A5015404689- Neuroscience of respiration and sleep
- Adipose Tissue and Metabolism
- Nitric Oxide and Endothelin Effects
- Regulation of Appetite and Obesity
- Sleep and Wakefulness Research
- Heart Rate Variability and Autonomic Control
- Neuroendocrine regulation and behavior
- Biochemical Analysis and Sensing Techniques
- Pancreatic function and diabetes
- Nerve injury and regeneration
- Circadian rhythm and melatonin
- High Altitude and Hypoxia
- Diabetes and associated disorders
- Psychedelics and Drug Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Cannabis and Cannabinoid Research
- Neurogenesis and neuroplasticity mechanisms
- Eicosanoids and Hypertension Pharmacology
- Advanced Glycation End Products research
- Neonatal and fetal brain pathology
- Biochemical effects in animals
- Receptor Mechanisms and Signaling
- Diabetes Management and Research
- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
Universidad de Colima
2014-2025
Center for Research and Advanced Studies of the National Polytechnic Institute
2003
Background: In recent years, the role of neurotrophins and their receptors in peripheral tissues has been great interest. At a metabolic level, brain-derived neurotrophic factor (BDNF) its receptor trkB have reported to participate insulin secretion from pancreas response increases circulating blood glucose. Objetive: To determines BDNF-trkB pathway pancreatic morphology rats fed cafeteria-style diet for 16 weeks. Methods: For study, male Wistar strain were divided into three groups as...
Background Physical exercise improves glucose metabolism and insulin sensitivity. Brain-derived neurotrophic factor (BDNF) enhances activity in diabetic rodents. Because physical modifies BDNF production, this study aimed to investigate the effects of chronic on plasma levels possible tolerance modification healthy rats. Methods Wistar rats were divided into five groups: control (sedentary, C); moderate- intensity training (MIT); MIT plus K252A TrkB blocker (MITK); high-intensity (HIT); HIT...
Brain-derived neurotrophic factor (BDNF) protein expression is sensitive to cellular activity. In the sedentary state, BDNF affected by muscle phenotype.Eighteen Wistar rats were divided into following 3 groups: (S); moderate-intensity training (MIT); and high-intensity (HIT). The protocol lasted 8 weeks. Forty-eight hours after training, total RNA levels in soleus plantaris muscles obtained.In plantaris, level was lower HIT than S group (P < 0.05). A similar effect found (without...
The function and morphology of β-cells is largely dependent on insulin demand. As cover a bigger cell proportion in pancreas islets, changes producer cells affect the whole pancreatic islet morphology. Growth factors as neurotrophins regulate physiology, besides; physical exercise increases sensitivity, further modifies brain derived neurotrophic factor (BDNF) concentration plasma. aim this study was to investigate effects chronic (running treadmill for 8 weeks) intensity morphometry healthy...
Hypoxic stimulation of the carotid body receptors (CBR) results in a rapid hyperglycemia with an increase brain glucose retention. Previous work indicates that neurohypophysectomy inhibits this hyperglycemic response. Here, we show systemic arginine vasopressin (AVP) induced transient, but significant, blood levels and increased retention, response similar to observed after CBR stimulation. Comparable were obtained intracerebral infusion AVP. Systemic AVP-induced changes maintained...
The carotid body (CB) senses changes in arterial O
Background and objectives: Adipose tissue skeletal muscle secrete adiponectin, a hormone abundantly secreted by adipocytes, that through the adiponectin receptor, regulate glucose lipid metabolism. Adiponectin appears to protect muscles from inflammatory damage induced oxidative stress. It has been suggested decreased levels could be associated with pathologic conditions, including obesity diabetes. Furthermore, some studies suggest exercise have beneficial effect increasing levels, but this...
Inducing carotid body anoxia through the administration of cyanide can result in oxygen deprivation. The lack activates cellular responses specific regions central nervous system, including Nucleus Tractus Solitarius, hypothalamus, hippocampus, and amygdala, which are regulated by afferent pathways from chemosensitive receptors. These receptors modulated brain-derived neurotrophic factor receptor TrkB. Oxygen deprivation cause neuroinflammation brain that activated body. To investigate how...