A5028060691- Viral gastroenteritis research and epidemiology
- Long-Term Effects of COVID-19
- Virus-based gene therapy research
- SARS-CoV-2 detection and testing
- Viral Infectious Diseases and Gene Expression in Insects
- COVID-19 Pandemic Impacts
- Chronic Disease Management Strategies
- SARS-CoV-2 and COVID-19 Research
- Antibiotics Pharmacokinetics and Efficacy
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Rheumatoid Arthritis Research and Therapies
- Orthopedic Infections and Treatments
- Cocoa and Sweet Potato Agronomy
- Brain Metastases and Treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Mobile Health and mHealth Applications
- Phytochemical compounds biological activities
- Context-Aware Activity Recognition Systems
- Management of metastatic bone disease
- Artificial Intelligence in Healthcare
- Total Knee Arthroplasty Outcomes
- Intensive Care Unit Cognitive Disorders
- Traditional and Medicinal Uses of Annonaceae
- Acute Kidney Injury Research
- Knee injuries and reconstruction techniques
Universidad de Colima
2019-2024
Coronavirus disease 2019 (COVID‑19) is currently the major public health problem worldwide. Neutral electrolyzed saline solution that contains reactive chlorine and oxygen species may be an effective therapeutic. In present study, treatment efficacy of intravenous and/or nebulized neutral combined with usual medical care vs. alone was evaluated in ambulatory patients COVID‑19. A prospective, 2‑arm, parallel‑group, randomized, open‑label, multi‑center, phase I‑II clinical trial including 214...
Introduction: COVID-19 pandemic affects human health and the global economy. Its evolution is unpredictable, making it hard for governments to provide response actions suited all populations. Meanwhile, informal street workers carry on with their labor despite contingency measures sustain lives. The objective was conduct a case-control study become aware of how vendors' economy affected during pandemic.
 Methodology: During phase 2 in Mexican suburban city. We interviewed vendors...
The severity of adenovirus infection or the success adenovirus-vectorized gene therapy largely depends on efficiency viral entry into cells. Various drugs can alter entry. This study evaluated effects dexamethasone, paracetamol, diclofenac, ibuprofen, and ketorolac cells in vitro vivo. SiHa cell cultures pretreated with ketorolac, no drug were exposed to Ad-BGal vector. percentage showing vector was quantified microscopically. In vivo, BALB-C mice for 7 days intravenously (IV) via oral (VO)....
Background and Objectives: Gentamicin (GM) is a nephrotoxic aminoglycoside. Neutral electrolyzed saline (SES) compound with anti-inflammatory, antioxidant, immunomodulatory properties. The objective of the present study was to evaluate whether kidney damage by GM can be prevented and/or reversed through administration SES. Materials Methods: carried out as prospective, single-blind, five-arm, parallel-group, randomized, preclinical trial. nephrotoxicity model established in male BALB/c mice...
Introduction: Due to the coronavirus pandemic, identifying infected individuals has become key limiting its spread. Virus nucleic acid real-time RT-PCR testing current standard diagnostic method but high demand could lead shortages. Therefore, we propose a detection strategy using one-step nested RT-PCR.
 Methodology: The nucleotide region in ORF1ab gene that greatest differences between human and bat was selected. Primers were designed after sequence. All primers are species-specific...
Background: Coronavirus disease (COVID-19) is currently the main public health problem worldwide. The administration of neutral electrolyzed saline, a solution that contains reactive species chlorine and oxygen (ROS), may be an effective therapeutic alternative due to its immunomodulating characteristics, in systemic inflammation control, as well immune response improvement, promoting control viral infection. present study evaluated efficacy treatment with intravenous and/or nebulized saline...
Prostate cancer (PCa) is the second most common non-dermatological in men and a growing public health problem. Castration-resistant disease (CRD) advanced stage of difficult to control. Patients with CRD may no longer accept conventional therapies as they are not appropriate clinical conditions or refuse receive it. Given that inflammation an essential component origin progression, anti-inflammatory agents could be therapeutic option fenamates one proposed choices. A prospective, randomized,...
Rheumatoid arthritis is globally present in about 1% of the population. This autoinflammatory disease modifies connective tissue, causing pain and inflammation joints. Over time, it causes loss joint cartilage bone mass, decreasing patient's quality life. Treatment options now available either give symptomatic alleviation or alter process. Nonetheless, adherence to chronic treatment typically limited due adverse effects. As a result, new therapy approaches, such as systemic administration...
During phase 2 of the COVID-19 pandemic in a Mexican City, informal street vendors (cases) and formal employees (controls) were interviewed. A total 82.6% preferred to expose themselves coronavirus than stop working, compared with 18.4% (adjusted OR = 19.4, 95%CI: 4.6-81.7, p < 0.001). Street had 7 times less fear dying from 0.14, 95% CI: 0.03-0.5, 0.005) showed 16-times greater lack real concern for increase cases their community 0.06, 0.01-0.3, 0.002). group poorest adherence household...
The bioactive cell-free formulation (BIOF2) for cartilage regeneration has shown a major therapeutic response in severe knee osteoarthritis. However, its effect on patients with mild or moderate stages of the disease not been studied.To evaluate Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, minimal clinically important improvement (MCII) sleep disturbances mild, moderate, osteoarthritis (OA) novel treatment (BIOF2).An open-label, nonrandomized,...
Diabetes mellitus is a disease with no cure that can cause complications and even death. Moreover, over time, it will lead to chronic complications. Predictive models have been used identify people tendency develop diabetes mellitus. At the same there limited information regarding of patients diabetes. Our study aimed at creating machine-learning model be able risk factors diabetic patient developing such as amputations, myocardial infarction, stroke, nephropathy, retinopathy. The design...
Introduction. The present study evaluated the quality of medical care for patients diagnosed with diabetes mellitus (DM), hypertension (HBP), and both pathologies (DM+HBP) within a public health system in Mexico. Methods. 45,498 were included from 2012 to 2015. All information was taken electronic record database. Each patient compared against standard test care. Results. Glycemia goals reached 29.6% DM+HBP, 48.6% DM, 53.2% HBP. serum lipids by 3% 5% 0.2% Glycemia, hypertension, LDL...
Continuous health monitoring in real-time has become essential to improve people's quality of life through medical prescription or personal control. Our goal is develop a wearable IoMT device with heart rate and breathing patterns while an athlete performs physical exercise at high-intensity intervals. The incorporates vital signs sensors record display information mobile application, allowing users track their receive alert if the data exceeds normal parameters.
<sec> <title>BACKGROUND</title> Diabetes Mellitus is a worldwide health problem and the leading cause of premature death with increasing prevalence over time. Usually, along it, Hypertension presents acts as another risk factor that increases mortality risk. Both diseases impact country's while also producing an economic burden for society, causing billions dollars to be invested in their management. </sec> <title>OBJECTIVE</title> The present study evaluated quality medical care patients...