a referral center adult cancer Mexico...
Introduction Antimicrobial resistance surveillance plays an important role in generating information about the prevalence of resistant microorganisms. In this study, we summarize a antimicrobial and carbapenemase-encoding genes for selected pathogens Mexican healthcare centers. Methods Databases identification susceptibility results collected from January 1 to March 31, 2024, forty-one centers were gathered analyzed using WHONET software. Some relevant gram-negatives gram-positives, which...
The objective of the study was to detect multidrug-resistant Staphylococcus sp. and Enterococcus isolates in municipal hospital wastewater determine their elimination or persistence after treatment. Between August 2021 September 2022, raw treated samples were collected at two community treatment plants (WWTPs). In each season year, duplicate WWTPs studied. Screening presumptive identification staphylococci enterococci performed using chromoagars, with Matrix Assisted Laser Desorption...
The mortality of Candida Bloodstream Infection (CBSI) remains high. Antifungal susceptibility breakpoints were recently updated for species, the impact unknown. In this study we evaluated inappropriate antifungal treatment according to recent on 30-day CBSI. From June 2008 July 2014, data CBSI episodes from two tertiary-care centers, treated > 72 h analyzed. therapy and registered. Inappropriate current Clinical & Laboratory Standards Institute (CLSI) was adjusted with mortality-related...
Objetivo. Describir la tendencia de cepas multidrogorresistentes (MDR) aisladas en hemocultivos pacientes con cáncer durante el periodo 2005 a 2015. Material y métodos. Análisis retrospectivo que se procesaron 33 127 hemocultivos. La identificación sensibilidad antimicrobianas realizaron través métodos automatizados WaLK away (Siemens Laboratory Diagnostics) BD Phoenix (Becton, Dickinson and Company). Se determinaron resistentes acuerdo concentración mínima inhibitoria, según los...
Introduction: Oncologic patients can have severe infections due to Aeromonas. This study aims investigate the clinical characteristics and outcomes of cancer with bloodstream (BSI) caused by Methodology: We included bacteremia Aeromonas species from 2011 2018. Results: Seventy-five BSI events in same number were identified. Forty men (53.3%); mean age was 49 years (IQR 28-61). A. caviae most frequent isolate (n = 29, 38.6%), followed hydrophila 23, 30.6%), sobria 15, 20%), veronii 8, 10.6%)....
This study assessed the microbiology, clinical syndromes, and outcomes of oncologic patients with viridans group streptococci isolated from blood cultures between January 1st, 2013 December 31st, 2016 in a referral hospital Mexico using Bruker MALDI Biotyper. Antimicrobial sensitivity was determined BD Phoenix 100 according to CLSI M100 standards. Clinical information obtained medical records descriptive analysis performed. Forty-three were included, 22 females 21 males, aged 42 ± 17 years....
Acinetobacter haemolyticus is a Gammaproteobacterium that has been involved in serious diseases frequently linked to the nosocomial environment. Most of strains causing such infections are sensitive wide variety antibiotics, but recent reports indicate this pathogen acquiring very efficiently carbapenem-resistance determinants like blaNDM-1 gene, all over world. With work we contribute with collection set 31 newly sequenced A. isolates. Genome analysis these sequences and others collected...
This study describes the clinical and molecular characteristics of methicillin-resistant Staphylococcus aureus (MRSA) isolates that emerged after an index case in a tertiary-care oncology hospital Mexico City identifies whether these were related with case. All MRSA strains isolated from January 2006 until December 2007 included. The demographic patients analyzed; typing by pulsed-field gel electrophoresis was used to characterize isolates. We included 44 55 patients. Thirty-eight (86.4%)...
To describe the incidence and patterns of bacterial resistance in urine samples from a tertiary care oncology hospital Mexico, 2004 to 2013.We included strains obtained cultures, describing separately multidrug-resistant (MDR) bacteria. We analyzed susceptibility different antibiotics.51 202 cultures were processed during study; 14 480 (28.3%) positive. In 11 427 Gram negative (79%) isolated, 2 080 positive (14.4%), 973 yeasts (6.6%). Escherichia coli was most frequent bacteria identified...