Mario Ramírez-Flores

ORCID: 0000-0003-3375-715X
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About
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Research Areas
  • Cervical Cancer and HPV Research
  • Neuroscience of respiration and sleep
  • Adipose Tissue and Metabolism
  • Regulation of Appetite and Obesity
  • Lipoproteins and Cardiovascular Health
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Viral gastroenteritis research and epidemiology
  • SARS-CoV-2 detection and testing
  • Health and Medical Education
  • Virus-based gene therapy research
  • Diabetes and associated disorders
  • SARS-CoV-2 and COVID-19 Research
  • Long-Term Effects of COVID-19
  • Chronic Disease Management Strategies
  • Genital Health and Disease
  • Biochemical Analysis and Sensing Techniques
  • Family Support in Illness
  • Problem and Project Based Learning
  • Cancer survivorship and care
  • RNA modifications and cancer
  • Lipid metabolism and disorders
  • Inflammatory mediators and NSAID effects
  • Dental Research and COVID-19
  • Olfactory and Sensory Function Studies
  • Digital Mental Health Interventions

Universidad de Colima
2016-2025

Universidad de Guadalajara
2011

Cervical human papillomavirus (HPV+) infection is associated with an increased risk of cervical dysplasia. Although the frequency HPV+ in systemic lupus erythematosus (SLE) has been investigated some races its prevalence Hispanic women still unknown. This cross-sectional study evaluated Mexican SLE ( n = 34) or rheumatoid arthritis (RA) 43) and healthy controls 146). These were interviewed about factors for sexually transmitted infections cytology analysis was performed. viral types...

10.1177/0961203311425517 article EN Lupus 2011-10-21

Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide, with growing concerns about impact omega-6 polyunsaturated fatty acids (n-6 PUFAs) on cardiovascular health. This study aims to evaluate relationship between serum linoleic acid (LA) levels and waist-to-height ratio (WHtR), a recognized risk marker, in children. The research was conducted two parts. First, global analysis publicly available data (2019–2021) explored association nutritional factors CVD prevalence...

10.3390/jcdd12040115 article EN cc-by Journal of Cardiovascular Development and Disease 2025-03-25

Coronavirus disease 2019 (COVID‑19) is currently the major public health problem worldwide. Neutral electrolyzed saline solution that contains reactive chlorine and oxygen species may be an effective therapeutic. In present study, treatment efficacy of intravenous and/or nebulized neutral combined with usual medical care vs. alone was evaluated in ambulatory patients COVID‑19. A prospective, 2‑arm, parallel‑group, randomized, open‑label, multi‑center, phase I‑II clinical trial including 214...

10.3892/etm.2021.10347 article EN Experimental and Therapeutic Medicine 2021-06-29

Introduction: Due to the coronavirus pandemic, identifying infected individuals has become key limiting its spread. Virus nucleic acid real-time RT-PCR testing current standard diagnostic method but high demand could lead shortages. Therefore, we propose a detection strategy using one-step nested RT-PCR.
 Methodology: The nucleotide region in ORF1ab gene that greatest differences between human and bat was selected. Primers were designed after sequence. All primers are species-specific...

10.3855/jidc.12726 article EN cc-by The Journal of Infection in Developing Countries 2020-07-31

Background: Coronavirus disease (COVID-19) is currently the main public health problem worldwide. The administration of neutral electrolyzed saline, a solution that contains reactive species chlorine and oxygen (ROS), may be an effective therapeutic alternative due to its immunomodulating characteristics, in systemic inflammation control, as well immune response improvement, promoting control viral infection. present study evaluated efficacy treatment with intravenous and/or nebulized saline...

10.21203/rs.3.rs-68403/v1 preprint EN cc-by Research Square (Research Square) 2020-09-10

Background: The COVID-19 pandemic significantly impacted mental health and substance use patterns, particularly among young adults. Objective: This study aimed to assess changes in anxiety, depression, self-esteem, university students Mexico before, during, after the pandemic. Methods: Using a repeated cross-sectional design, this was conducted with across three periods: pre-pandemic (2017 2019); during (2021); post-pandemic (2023). A total of 2167 were interviewed one periods. Standardized...

10.3390/diseases12120303 article EN cc-by Diseases 2024-11-27

Human adenovirus 36 (HAdV-36) has been associated with obesity and changes in glucose lipid metabolism. The virus reported to increase insulin sensitivity paradoxically promote weight gain. Because of its effects on metabolism, infection the could alter response several drugs used treat type 2 diabetes (DM2), such as metformin. aim this study was test whether HAdV-36 affects metformin a group obese patients DM2. Methods: In prospective cohort study, 103 newly diagnosed DM2 were divided into...

10.3390/v15071514 article EN cc-by Viruses 2023-07-07

Carnitine palmitoyltransferase IB (CPT1B) and adrenoceptor beta-3 (ADRB3) are critical regulators of fat metabolism. CPT1B transports free acyl groups into mitochondria for oxidation, ADRB3 triggers lipolysis in adipocytes, their respective polymorphisms E531K W64R have been identified as indicators obesity population studies. It is therefore important to understand the effects these mutations on function adipose skeletal muscle tissue, respectively. This study aimed analyze rate plasma...

10.1371/journal.pone.0096791 article EN cc-by PLoS ONE 2014-06-06

Colorectal cancer (CRC) is the third most common and one of main causes death around world. Multiple lines evidence have suggested role corticotropin-releasing hormone (CRH) family in CRC induction, including low expression receptor 2 (CRHR2), which an angiogenesis inhibitor inflammatory modulator. Previous research suggests that CRHR2 colonic intestinal cells can regulate migration, proliferation apoptosis through modulation several pathways. The aim this study was to analyze association...

10.1136/jim-2021-002047 article EN Journal of Investigative Medicine 2021-12-31

Breast cancer survivorship is a recognized risk factor for sexual dysfunction, with various clinical, sociocultural, and psychological factors potentially interacting differently across populations. This study compared anxiety, depression between females breast those without, aiming to identify associated factors. A total of 362 participated, including 227 dysfunction 135 controls. Among them, 195 are survivors, while 167 have no personal history cancer. Key variables were analyzed using...

10.3390/curroncol31110543 article EN cc-by Current Oncology 2024-11-20

Background/Objectives: Averrhoa carambola, or star fruit, is a shrub known for its medicinal properties, especially due to bioactive metabolites identified in roots and fruit with anti-cancer activity. However, the biological effects of leaves remain unexplored. This study aimed assess ethanolic extract from A. carambola on triple-negative breast cancer (TNBC), an aggressive subtype lacking specific therapy. Methods: Phytochemical analysis HPLC profile additional cell line evaluation...

10.3390/pharmaceutics17010002 article EN cc-by Pharmaceutics 2024-12-24

Introduction. The present study evaluated the quality of medical care for patients diagnosed with diabetes mellitus (DM), hypertension (HBP), and both pathologies (DM+HBP) within a public health system in Mexico. Methods. 45,498 were included from 2012 to 2015. All information was taken electronic record database. Each patient compared against standard test care. Results. Glycemia goals reached 29.6% DM+HBP, 48.6% DM, 53.2% HBP. serum lipids by 3% 5% 0.2% Glycemia, hypertension, LDL...

10.1155/2021/7365075 article EN cc-by Journal of Diabetes Research 2021-08-14

Background and Objectives: The commissural nucleus of the tractus solitarius (cNTS) not only responds to glucose levels directly, but also receives afferent signals from liver, carotid chemoreceptors (CChR). In addition, leptin, through its receptors in cNTS, regulates food intake, body weight, blood levels, brain retention (BGR). These leptin effects on cNTS are thought be mediated sympathetic-adrenal system. How these different sources information converging NTS regulate remains largely...

10.3390/medicina58040550 article EN cc-by Medicina 2022-04-16

<sec> <title>BACKGROUND</title> Diabetes Mellitus is a worldwide health problem and the leading cause of premature death with increasing prevalence over time. Usually, along it, Hypertension presents acts as another risk factor that increases mortality risk. Both diseases impact country's while also producing an economic burden for society, causing billions dollars to be invested in their management. </sec> <title>OBJECTIVE</title> The present study evaluated quality medical care patients...

10.2196/preprints.24720 preprint EN 2020-10-01
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