A5077184853- Reproductive System and Pregnancy
- Carbohydrate Chemistry and Synthesis
- Algal biology and biofuel production
- Lipid metabolism and biosynthesis
- Pregnancy and preeclampsia studies
- Monoclonal and Polyclonal Antibodies Research
- Glycosylation and Glycoproteins Research
- Galectins and Cancer Biology
- Pregnancy and Medication Impact
- Chemical Synthesis and Analysis
- Immune Cell Function and Interaction
- Synthetic Organic Chemistry Methods
- Prenatal Screening and Diagnostics
- Congenital Heart Disease Studies
- Proteoglycans and glycosaminoglycans research
- Reproductive Physiology in Livestock
- Protein purification and stability
- Neonatal and fetal brain pathology
- Animal Genetics and Reproduction
- Synthesis of Organic Compounds
- T-cell and Retrovirus Studies
- Cyclopropane Reaction Mechanisms
- Reproductive Biology and Fertility
- Ectopic Pregnancy Diagnosis and Management
- Ultrasound in Clinical Applications
Universidad de Sonora
2025
University of Buenos Aires
2006-2023
Consejo Nacional de Investigaciones Científicas y Técnicas
2004-2023
Universidade Federal da Bahia
2014-2021
Instituto de Química Orgánica General
2014-2018
University of Bristol
2016
Consejo Superior de Investigaciones Científicas
2014-2015
Institute of Astronomy and Space Physics
1992-2012
Friedrich Schiller University Jena
2002
Instituto de Estudios Universitarios
1992
The use of a bifunctional cinchona/thiourea organocatalyst for the direct and α-stereoselective glycosylation 2-nitrogalactals is demonstrated first time. conditions are mild, practical, applicable to wide range glycoside acceptors with products being isolated in good excellent yields. method exemplified synthesis mucin type Core 6 7 glycopeptides.
Background: In recent years, the role of neurotrophins and their receptors in peripheral tissues has been great interest. At a metabolic level, brain-derived neurotrophic factor (BDNF) its receptor trkB have reported to participate insulin secretion from pancreas response increases circulating blood glucose. Objetive: To determines BDNF-trkB pathway pancreatic morphology rats fed cafeteria-style diet for 16 weeks. Methods: For study, male Wistar strain were divided into three groups as...
Microalgal triglyceride (TAG) synthesis has attracted considerable attention. Particular emphasis been put towards characterizing the algal homologs of canonical rate-limiting enzymes, diacylglycerol acyltransferase (DGAT) and phospholipid:diacylglycerol (PDAT). Less work done to analyze from a phylogenetic perspective. In this work, we used HMMER iterative profiling functional analyses determine number sequence characteristics DGAT PDAT, as well related sequences that constitute their...
Canellada A, Färber Zenclussen AC, Gentile T, Dokmetjian J, Keil Blois S, Miranda Berod L, Gutiérrez G, Markert UR, Margni RA. Interleukin regulation of asymmetric antibody synthesized by isolated placental B cells. AJRI 2002; 48: 275–282 © Blackwell Munksgaard, 2002 PROBLEM: Protecting antibodies against trophoblast surface molecules were previously described. Here we analysed the synthesis IgG B‐lymphocytes. METHOD OF STUDY: cells from human term placenta and cord blood, stimulated with...
Problem Multiparity status has been found to bring beneficial effects both the maintenance of pregnancy and offspring; however, these have not fully explained. We previously reported that placentae obtained from multiparous females belonging a syngeneic mouse crossbreeding showed an important increase in number placental macrophages, suggesting they might constitute protective subpopulation. Taking into account macrophage‐colony stimulating factor (M‐CSF) granulocyte‐colony (G‐CSF) proved...
Abstract The fetal–placental unit is a semi‐allograft and immunological recognition of pregnancy, together with the subsequent response maternal immune system, necessary for successful pregnancy. Dendritic cells (DC) show biological plasticity that confers them special characteristics regulating both immunity tolerance. Therapy employing DC proved to diminish abortion in DBA/2J‐mated CBA/J females; however, underlying mechanisms remain unknown. Here, we evaluated whether therapy influences...
Novel substrates that combine dicobalt hexacarbonyl propargyl (Nicholas) and pyranose-derived allylic (Ferrier) cations have been generated by treatment of hexacarbonyldicobalt (C-1)-alkynyl glycals with BF3 (.) Et2 O. The study these has resulted in the discovery novel reaction pathways shown to be associated nature O-6 substituent starting alkynyl glycals. Accordingly, compounds resulting from ring expansion (oxepanes), contraction (tetrahydrofurans), or branched pyranoses, incorporation...
Beneficial effects of multiparity status have been previously reported by different authors. However, this fact has not fully explained. Taking into consideration the influence parity on in vitro asymmetric/protective antibodies and that interleukin-6 (IL-6) is involved production immune-regulatory functions placental macrophages, aim work was to compare IL-6 tissue macrophage presence mice with age status.Three groups (CBA/J x CBA/J) were analyzed: primiparous young (PY: 3.0 +/- 0.5 months...
Novel pyranose derivatives that display Ferrier‐ and Ferrier‐Nicholas‐like reactivity have been designed. These systems: 1‐ C ‐alkynyl‐2‐deoxy‐2‐ ‐methylene pyranosides (Ferrier), their corresponding dicobalthexacarbonyl alkenyl (Ferrier‐Nicholas), which can be accessed by a concise synthetic route from commercially available tri‐ O ‐acetyl‐ d ‐glucal, allow the incorporation of two nucleophiles (at positions C‐3 C‐2′) in ring. The study these systems has resulted discovery novel reaction...
PROBLEM: To investigate how the factors secreted by human placenta modify quality and quantity of antibody produced hybridoma as well its cellular proliferation. METHOD: Supernatants cultures (PS) were added to a mouse IgG1 culture producing anti‐DNP antibodies. The monoclonal produced, nature these antibodies proliferation cells studied. RESULT: It was found that PS augmented 40–50% total increased proportion asymmetric (blocking) from 15% 30%, diminished proliferation, measured 3...
PROBLEM: The in vitro immunomodulating effect of placental culture supernatants (PSs) obtained from two H‐2k × H‐2d allogeneic crossbreedings, the CBA/J DBA/2 abortion‐prone mating combination, and reproductively normal pregnancy BALB/c crossbreeding were compared, influence previous deliveries was evaluated. behavior placentae females with pregnancies by males also investigated. METHOD OF STUDY: Supernatants cultures murine added to a mouse immunoglobulin (Ig) G1 hybridoma which produced...