A5080358968- Natural Antidiabetic Agents Studies
- Mitochondrial Function and Pathology
- Phytochemicals and Antioxidant Activities
- Adipose Tissue and Metabolism
- Advanced Glycation End Products research
- Cardiac Ischemia and Reperfusion
- Antioxidant Activity and Oxidative Stress
- Fungal and yeast genetics research
- Fermentation and Sensory Analysis
- Pharmacology and Obesity Treatment
- Nitric Oxide and Endothelin Effects
- Liver Disease Diagnosis and Treatment
- Essential Oils and Antimicrobial Activity
- Metabolism and Genetic Disorders
- Biochemical effects in animals
- Metabolomics and Mass Spectrometry Studies
- Psidium guajava Extracts and Applications
- Horticultural and Viticultural Research
- Diet and metabolism studies
- Exercise and Physiological Responses
- Peroxisome Proliferator-Activated Receptors
- Amino Acid Enzymes and Metabolism
- Phytochemistry and Biological Activities
- Drug-Induced Hepatotoxicity and Protection
- Eicosanoids and Hypertension Pharmacology
Universidad Michoacana de San Nicolás de Hidalgo
2016-2025
The University of Texas Medical Branch at Galveston
2007-2017
National Research Institute of Brewing
2017
Universidad Nacional Autónoma de México
1983-1991
Hahnemann University Hospital
1990
Abstract The prevalence of allergies and asthma among the world’s population has been steadily increasing due to environmental factors. It described that exposure ozone, diesel exhaust particles, or tobacco smoke exacerbates allergic inflammation in lungs. These oxidants increase levels cellular reactive oxygen species (ROS) induce mitochondrial dysfunction airway epithelium. In this study, we investigated involvement preexisting exacerbation inflammation. After oxidative insult induced by...
Diabetic encephalopathy is a diabetic complication related to the metabolic alterations featuring diabetes. Diabetes characterized by increased lipid peroxidation, altered glutathione redox status, exacerbated levels of ROS, and mitochondrial dysfunction. Although pathophysiology remains be clarified, oxidative stress dysfunction play crucial role in pathogenesis chronic complications. Taking this into consideration, aim work was evaluate effects 90-day avocado oil intake brain function...
Nitrosative and oxidative stress play a key role in obesity diabetes-related mitochondrial dysfunction. The objective was to investigate the effect of curcumin treatment on state 3 4 oxygen consumption, nitric oxide (NO) synthesis, ATPase activity lipid oxidation mitochondria isolated from liver kidneys diabetic db/db mice. Hyperglycaemia increased consumption decreased NO synthesis mice relative control In kidney mitochondria, hyperglycaemia thiobarbituric acid-reactive substances (TBARS)...
Guava leaf (Psidium guajava L.) extracts are used in both traditional medicine and the pharmaceutical industry. The antioxidant compounds P. leaves can have positive effects including anti-inflammatory, anti-hyperglycemic, hepatoprotective, analgesic, anti-cancer effects, as well protecting against cardiovascular diseases. In present study, phenolic vitro capacity were measured obtained with polar non-polar solvents from of two varieties guava, Calvillo Siglo XXI Hidrozac. quantity total...
Stress tolerance is a key attribute that must be considered when using yeast cells for industrial applications. High temperature one factor can cause stress in yeast. environmental particular may exert natural selection pressure to evolve yeasts into thermotolerant strains. In the present study, three (Saccharomyces cerevisiae, MC4, and Kluyveromyces marxianus, OFF1 SLP1) isolated from hot environments were exposed increased temperatures then compared with laboratory strain. Their resistance...
The aim of this study was to investigate the
High fat or fructose induces non-alcoholic fatty liver disease (NAFLD) accompanied of mitochondrial dysfunction and oxidative stress. Controversy remains about whether is more deleterious for NAFLD development. To get insights this issue to determine if the severity induced by related degree dysfunction, we compared effects diets containing high (HF), (Fr) plus (HF + Fr) on development, function, ROS production lipid peroxidation.Wistar rats were assigned four groups: Control, fed with...
Lactoferrin is a non-heme iron-binding glycoprotein, produced by mucosal epithelial cells and granulocytes in most mammalian species. It involved regulation of immune responses, possesses anti-oxidant, anti-carcinogenic, anti-inflammatory properties, provides protection against various microbial infections. In addition, lactoferrin has been implicated the development insult-induced systemic inflammatory response syndrome (SIRS) its progression into septic conditions vivo. Here we show...
Biogenesis and recycling of iron-sulfur (Fe-S) clusters play important roles in the iron homeostasis mechanisms involved mitochondrial function. In Saccharomyces cerevisiae, Fe-S are assembled into apoproteins by cluster machinery (ISC). The aim present study was to determine effects ISC gene deletion consequent release under oxidative stress conditions on functionality S. cerevisiae. Reactive oxygen species (ROS) generation, caused H2O2, menadione, or ethanol, associated with a loss...
Gestational diabetes (GD) has been linked with an increased risk of developing metabolic disorders and behavioral abnormalities in the offspring. Oxidative stress is strongly associated neurodegeneration cognitive disruption. In offspring brains a GD experimental rat model, oxidative prenatal postnatal stages was reported. However, long-term alterations to behavior stress, caused by changes cerebral cortex hippocampus, remain unclear. this study, we evaluated effect on young adult male...
In the present study, we investigated composition and antioxidant activity of hexanic extract Eryngium carlinae inflorescences by employing in vitro assays to measure capacity 2,2-diphenyl-1-picrylhydrazyl scavenging activity. We also applied Saccharomyces cerevisiae, under hydrogen peroxide-induced stress. Finally, tested male Wistar rats with without streptozotocin-induced diabetes. The compounds were analyzed gas-chromatography-mass spectrometry, which revealed mainly terpenes...
Non-alcoholic fatty liver disease (NAFLD) is characterized by lipid accumulation in hepatocytes, and advanced stages, inflammation fibrosis. Excessive ROS production due to mitochondrial dysfunction contributes NAFLD development, making the decrease an emerging target alleviate NAFLD. Previously, we have shown that avocado oil, a source of several bioactive compounds with antioxidant effects, decreases oxidative stress improving function electron transport chain (ETC) decreasing levels...
Diabetes mellitus (DM) is a significant risk factor for the development of cardiovascular complications. This study was undertaken to investigate effect chronic administration ethanolic extract Eryngium carlinae on glucose, creatinine, uric acid, total cholesterol, and triglycerides levels in serum streptozotocin- (STZ-) induced diabetic rats. Triglycerides, acid increased from The treatment with E. prevented these changes. reduced triglycerides. Thus able reduce hyperlipidemia related...