A5029099515- Forensic and Genetic Research
- Genetic diversity and population structure
- Molecular Biology Techniques and Applications
- Forensic Anthropology and Bioarchaeology Studies
- Yersinia bacterium, plague, ectoparasites research
- Drug Transport and Resistance Mechanisms
- Environmental DNA in Biodiversity Studies
- Pharmacogenetics and Drug Metabolism
- Race, Genetics, and Society
- melanin and skin pigmentation
- Genetic and phenotypic traits in livestock
- Diabetes Treatment and Management
- Hemoglobinopathies and Related Disorders
- Reproductive Physiology in Livestock
- Genomics and Chromatin Dynamics
- Reproductive System and Pregnancy
- Cannabis and Cannabinoid Research
- Archaeology and ancient environmental studies
- Endometriosis Research and Treatment
- Wnt/β-catenin signaling in development and cancer
- Colorectal Cancer Treatments and Studies
- Cancer-related molecular mechanisms research
- Adipose Tissue and Metabolism
- Diabetes and associated disorders
- Microbial infections and disease research
Universidad de Guadalajara
2016-2025
Universidad de la Ciénega
2015-2023
Instituto Nacional de Enfermedades Respiratorias
2021
Background: Analyzing Y-chromosome short tandem repeats (Y-STRs) is essential in forensic genetics and population studies. The Yfiler™ Plus kit, which includes 27 Y-STR markers, enhances the discrimination power for kinship applications. However, this genetic system has not been analyzed Mexican populations, limits its application representativeness international databases. Objectives: We wished to examine diversity parameters of Y-STRs included YFiler™ kit two populations from Western...
ABSTRACT Objective To analyze the origin, structure, relationships, and recent admixture in Mexican Native groups based on 15 STRs commonly used human identification. Methods We analyzed 39 population samples using STR databases AmpF l STR® Identifiler kit ( n = 3,135), including Mexican‐Mestizos (admixed), European African populations, as reference. Results Based upon effective size (Ne) differences, were clustered into three regions: i) Center‐Southeast , characterized by larger Ne,...
Rheumatoid Arthritis (RA) is a multifactorial autoimmune disease. Currently, several genes play an important role in the development of The objective was to evaluate association STAT4 rs7574865 and rs897200 gene variants with RA susceptibility, DAS28, RF, anti-CCP Western Southern Mexico populations. Genotyping performed on 476 samples (cases = 240; controls 236) using Taqman® system qPCR probes. Disease activity assessed DAS28 HAQ DI. CRP, ESR, were determined for clinical assessment. Our...
Background: New commercial STR kits have emerged with greater numbers of markers, which allows for obtaining stronger conclusions in forensic casework, has been poorly studied Mexico.Aim: To obtain parameters and to analyse the genetic relationships, structure admixture seven geographic regions Guerrero state (South, Mexico) based on Globalfiler® kit.Subjects methods: A total 245 unrelated Mexican individuals from were analysed kit. Forensic parameters, pairwise comparisons, distances,...
Forensic genomic systems allow simultaneously analyzing identity informative (iiSNPs), ancestry (aiSNPs), and phenotype (piSNPs) genetic markers. Among these kits, the ForenSeq DNA Signature prep (Verogen) analyzes STRs SNPs as well 24 piSNPs from HIrisPlex system to predict hair eye color. We report herein in 88 samples Monterrey City (Northeast, Mexico) based on prep. Phenotypes were predicted by genotype results with both Universal Analysis Software (UAS) web tool of Erasmus Medical...
Human adenovirus 36 (HAdV-36) has been associated with obesity and changes in glucose lipid metabolism. The virus reported to increase insulin sensitivity paradoxically promote weight gain. Because of its effects on metabolism, infection the could alter response several drugs used treat type 2 diabetes (DM2), such as metformin. aim this study was test whether HAdV-36 affects metformin a group obese patients DM2. Methods: In prospective cohort study, 103 newly diagnosed DM2 were divided into...
Early-onset diffuse gastric cancer (EODGC) occurs at or before 50 years of age. Pathogenic mutations and germline deletions in the CDH1 gene (E-cadherin) are well-documented genetic factors associated with causes EODGC.
Abstract Objective To analyze the genetic origin, relationships, structure, and admixture in Mayan Native American groups from Guatemala Mexico based on 15 autosomal short tandem repeats (STRs) loci commonly used human identification (HID). Methods We genotyped 513 unrelated samples STR (AmpFlSTR® Identifiler kit). Moreover, we included 4408 genotypes previously reported, as following: Mayas ( n = 1666) Latin American, European, African 2742) populations. Forensic parameters, distances,...
Abstract Background Short tandem repeats (STRs) are the most widely used genetic markers in forensic genetics. Therefore, it is essential to document population data of new kits designed for human identification purposes, order enable laboratories use these systems interpret and solve caseworks. However, Mexico, there not studies with PowerPlex Fusion 6C System, which included 26 STRs (23 autosomal 3 Y-STRs). Methods Results A total 600 DNA samples from Mexico City were subjected genotyping...
El vitiligo no segmental es una enfermedad contagiosa de la piel, caracterizada por pérdida pigmentación en el cuerpo. cambio apariencia los pacientes ocasiona estigmatización social y afecta negativamente su salud emocional. Este artículo aborda rol del gen HLA-G segmental, destacando un estudio reciente occidente México. Se analizó asociación variante genética (rs66554220) importante para regulación proteína HLA-G. Estos estudios son cruciales definir nuevas estrategias que controlen...