A5076476105- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Trypanosoma species research and implications
- COVID-19 Clinical Research Studies
- Bacterial Identification and Susceptibility Testing
- Long-Term Effects of COVID-19
- Vector-borne infectious diseases
- Health and Lifestyle Studies
- Streptococcal Infections and Treatments
- Bacteriophages and microbial interactions
- Infections and bacterial resistance
- SARS-CoV-2 and COVID-19 Research
- Pharmaceutical and Antibiotic Environmental Impacts
- Urinary Tract Infections Management
- Obesity, Physical Activity, Diet
- Viral Infections and Vectors
- Infective Endocarditis Diagnosis and Management
- Vector-Borne Animal Diseases
- Shoulder Injury and Treatment
- Nosocomial Infections in ICU
- Mosquito-borne diseases and control
- Insect symbiosis and bacterial influences
- Neonatal and Maternal Infections
- Infectious Encephalopathies and Encephalitis
- Empathy and Medical Education
Universidad de Colima
2011-2025
Secretaria de Salud
2023
University of Illinois Urbana-Champaign
1980
Aim: This study aims to assess the changes in antimicrobial resistance among some critical and high-priority microorganisms collected previously during coronavirus disease 2019 (COVID-19) pandemic Mexico. Methods: We susceptibility data for from blood, urine, respiratory samples, all specimens, which pathogen may be considered a causative agent. Data were stratified compared two periods: versus 2020 second semester (prepandemic) (pandemic). Results: In analysis of 2020, blood increased...
We aimed to assess the resistance rates of antimicrobial-resistant, in bacterial pathogens epidemiological importance 47 Mexican centers.In this retrospective study, we included a stratified sample centers, covering 20 states. Selected isolates considered as potential causatives disease collected over 6-month period were included. Laboratories employed their usual methods perform microbiological studies. The results deposited into database and analyzed with WHONET 5.6 software.In total...
Risk factors for developing long COVID are not clearly established. The present study was designed to determine if any sign, symptom, or treatment of the acute phase, personal characteristics patient, is associated with development COVID.A cohort carried out, randomly selecting symptomatic COVID-19 patients and vaccinated. severity illness assessed through number compatible symptoms, hospitalizations, symptom score using a 10-point visual analog scale.After multivariate analysis, ≥8 (RR 2.0,...
This report presents phenotypic and genetic data on the prevalence characteristics of extended-spectrum β-lactamases (ESBLs) representative carbapenemases-producing Gram-negative species in Mexico.A total 52 centers participated, 43 hospital-based laboratories 9 external laboratories. The distribution antimicrobial resistance for Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae complex, Acinetobacter baumannii Pseudomonas aeruginosa selected clinical specimens from January 1 to...
COVID-19 vaccines primarily prevent severe illnesses or hospitalization, but there is limited data on their impact during hospitalization for seriously ill patients. In a Mexican cohort with high mortality, study assessed vaccination's effects. From 2021 to 2022, 462 patients 4455 hospital days were analyzed. The generalized multivariate linear mixed model (GENLINMIXED) binary logistic regression link, survival analysis and ROC curves used identify risk factors death. results showed that the...
Traditional and complementary medicine (T&CM) plays a significant role in healthcare practices among professionals oncology patients Mexico, reflecting its cultural importance. This study aimed to analyze the prevalence, frequency, factors associated with T&CM use these two groups, highlighting differences perceptions. A total of 382 individuals participated, including 152 230 patients. The findings revealed that while was similarly prevalent (85.7%) (90.8%), frequent (≥2 times per...
Background: Surveillance of antimicrobial resistance (AMR) requires an international approach with national and local strategies. Our aim was to summarize a retrospective 10-year report antibiotic gram-positive gram-negative bacteria in Mexico. Methods: A total 46 centers from 22 states Mexico participated. Databases AMR January 2009 December 2018 were included for most species. The period divided into five 2-year periods. Results: For Staphylococcus aureus, decrease all specimens observed...
In this study, we report the carbapenemase-encoding genes and colistin resistance in Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa second year of COVID-19 pandemic. Clinical isolates included carbapenem-resistant K. E. A. P. aeruginosa. Carbapenemase-encoding were detected by PCR. Carbapenem-resistant pneumoniae coli analyzed using Rapid Polymyxin NP assay. mcr screened Pulsed-field gel electrophoresis whole-genome sequencing performed on...
Coronavirus disease 2019 (COVID‑19) is currently the major public health problem worldwide. Neutral electrolyzed saline solution that contains reactive chlorine and oxygen species may be an effective therapeutic. In present study, treatment efficacy of intravenous and/or nebulized neutral combined with usual medical care vs. alone was evaluated in ambulatory patients COVID‑19. A prospective, 2‑arm, parallel‑group, randomized, open‑label, multi‑center, phase I‑II clinical trial including 214...
Mefenamic acid is a non‑steroidal anti‑inflammatory drug exhibiting wide range of anti‑inflammatory, antipyretic, analgesic and probable antiviral activities. The present study evaluated the efficacy treatment with mefenamic combined standard medical care vs. plus placebo in ambulatory patients coronavirus disease 2019 (COVID‑19; nasal/oropharyngeal swabs reverse transcription‑PCR test results positive for severe acute respiratory syndrome 2). phase II prospective, two‑arm, parallel‑group,...
The severity of adenovirus infection or the success adenovirus-vectorized gene therapy largely depends on efficiency viral entry into cells. Various drugs can alter entry. This study evaluated effects dexamethasone, paracetamol, diclofenac, ibuprofen, and ketorolac cells in vitro vivo. SiHa cell cultures pretreated with ketorolac, no drug were exposed to Ad-BGal vector. percentage showing vector was quantified microscopically. In vivo, BALB-C mice for 7 days intravenously (IV) via oral (VO)....
We analyzed the antimicrobial resistance (AMR) data of 6519 clinical isolates Escherichia coli (n = 3985), Klebsiella pneumoniae 775), Acinetobacter baumannii 163), Pseudomonas aeruginosa 781), Enterococcus faecium 124), and Staphylococcus aureus 691) from 43 centers in Mexico. AMR assays were performed using commercial microdilution systems (37/43) disk diffusion susceptibility method (6/43). The presence carbapenemase-encoding genes was assessed PCR. Data regarding site care, patient age,...
Background: Coronavirus disease (COVID-19) is currently the main public health problem worldwide. The administration of neutral electrolyzed saline, a solution that contains reactive species chlorine and oxygen (ROS), may be an effective therapeutic alternative due to its immunomodulating characteristics, in systemic inflammation control, as well immune response improvement, promoting control viral infection. present study evaluated efficacy treatment with intravenous and/or nebulized saline...
Fosfomycin is currently a viable option against urinary tract infections, particularly extended-spectrum β-lactamases (ESBL)-producing E. coli, due to its unique mechanism of action and low resistance among bacteria. The objective this study was investigate two the three most common mechanisms antibiotic 350 ESBL-producing coli strains isolated from urine Mexican patients. prevalence fosfomycin in our 10.9% (38/350). Of all resistant isolates analyzed, 23 (60.5%) were identified as...
Tick paralysis is a rare entity in which it necessary to identify the cause and remove arthropod have rapid remission of symptoms. In absence an early diagnosis, outcome can be fatal, as toxins are released from tick's saliva feeds. To best authors' knowledge, this first clinical report disease Mexico Latin America. A 22-year-old man rural area, who was contact with cattle, developed ascending flaccid secondary Amblyomma maculatum tick toxin. He presented paraplegia arreflexia that...
Here, we evaluated the performance of two commercial MALDI-TOF MS systems and three biochemical-based compared them to WGS as gold standard for identifying isolates vancomycin-resistant enterococci (VRE).A total 87 VRE clinical were included. The mass spectrometers Microflex system with Biotyper software 3.1 Vitek system. included 2, Phoenix, MicroScan WalkAway systems. was performed on an Illumina MiSeq instrument using v3 reagent kit. Vancomycin resistance determined according CLSI...
Despite efforts to eradicate American trypanosomiasis (AT) and Chagas disease from the Americas, there are still areas of active transmission that can eventually become a source reinfection in previously controlled regions. Mexico could be one those areas, where no formal preventive control programs despite presence communities infested by Triatominae bugs infected with Trypanosoma cruzi. This study explored prevalence T. cruzi infection 405 habitants 17 state Colima, on Pacific Mexican...
To determine genomic characteristics and molecular epidemiology of carbapenem non-susceptible Klebsiella pneumoniae, Escherichia coli, Acinetobacter baumannii, Pseudomonas aeruginosa from medical centres Mexico using whole genome sequencing data analysed with the EPISEQⓇ CS application other bioinformatic platforms. Clinical isolates collected 28 in included carbapenem-non-susceptible K. pneumoniae (n = 22), E. coli 24), A. baumannii 16), P. 13). Isolates were subjected to Illumina (MiSeq)...
Stenotrophomonas maltophilia is a nonfermenting Gram-negative drug-resistant pathogen that causes healthcare-associated infections. Clinical isolates from Mexico were assessed for biofilm formation using crystal violet staining. Antimicrobial susceptibility was evaluated in planktonic and cells the broth microdilution method. The effects of antibiotics on biofilms visualized fluorescence microscopy. Fifty included this study, which 14 (28%) producers (9 [64%] blood 5 [36%] respiratory...
Clinical data from hospital admissions are typically utilized to determine the prognostic capacity of Coronavirus disease 2019 (COVID-19) indices. However, as status and severity markers evolve over time, time-dependent receiver operating characteristic (ROC) curve analysis becomes more appropriate. The present assessed predictive power for death at various time points throughout patient hospitalization. In a cohort study involving 515 hospitalized patients (General Hospital Number 1 Mexican...
Antimicrobial resistance is a global concern. Analysis of sterile fluids essential because microorganisms are defined as significant in most cases. Blood, cerebrospinal, and pleural frequently received the microbiology lab they associated with considerable rates morbi-mortality. Knowledge epidemiology these samples needed to choose proper empirical treatments due importance reducing selection pressure.We used retrospective laboratory data blood, CSF, fluid collected from patients Mexico...
SUMMARY A total of 22 nonsplenectomized Hereford, Holstein-Friesian, and cross-bred 18-month-old cattle were used to assess the degree protection conferred by previous infection with Babesia bovis or B bigemina against disease from tick-borne challenge exposure heterologous species. Prior did not significantly ( P < 0.05) reduce susceptibility caused Carrier infections activated during species exposure, nor was severity challenge-exposure aggravated. Immunologic cross-reactivity in...
Patients on dialysis have important changes in body composition.To determine the correlation between skinfold thickness (SKF) and bioimpedance analysis (BIA) for estimating fat mass (FM) lean (LBM) patients undergoing hemodialysis (HD) peritoneal (PD).Cross-sectional study. We included 50 under treatment. To measure SKF, we used Lange® caliper (Beta Technology, California, USA) carried out impedance with Bodystat Quadscan 4000® (Quadscan, Isle of Man, UK). The measurements were performed...
Abstract Objective To analyze the resistance to antimicrobials in clinical isolates from pediatric patients Mexico. Methods Susceptibility data relevant specimens were collected population over 6 months 25 centers 17 states of Mexico and analyzed using WHONET 5.6 software. Data stratified into three age groups: younger than 2 years, 18 years. Results For Escherichia coli, infant/toddler group had higher rates ampicillin, ampicillin-sulbactam, cefuroxime, cefepime, gentamicin, quinolones (p...